Search Results - "Viguier, Mireille"
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Galectin-7 in Epithelial Homeostasis and Carcinomas
Published in International journal of molecular sciences (19-12-2017)“…Galectins are small unglycosylated soluble lectins distributed both inside and outside the cells. They share a conserved domain for the recognition of…”
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2
Identification of a new regulation pathway of EGFR and E-cadherin dynamics
Published in Scientific reports (22-11-2021)“…E-cadherin and EGFR are known to be closely associated hence regulating differentiation and proliferation notably in epithelia. We have previously shown that…”
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3
The Parkinsonism-associated protein DJ-1/Park7 prevents glycation damage in human keratinocyte
Published in Biochemical and biophysical research communications (22-04-2016)“…Reducing sugars and dicarbonyls form covalent adducts with proteins through a nonenzymatic process known as glycation, which inactivates proteins, is increased…”
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Link between the EZH2 noncanonical pathway and microtubule organization center polarization during early T lymphopoiesis
Published in Scientific reports (07-03-2022)“…EZH2 plays an essential role at the β-selection checkpoint of T lymphopoiesis by regulating histone H3 lysine 27 trimethylation (H3K27me3) via its canonical…”
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E-cadherin dynamics is regulated by galectin-7 at epithelial cell surface
Published in Scientific reports (06-12-2017)“…Re-epithelialisation of wounded epidermis is ensured by collective cell migration of keratinocytes. Efficient collective migration requires the maintenance of…”
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Biochemical, Enzymatic, and Computational Characterization of Recurrent Somatic Mutations of the Human Protein Tyrosine Phosphatase PTP1B in Primary Mediastinal B Cell Lymphoma
Published in International journal of molecular sciences (24-06-2022)“…Human protein tyrosine phosphatase 1B (PTP1B) is a ubiquitous non-receptor tyrosine phosphatase that serves as a major negative regulator of tyrosine…”
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Development of a Sensitive Microarray Platform for the Ranking of Galectin Inhibitors: Identification of a Selective Galectin‐3 Inhibitor
Published in Chembiochem : a European journal of chemical biology (14-12-2017)“…Glycan microarrays are useful tools for lectin glycan profiling. The use of a glycan microarray based on evanescent‐field fluorescence detection was herein…”
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Lactosamine‐Based Derivatives as Tools to Delineate the Biological Functions of Galectins: Application to Skin Tissue Repair
Published in Chembiochem : a European journal of chemical biology (18-04-2017)“…Galectins have been recognized as potential novel therapeutic targets for the numerous fundamental biological processes in which they are involved. Galectins…”
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Overexpression of galectin-7 in mouse epidermis leads to loss of cell junctions and defective skin repair
Published in PloS one (05-03-2015)“…The proteins of the galectin family are implicated in many cellular processes, including cell interactions, polarity, intracellular trafficking, and signal…”
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CCR5 deficiency decreases susceptibility to experimental cerebral malaria
Published in Blood (01-06-2003)“…Infection of susceptible mouse strains with Plasmodium berghei ANKA (PbA) is a valuable experimental model of cerebral malaria (CM). Two major pathologic…”
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Oncogenic β-catenin triggers an inflammatory response that determines the aggressiveness of hepatocellular carcinoma in mice
Published in The Journal of clinical investigation (01-02-2012)“…Hepatocellular carcinoma (HCC) is the third leading cause of cancer-related death worldwide. Its pathogenesis is frequently linked to liver inflammation…”
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12
Interplay between EGFR, E-cadherin, and PTP1B in epidermal homeostasis
Published in Tissue barriers (03-07-2023)“…Maintaining epithelial homeostasis is crucial to allow embryo development but also the protective barrier which is ensured by the epidermis. This homeostasis…”
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13
Regression of primary hepatocarcinoma in cancer-prone transgenic mice by local interferon-gamma delivery is associated with macrophages recruitment and nitric oxide production
Published in Cancer gene therapy (01-03-2001)“…The clinical potential of tumor therapies must be evaluated using animal models closely resembling human cancers. We investigated the impact of locally…”
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A tribute to Françoise Poirier (1954-2018)
Published in Glycobiology (Oxford) (01-06-2018)Get full text
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Back Cover: Lactosamine‐Based Derivatives as Tools to Delineate the Biological Functions of Galectins: Application to Skin Tissue Repair (ChemBioChem 8/2017)
Published in Chembiochem : a European journal of chemical biology (18-04-2017)“…The back cover picture shows the collective keratinocyte migration that typically occurs during wound‐healing. This highly efficient and complex process is…”
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On the Pathogenic Role of Brain-Sequestered αβ CD8+ T Cells in Experimental Cerebral Malaria
Published in The Journal of immunology (1950) (01-12-2002)“…Cerebral malaria (CM) develops in a small proportion of persons infected with Plasmodium falciparum and accounts for a substantial proportion of the mortality…”
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Galectins in epithelial functions
Published in Tissue barriers (01-01-2014)“…Galectins are a family of animal lectins comprising 15 members in vertebrates. These proteins are involved in many biological processes including epithelial…”
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Differential presentation of endogenously processed cytotoxic T lymphocyte epitopes by mouse hepatocarcinoma cell lines induced by SV40 large T antigen
Published in International immunology (01-04-1998)“…Tumor cells can have different morphologic or metabolic phenotypes and display genetic instability. Thus they could also vary in their ability to present…”
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Galectins, a class of unconventional lectins
Published in M.S. Médecine sciences (01-05-2015)“…Galectins constitute a family of soluble animal lectins defined by their evolutionary conserved carbohydrate recognition domain and their affinity for…”
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Oncogenic [Beta]-catenin triggers an inflammatory response that determines the aggressiveness of hepatocellular carcinoma in mice
Published in The Journal of clinical investigation (01-02-2012)“…Hepatocellular carcinoma (HCC) is the third leading cause of cancer-related death worldwide. Its pathogenesis is frequently linked to liver inflammation…”
Get full text
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