Search Results - "Vihtelic, Thomas S"

Time course analysis of gene expression during light‐induced photoreceptor cell death and regeneration in albino zebrafish by Kassen, Sean C., Ramanan, Vijay, Montgomery, Jacob E., T. Burket, Christopher, Liu, Chang‐Gong, Vihtelic, Thomas S., Hyde, David R.

“…Constant intense light causes apoptosis of rod and cone photoreceptors in adult albino zebrafish. The photoreceptors subsequently regenerate from proliferating…”
Get full text

Cellular expression of Midkine-a and Midkine-b during retinal development and photoreceptor regeneration in zebrafish by Calinescu, Anda-Alexandra, Vihtelic, Thomas S., Hyde, David R., Hitchcock, Peter F.

“…In the retina of adult teleosts, stem cells are sustained in two specialized niches: the ciliary marginal zone (CMZ) and the microenvironment surrounding adult…”
Get full text

Genetic determinants of hyaloid and retinal vasculature in zebrafish by Alvarez, Yolanda, Cederlund, Maria L, Cottell, David C, Bill, Brent R, Ekker, Stephen C, Torres-Vazquez, Jesus, Weinstein, Brant M, Hyde, David R, Vihtelic, Thomas S, Kennedy, Breandan N

“…The retinal vasculature is a capillary network of blood vessels that nourishes the inner retina of most mammals. Developmental abnormalities or microvascular…”
Get full text

Retinal regional differences in photoreceptor cell death and regeneration in light-lesioned albino zebrafish by Vihtelic, Thomas S., Soverly, Jonathan E., Kassen, Sean C., Hyde, David R.

“…Teleost fish regenerate retinal cells from a population of inner nuclear layer (INL) stem cells. To characterize photoreceptor regeneration in zebrafish (…”
Get full text

Mutations in laminin alpha 1 result in complex, lens-independent ocular phenotypes in zebrafish by Semina, Elena V., Bosenko, Dmitry V., Zinkevich, Natalya C., Soules, Kelly A., Hyde, David R., Vihtelic, Thomas S., Willer, Gregory B., Gregg, Ronald G., Link, Brian A.

“…We report phenotypic and genetic analyses of a recessive, larval lethal zebrafish mutant, bal a69 , characterized by severe eye defects and shortened body…”
Get full text

Phosphatidylinositol synthase is required for lens structural integrity and photoreceptor cell survival in the zebrafish eye by Murphy, Taylor R., Vihtelic, Thomas S., Ile, Kristina E., Watson, Corey T., Willer, Gregory B., Gregg, Ronald G., Bankaitis, Vytas A., Hyde, David R.

“…The zebrafish lens opaque ( lop) mutant was previously isolated in a genetic screen and shown to lack rod and cone photoreceptors and exhibit lens opacity, or…”
Get full text

The loss of vacuolar protein sorting 11 (vps11) causes retinal pathogenesis in a vertebrate model of syndromic albinism by Thomas, Jennifer L, Vihtelic, Thomas S, denDekker, Aaron D, Willer, Gregory, Luo, Xixia, Murphy, Taylor R, Gregg, Ronald G, Hyde, David R, Thummel, Ryan

“…To establish the zebrafish platinum mutant as a model for studying vision defects caused by syndromic albinism diseases such as Chediak-Higashi syndrome,…”
Get full text

Age-Related Cone Abnormalities in Zebrafish with Genetic Lesions in Sonic Hedgehog by Stenkamp, Deborah L, Satterfield, Rosanna, Muhunthan, Kalyani, Sherpa, Tshering, Vihtelic, Thomas S, Cameron, David A

“…Sonic hedgehog (Shh) signaling is essential for photoreceptor differentiation and retinal cell survival in embryonic zebrafish. The study was conducted to…”
Get full text

Teleost Lens Development and Degeneration by Vihtelic, Thomas S

“…The transparent properties of the lens and its ability to focus light onto the retina are critical for normal vision. Optical clarity of the lens is achieved…”
Get full text

Efficacy of fluralaner spot-on solution against induced infestations with Rhipicephalus sanguineus on dogs by Taenzler, Janina, Liebenberg, Julian, Mienie, Machiel, Everett, William R, Young, David R, Vihtelic, Thomas S, Sun, Fangshi, Zschiesche, Eva, Roepke, Rainer K A, Heckeroth, Anja R

“…The efficacy of fluralaner spot-on solution administered once topically against induced infestations with Rhipicephalus sanguineus was evaluated in dogs over a…”
Get full text

Expressed sequence tag analysis of zebrafish eye tissues for NEIBank by Vihtelic, Thomas S, Fadool, James M, Gao, James, Thornton, Kimberley A, Hyde, David R, Wistow, Graeme

“…To characterize gene expression patterns in various tissues of the zebrafish (Danio rerio) eye and identify zebrafish orthologs of human genes by expressed…”
Get full text

Cellular expression of midkine-a and midkine-b during retinal development and photoreceptor regeneration in zebrafish by Calinescu, Anda-Alexandra, Vihtelic, Thomas S., Hyde, David R., Hitchcock, Peter F.

“…In the retina of adult teleosts, stem cells are sustained in two specialized niches: the ciliary marginal zone (CMZ) and the microenvironment surrounding adult…”
Get full text

Cellular expression of midkine-a and midkine-b during retinal development and photoreceptor regeneration in zebrafish by Calinescu, Anda-Alexandra, Vihtelic, Thomas S., Hyde, David R., Hitchcock, Peter F.

“…In the retina of adult teleosts, stem cells are sustained in two specialized niches: the ciliary marginal zone (CMZ) and the microenvironment surrounding adult…”
Get full text

Gene duplication and separation of functions in αB‐crystallin from zebrafish (Danio rerio) by Smith, Amber A., Wyatt, Keith, Vacha, Jennifer, Vihtelic, Thomas S., Samuel Zigler, J., Wistow, Graeme J., Posner, Mason

“…We previously reported that zebrafish αB‐crystallin is not constitutively expressed in nervous or muscular tissue and has reduced chaperone‐like activity…”
Get full text

Immunohistochemical evidence for multiple photosystems in box jellyfish by Ekström, Peter, Garm, Anders, Pålsson, Jonas, Vihtelic, Thomas S., Nilsson, Dan-Eric

“…Cubomedusae (box jellyfish) possess a remarkable visual system with 24 eyes distributed in four sensory structures termed rhopalia. Each rhopalium is equipped…”
Get full text

Zebrafish mutagenesis yields eye morphological mutants with retinal and lens defects by Vihtelic, Thomas S, Hyde, David R

“…A chemical mutagenesis to identify zebrafish eye morphological mutants was performed by screening F 3 larvae at 5 and 7 days post-fertilization (dpf) for…”
Get full text

Lengsin expression and function during zebrafish lens formation by Harding, Rachel L., Howley, Sinéad, Baker, Lee J., Murphy, Taylor R., Archer, William E., Wistow, Graeme, Hyde, David R., Vihtelic, Thomas S.

“…A zebrafish ortholog of human lengsin was identified by EST analysis of an adult lens cDNA library. During zebrafish development, lengsin transcription is…”
Get full text

Isolation of a Zebrafish Rod Opsin Promoter to Generate a Transgenic Zebrafish Line Expressing Enhanced Green Fluorescent Protein in Rod Photoreceptors by Kennedy, B N, Vihtelic, T S, Checkley, L, Vaughan, K T, Hyde, D R

“…To exploit zebrafish as a transgenic model, tissue-specific promoters must be identified. We isolated a 20-kilobase (kbp) zebrafish rod opsin genomic clone,…”
Get full text

Lens opacity and photoreceptor degeneration in the zebrafish lens opaque mutant by Vihtelic, Thomas S., Yamamoto, Yoshiyuki, Springer, Sandra S., Jeffery, William R., Hyde, David R.

“…The zebrafish lens opaque (lop) mutant was identified in a chemical mutagenesis screen. The lop mutant, which develops normally through 4 days…”
Get full text

Localization of Drosophila retinal degeneration B, a membrane-associated phosphatidylinositol transfer protein by Vihtelic, T.S, Goebl, M, Milligan, S, O'Tousa, J.E, Hyde, D.R

“…The Drosophila retinal degeneration B (rdgB) mutation causes abnormal photoreceptor response and light-enhanced retinal degeneration. Immunoblots using…”
Get full text