Search Results - "Vihko, Pirkko T"

Transmembrane prostatic acid phosphatase (TMPAP) interacts with snapin and deficient mice develop prostate adenocarcinoma by Quintero, Ileana B, Herrala, Annakaisa M, Araujo, César L, Pulkka, Anitta E, Hautaniemi, Sampsa, Ovaska, Kristian, Pryazhnikov, Evgeny, Kulesskiy, Evgeny, Ruuth, Maija K, Soini, Ylermi, Sormunen, Raija T, Khirug, Leonard, Vihko, Pirkko T

“…The molecular mechanisms underlying prostate carcinogenesis are poorly understood. Prostatic acid phosphatase (PAP), a prostatic epithelial secretion marker,…”
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17β-Hydroxysteroid dehydrogenase type 1 is an independent prognostic marker in breast cancer by ODUWOLE, Olayiwola O, LI, Yan, ISOMAA, Veli V, MÄNTYNIEMI, Anne, PULKKA, Anitta E, SOINI, Ylermi, VIHKO, Pirkko T

“…Estrogens have an important role in the development and progression of breast cancer. 17β-Hydroxysteroid dehydrogenase type 1 (17HSD1), type 2 (17HSD2), and…”
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Expression of transmembrane serine protease TMPRSS2 in mouse and human tissues by Vaarala, Markku H., Porvari, Katja S., Kellokumpu, Sakari, Kyllönen, Atte P., Vihko, Pirkko T.

“…The purpose of this study was to clarify the expression of TMPRSS2 in mice during development and to compare the tissue distribution of the transcripts in…”
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Transmembrane prostatic acid phosphatase (TMPAP) delays cells in G1 phase of the cell cycle by Araujo, César L., Quintero, Ileana B., Ovaska, Kristian, Herrala, Annakaisa M., Hautaniemi, Sampsa, Vihko, Pirkko T.

“…BACKGROUND Prostate adenocarcinoma is the most common form of prostate cancer. We have previously shown in a murine model that prostatic acid phosphatase (PAP)…”
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Prostatic acid phosphatase is not a prostate specific target by QUINTERO, Ileana B, ARAUJO, César L, VIHKO, Pirkko T, PULKKA, Anitta E, WIRKKALA, Riikka S, HERRALA, Annakaisa M, ESKELINEN, Eeva-Liisa, JOKITALO, Eija, HELLSTRÖM, Pekka A, TUOMINEN, Hannu J, HIRVIKOSKI, Pasi P

“…Prostatic acid phosphatase (PAP) is currently evaluated as a target for vaccine immunotherapy of prostate cancer. This is based on the previous knowledge about…”
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Structure of Acid phosphatases by Araujo, César L, Vihko, Pirkko T

“…Acid phosphatases are enzymes that have been studied extensively due to the fact that their dysregulation is associated with pathophysiological conditions…”
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Downregulation of estrogen‐metabolizing 17β‐hydroxysteroid dehydrogenase Type 2 expression correlates inversely with Ki67 proliferation marker in colon‐cancer development by Oduwole, Olayiwola O., Isomaa, Veli V., Nokelainen, Pasi A., Stenbäck, Frej, Vihko, Pirkko T.

“…The 17HSDs are a group of isozymes that catalyze the interconversion between high‐activity 17β‐hydroxysteroids and low‐activity 17‐ketosteroids. In the present…”
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Comparison of human prostate specific glandular kallikrein 2 and prostate specific antigen gene expression in prostate with gene amplification and overexpression of prostate specific glandular kallikrein 2 in tumor tissue by Herrala, Annakaisa M., Porvari, Katja S., Kyllönen, Atte P., Vihko, Pirkko T.

“…BACKGROUND There is a need for specific markers that can indicate the different stages of prostate carcinoma. There is ongoing speculation concerning the value…”
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17β-Hydroxysteroid dehydrogenase type 2: independent prognostic significance and evidence of estrogen protection in female patients with colon cancer by Oduwole, Olayiwola O., Mäkinen, Markus J., Isomaa, Veli V., Pulkka, Anitta, Jernvall, Petra, Karttunen, Tuomo J., Vihko, Pirkko T.

“…The mRNA expression of 17β-hydroxysteroid dehydrogenase (17HSD) types 1 and 2 enzymes catalyzing opposite reaction of estrogen metabolism was investigated in…”
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Purification of prostatic acid phosphatase (PAP) for structural and functional studies by Herrala, Annakaisa M, Quintero, Ileana B, Vihko, Pirkko T

“…High-scale purification methods are required for several protein studies such as crystallography, mass spectrometry, circular dichroism, and function. Here we…”
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Several genes encoding ribosomal proteins are over-expressed in prostate-cancer cell lines : Confirmation of L7a and L37 over-expression in prostate-cancer tissue samples by VAARALA, M. H, PORVARI, K. S, KYLLÖNEN, A. P, MUSTONEN, M. V. J, LUKKARINEN, O, VIHKO, P. T

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Transmembrane prostatic acid phosphatase (TMPAP) delays cells in G1 phase of the cell cycle: TMPAP Regulates Cell Growth by Araujo, César L., Quintero, Ileana B., Ovaska, Kristian, Herrala, Annakaisa M., Hautaniemi, Sampsa, Vihko, Pirkko T.

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Prostatic expression of human 5α-reductase type 2 during finasteride therapy : a randomized, double-blind, placebo-controlled study by VAARALA, Markku H, LUKKARINEN, Olavi, MARTTILA, Timo, KYLLÖNEN, Atte P, PORVARI, Katja S, VIHKO, Pirkko T

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Transmembrane Prostatic Acid Phosphatase by Quintero, Ileana B, Herrala, Annakaisa M, Araujo, César L, Pulkka, Anitta E, Hautaniemi, Sampsa, Ovaska, Kristian, Pryazhnikov, Evgeny, Kulesskiy, Evgeny, Ruuth, Maija K, Soini, Ylermi, Sormunen, Raija T, Khirug, Leonard, Vihko, Pirkko T

“…The molecular mechanisms underlying prostate carcinogenesis are poorly understood. Prostatic acid phosphatase (PAP), a prostatic epithelial secretion marker,…”
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Several genes encoding ribosomal proteins are over‐expressed in prostate‐cancer cell lines: Confirmation of L7a and L37 over‐expression in prostate‐cancer tissue samples by Vaarala, Markku H., Porvari, Katja S., Kyllönen, Atte P., Mustonen, Mika V. J., Lukkarinen, Olavi, Vihko, Pirkko T.

“…A cDNA library specific for mRNA over‐expressed in prostate cancer was generated by subtractive hybridization of transcripts originating from prostatic…”
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Cell type‐ and promoter‐dependent modulation of the Wnt signaling pathway by sodium butyrate by Bordonaro, Michael, Lazarova, Darina L., Augenlicht, Leonard H., Sartorelli, Alan C.

“…The Wnt signaling pathway modulates the transcription of genes linked to proliferation, differentiation and tumor progression. β‐Catenin‐Tcf (BCT)‐dependent…”
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Human 17β-hydroxysteroid dehydrogenase type 2 messenger ribonucleic acid expression and localization in term placenta and in endometrium during the menstrual cycle by MUSTONEN, M. V. J, ISOMAA, V. V, VASKIVUO, T, TAPANAINEN, J, POUTANEN, M. H, STENBÄCK, F, VIHKO, R. K, VIHKO, P. T

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17beta-hydroxysteroid dehydrogenase type 1 is an independent prognostic marker in breast cancer by Oduwole, Olayiwola O, Li, Yan, Isomaa, Veli V, Mäntyniemi, Anne, Pulkka, Anitta E, Soini, Ylermi, Vihko, Pirkko T

“…Estrogens have an important role in the development and progression of breast cancer. 17beta-Hydroxysteroid dehydrogenase type 1 (17HSD1), type 2 (17HSD2), and…”
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17Beta-hydroxysteroid dehydrogenase type 2: independent prognostic significance and evidence of estrogen protection in female patients with colon cancer by Oduwole, Olayiwola O, Mäkinen, Markus J, Isomaa, Veli V, Pulkka, Anitta, Jernvall, Petra, Karttunen, Tuomo J, Vihko, Pirkko T

“…The mRNA expression of 17beta-hydroxysteroid dehydrogenase (17HSD) types 1 and 2 enzymes catalyzing opposite reaction of estrogen metabolism was investigated…”
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Cloning of mouse 17 β -hydroxysteroid dehydrogenase type 2, and analysing expression of the mRNAs for types 1, 2, 3, 4 and 5 in mouse embryos and adult tissues by MUSTONEN, Mika V. J., POUTANEN, Matti H., ISOMAA, Veli V., VIHKO, Pirkko T., VIHKO, Reijo K.

“…17β-Hydroxysteroid dehydrogenases (17HSDs) are responsible for the conversion of low-activity sex steroids to more potent forms, and vice versa. 17HSD activity…”
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