Search Results - "Vigmond, Edward"

Efficient computation of electrograms and ECGs in human whole heart simulations using a reaction-eikonal model by Neic, Aurel, Campos, Fernando O., Prassl, Anton J., Niederer, Steven A., Bishop, Martin J., Vigmond, Edward J., Plank, Gernot

“…Anatomically accurate and biophysically detailed bidomain models of the human heart have proven a powerful tool for gaining quantitative insight into the links…”
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Activation signatures for identifying critical isthmi of ventricular tachyarrhythmias by Nanthakumar, Kumaraswamy, Vigmond, Edward J.

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Patient-derived models link re-entrant driver localization in atrial fibrillation to fibrosis spatial pattern by Zahid, Sohail, Cochet, Hubert, Boyle, Patrick M, Schwarz, Erica L, Whyte, Kaitlyn N, Vigmond, Edward J, Dubois, Rémi, Hocini, Mélèze, Haïssaguerre, Michel, Jaïs, Pierre, Trayanova, Natalia A

“…The mechanisms underlying persistent atrial fibrillation (AF) in patients with atrial fibrosis are poorly understood. The goal of this study was to use…”
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The ‘Digital Twin’ to enable the vision of precision cardiology by Corral-Acero, Jorge, Margara, Francesca, Marciniak, Maciej, Rodero, Cristobal, Loncaric, Filip, Feng, Yingjing, Gilbert, Andrew, Fernandes, Joao F, Bukhari, Hassaan A, Wajdan, Ali, Martinez, Manuel Villegas, Santos, Mariana Sousa, Shamohammdi, Mehrdad, Luo, Hongxing, Westphal, Philip, Leeson, Paul, DiAchille, Paolo, Gurev, Viatcheslav, Mayr, Manuel, Geris, Liesbet, Pathmanathan, Pras, Morrison, Tina, Cornelussen, Richard, Prinzen, Frits, Delhaas, Tammo, Doltra, Ada, Sitges, Marta, Vigmond, Edward J, Zacur, Ernesto, Grau, Vicente, Rodriguez, Blanca, Remme, Espen W, Niederer, Steven, Mortier, Peter, McLeod, Kristin, Potse, Mark, Pueyo, Esther, Bueno-Orovio, Alfonso, Lamata, Pablo

“…Abstract Providing therapies tailored to each patient is the vision of precision medicine, enabled by the increasing ability to capture extensive data about…”
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The role of Purkinje-myocardial coupling during ventricular arrhythmia: a modeling study by Behradfar, Elham, Nygren, Anders, Vigmond, Edward J

“…The Purkinje system is the fast conduction network of the heart which couples to the myocardium at discrete sites called Purkinje-Myocyte Junctions (PMJs)…”
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Universal ventricular coordinates: A generic framework for describing position within the heart and transferring data by Bayer, Jason, Prassl, Anton J., Pashaei, Ali, Gomez, Juan F., Frontera, Antonio, Neic, Aurel, Plank, Gernot, Vigmond, Edward J.

“…•We propose a generic set of coordinates for any heart based on anatomical landmarks.•We implemented the coordinates using solutions to Laplace’s equation.•We…”
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A publicly available virtual cohort of four-chamber heart meshes for cardiac electro-mechanics simulations by Strocchi, Marina, Augustin, Christoph M, Gsell, Matthias A F, Karabelas, Elias, Neic, Aurel, Gillette, Karli, Razeghi, Orod, Prassl, Anton J, Vigmond, Edward J, Behar, Jonathan M, Gould, Justin, Sidhu, Baldeep, Rinaldi, Christopher A, Bishop, Martin J, Plank, Gernot, Niederer, Steven A

“…Computational models of the heart are increasingly being used in the development of devices, patient diagnosis and therapy guidance. While software techniques…”
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Variability in pulmonary vein electrophysiology and fibrosis determines arrhythmia susceptibility and dynamics by Roney, Caroline H, Bayer, Jason D, Cochet, Hubert, Meo, Marianna, Dubois, Rémi, Jaïs, Pierre, Vigmond, Edward J

“…Success rates for catheter ablation of persistent atrial fibrillation patients are currently low; however, there is a subset of patients for whom electrical…”
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Universal atrial coordinates applied to visualisation, registration and construction of patient specific meshes by Roney, Caroline H., Pashaei, Ali, Meo, Marianna, Dubois, Rémi, Boyle, Patrick M., Trayanova, Natalia A., Cochet, Hubert, Niederer, Steven A., Vigmond, Edward J.

“…•We introduce a coordinate system for the atria based on anatomical landmarks.•We construct the coordinates from solutions to Laplace’s equation.•We…”
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Linking statistical shape models and simulated function in the healthy adult human heart by Rodero, Cristobal, Strocchi, Marina, Marciniak, Maciej, Longobardi, Stefano, Whitaker, John, O'Neill, Mark D, Gillette, Karli, Augustin, Christoph, Plank, Gernot, Vigmond, Edward J, Lamata, Pablo, Niederer, Steven A

“…Cardiac anatomy plays a crucial role in determining cardiac function. However, there is a poor understanding of how specific and localised anatomical changes…”
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Atrial Periodic Source Spectrum from Preoperative Body Surface Potentials Predicts Long-term Recurrence of Atrial Fibrillation by Feng, Yingjing, Dubois, Remi, Hocini, Meleze, Vigmond, Edward J.

“…Objective: About half of patients experience recurrence of atrial fibrillation (AF) within three to five years after a single catheter ablation procedure. The…”
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Simulating ventricular systolic motion in a four-chamber heart model with spatially varying robin boundary conditions to model the effect of the pericardium by Strocchi, Marina, Gsell, Matthias A.F., Augustin, Christoph M., Razeghi, Orod, Roney, Caroline H., Prassl, Anton J., Vigmond, Edward J., Behar, Jonathan M., Gould, Justin S., Rinaldi, Christopher A., Bishop, Martin J., Plank, Gernot, Niederer, Steven A.

“…The pericardium affects cardiac motion by limiting epicardial displacement normal to the surface. In computational studies, it is important for the model to…”
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The openCARP simulation environment for cardiac electrophysiology by Plank, Gernot, Loewe, Axel, Neic, Aurel, Augustin, Christoph, Huang, Yung-Lin, Gsell, Matthias A.F., Karabelas, Elias, Nothstein, Mark, Prassl, Anton J., Sánchez, Jorge, Seemann, Gunnar, Vigmond, Edward J.

“…•We present the openCARP simulation environment as a solution that could foster the needs of large parts of the computational cardiac electrophysiology…”
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Spatial Resolution Requirements for Accurate Identification of Drivers of Atrial Fibrillation by Roney, Caroline H, Cantwell, Chris D, Bayer, Jason D, Qureshi, Norman A, Lim, Phang Boon, Tweedy, Jennifer H, Kanagaratnam, Prapa, Peters, Nicholas S, Vigmond, Edward J, Ng, Fu Siong

“…Recent studies have demonstrated conflicting mechanisms underlying atrial fibrillation (AF), with the spatial resolution of data often cited as a potential…”
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Fitting membrane resistance along with action potential shape in cardiac myocytes improves convergence: application of a multi-objective parallel genetic algorithm by Kaur, Jaspreet, Nygren, Anders, Vigmond, Edward J

“…Fitting parameter sets of non-linear equations in cardiac single cell ionic models to reproduce experimental behavior is a time consuming process. The standard…”
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Propagation Failure by TRPM4 Overexpression by Gaur, Namit, Hof, Thomas, Haissaguerre, Michel, Vigmond, Edward J.

“…Transient receptor potential melastatin member 4 (TRPM4) channels are nonselective monovalent cationic channels found in human atria and conduction system…”
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Modeling our understanding of the His-Purkinje system by Vigmond, Edward J., Stuyvers, Bruno D.

“…The His-Purkinje System (HPS) is responsible for the rapid electric conduction in the ventricles. It relays electrical impulses from the atrioventricular node…”
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Modelling methodology of atrial fibrosis affects rotor dynamics and electrograms by Roney, Caroline H, Bayer, Jason D, Zahid, Sohail, Meo, Marianna, Boyle, Patrick M J, Trayanova, Natalia A, Haïssaguerre, Michel, Dubois, Rémi, Cochet, Hubert, Vigmond, Edward J

“…Catheter ablation is an effective technique for terminating atrial arrhythmia. However, given a high atrial fibrillation (AF) recurrence rate, optimal ablation…”
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How Electrode Position Affects Selective His Bundle Capture: A Modelling Study by Vigmond, Edward J., Neic, Aurel, Blauer, Joshua, Swenson, Darrell, Plank, Gernot

“…In certain cardiac conduction system pathologies, like bundle branch block, block may be proximal, allowing for electrical stimulation of the more distal His…”
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Novel Radiofrequency Ablation Strategies for Terminating Atrial Fibrillation in the Left Atrium: A Simulation Study by Bayer, Jason D, Roney, Caroline H, Pashaei, Ali, Jaïs, Pierre, Vigmond, Edward J

“…Pulmonary vein isolation (PVI) with radiofrequency ablation (RFA) is the cornerstone of atrial fibrillation (AF) therapy, but few strategies exist for when it…”
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