Search Results - "Vigne, Paul"
-
1
Strong dietary restrictions protect Drosophila against anoxia/reoxygenation injuries
Published in PloS one (01-05-2009)“…Reoxygenation of ischemic tissues is a major factor that determines the severity of cardiovascular diseases. This paper describes the consequences of…”
Get full text
Journal Article -
2
A low protein diet increases the hypoxic tolerance in Drosophila
Published in PloS one (20-12-2006)“…Dietary restriction is well known to increase the life span of a variety of organisms from yeast to mammals, but the relationships between nutrition and the…”
Get full text
Journal Article -
3
Hypoxia modifies the feeding preferences of Drosophila. Consequences for diet dependent hypoxic survival
Published in BMC physiology (13-05-2010)“…Recent attention has been given to the relationships between diet, longevity, aging and resistance to various forms of stress. Flies do not simply ingest…”
Get full text
Journal Article -
4
The P2Y1 receptor is necessary for adenosine 5'-diphosphate-induced platelet aggregation
Published in Blood (01-07-1998)“…The human P2Y1 receptor heterologously expressed in Jurkat cells behaves as a specific adenosine 5'-diphosphate (ADP) receptor at which purified adenosine…”
Get full text
Journal Article -
5
ATP derivatives are antagonists of the P2Y1 receptor: similarities to the platelet ADP receptor
Published in Molecular pharmacology (01-04-1998)“…Pharmacological properties of the human P2Y1 receptor transfected in Jurkat cells and of the endogenous receptor in rat brain capillary endothelial cells were…”
Get more information
Journal Article -
6
A Natural Mutational Event Uncovers a Life History Trade-Off via Hormonal Pleiotropy
Published in Current biology (02-11-2020)“…Environmental signals often control central life history decisions, including the choice between reproduction and somatic maintenance. Such adaptive…”
Get full text
Journal Article -
7
Endothelin-1 as a mediator of endothelial cell-pericyte interactions in bovine brain capillaries
Published in Journal of cerebral blood flow and metabolism (01-04-1997)“…Endothelial cells and pericytes are closely associated in brain capillaries. Together with astrocytic foot processes, they form the blood-brain barrier…”
Get more information
Journal Article -
8
Hypoxia Up-regulates Prolyl Hydroxylase Activity
Published in The Journal of biological chemistry (03-10-2003)“…The mechanism by which hypoxia induces gene transcription is now well established. Hypoxia reduces activity of prolyl hydroxylases (PHD) that hydroxylate…”
Get full text
Journal Article -
9
Molecular mechanism of action of the vasoconstrictor peptide endothelin
Published in Biochemical and biophysical research communications (30-12-1988)“…Endothelin, one of the most potent vasoconstrictor known, has been suggested to act as an endogenous agonist of L-type Ca2+ channels. In this paper we show…”
Get more information
Journal Article -
10
Allosteric inhibition of endothelin ETA receptors by 3, 5-dibromosalicylic acid
Published in Molecular pharmacology (01-12-2000)“…Derivatives of salicylic acid (SA) and benzoic acid prevent endothelin-1 (ET-1) binding to ETA receptors. This study analyzed actions of 30 derivatives of…”
Get more information
Journal Article -
11
Aspirin and sodium salicylate inhibit endothelin ETA receptors by an allosteric type of mechanism
Published in Molecular pharmacology (01-04-2000)“…Aspirin is a commonly used drug with a wide pharmacological spectrum including antiplatelet, anti-inflammatory, and neuroprotective actions. This study shows…”
Get more information
Journal Article -
12
Targeting eIF5A Hypusination Prevents Anoxic Cell Death through Mitochondrial Silencing and Improves Kidney Transplant Outcome
Published in Journal of the American Society of Nephrology (01-03-2017)“…The eukaryotic initiation factor 5A (eIF5A), which is highly conserved throughout evolution, has the unique characteristic of post-translational activation…”
Get full text
Journal Article -
13
Food presentation modifies longevity and the beneficial action of dietary restriction in Drosophila
Published in Experimental gerontology (01-02-2010)“…Recent studies have indicated that flies respond to dilute food solutions by compensatory feeding. The existence of compensation mechanisms calls for a…”
Get full text
Journal Article -
14
Astrocytes are target cells for endothelins and sarafotoxin
Published in Journal of neurochemistry (01-06-1990)“…Endothelin-1, endothelin-3, and the snake venom toxin sarafotoxin S6b stimulate the hydrolysis of phosphatidylinositol by phospholipase C with similar…”
Get more information
Journal Article -
15
C-type natriuretic peptide is a potent activator of guanylate cyclase in endothelial cells from brain microvessels
Published in Biochemical and biophysical research communications (16-03-1992)“…An exposure of endothelial cells from rat brain microvessels to C-type natriuretic peptide (CNP) resulted in a rapid and large increase in cGMP formation. The…”
Get more information
Journal Article -
16
Food presentation modifies longevity and the beneficial action of dietary restriction in
Published in Experimental gerontology (25-01-2010)“…Recent studies have indicated that flies respond to dilute food solutions by compensatory feeding. The existence of compensation mechanisms calls for a…”
Get full text
Journal Article -
17
Diet dependent longevity and hypoxic tolerance of adult Drosophila melanogaster
Published in Mechanisms of ageing and development (01-05-2007)“…Relationships between nutrition and longevity are of growing interest. Here we analysed the influences of dietary restriction on the survival of Drosophila…”
Get full text
Journal Article -
18
The effect of PPADS as an antagonist of inositol (1,4,5)trisphosphate induced intracellular calcium mobilization
Published in British journal of pharmacology (01-09-1996)“…1 Brain capillary endothelial cells responded to uridine 5′‐triphosphate (UTP) and adenosine 5′‐triphosphate (ATP) by activation of phospholipase C and by…”
Get full text
Journal Article -
19
A single-nucleotide change underlies the genetic assimilation of a plastic trait
Published in Science advances (03-02-2021)“…Genetic assimilation-the evolutionary process by which an environmentally induced phenotype is made constitutive-represents a fundamental concept in…”
Get full text
Journal Article -
20
The role of polyamines in protein-dependent hypoxic tolerance of Drosophila
Published in BMC physiology (02-12-2008)“…Chronic hypoxia is a major component of ischemic diseases such as stroke or myocardial infarction. Drosophila is more tolerant to hypoxia than most mammalian…”
Get full text
Journal Article