Search Results - "Vigili de Kreutzenberg, Saula"

Effects of Basal Insulin on Lipid Profile Compared to Other Classes of Antihyperglycemic Agents in Type 2 Diabetic Patients by Rigato, Mauro, Avogaro, Angelo, Vigili de Kreutzenberg, Saula, Fadini, Gian Paolo

“…The lipid profile represents a driver of cardiovascular risk in type 2 diabetes. The effect of chronic insulin therapy on cholesterol levels is unclear. We aim…”
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NETosis Delays Diabetic Wound Healing in Mice and Humans by Fadini, Gian Paolo, Menegazzo, Lisa, Rigato, Mauro, Scattolini, Valentina, Poncina, Nicol, Bruttocao, Andrea, Ciciliot, Stefano, Mammano, Fabio, Ciubotaru, Catalin Dacian, Brocco, Enrico, Marescotti, Maria Cristina, Cappellari, Roberta, Arrigoni, Giorgio, Millioni, Renato, Vigili de Kreutzenberg, Saula, Albiero, Mattia, Avogaro, Angelo

“…Upon activation, neutrophils undergo histone citrullination by protein arginine deiminase (PAD)4, exocytosis of chromatin and enzymes as neutrophil…”
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Diabetes Causes Bone Marrow Autonomic Neuropathy and Impairs Stem Cell Mobilization via Dysregulated p66Shc and Sirt1 by ALBIERO, Mattia, PONCINA, Nicol, AVOGARO, Angelo, FADINI, Gian Paolo, TJWA, Marc, CICILIOT, Stefano, MENEGAZZO, Lisa, CEOLOTTO, Giulio, DE KREUTZENBERG, Saula Vigili, MOURA, Rute, GIORGIO, Marco, PELICCI, Piergiuseppe

“…Diabetes compromises the bone marrow (BM) microenvironment and reduces the number of circulating CD34(+) cells. Diabetic autonomic neuropathy (DAN) may impact…”
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Diabetes Impairs Stem Cell and Proangiogenic Cell Mobilization in Humans by PAOLO FADINI, Gian, ALBIERO, Mattia, DE KREUTZENBERG, Saula Vigili, BOSCARO, Elisa, CAPPELLARI, Roberta, MARESCOTTI, Mariacristina, PONCINA, Nicol, AGOSTINI, Carlo, AVOGARO, Angelo

“…Diabetes mellitus (DM) increases cardiovascular risk, at least in part, through shortage of vascular regenerative cells derived from the bone marrow (BM). In…”
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Sex Differences in Cardiovascular Disease and Cardiovascular Risk Estimation in Patients With Type 1 Diabetes by Dei Cas, Alessandra, Aldigeri, Raffaella, Mantovani, Alessandro, Masulli, Maria, Palmisano, Luisa, Cavalot, Franco, Bonomo, Katia, Baroni, Marco Giorgio, Cossu, Efisio, Cavallo, Gisella, Cimini, Flavia Agata, Buzzetti, Raffaella, Mignogna, Carmen, Leonetti, Frida, Bacci, Simonetta, Trevisan, Roberto, Morieri, Mario Luca, Pollis, Riccardo Maria, Targher, Giovanni, Vigili de Kreutzenberg, Saula

“…Abstract Context Patients with type 1 diabetes (T1D) have higher cardiovascular disease (CVD) risk than the general population. Objective This observational…”
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Effects of the SGLT2 inhibitor dapagliflozin on cardiac function evaluated by impedance cardiography in patients with type 2 diabetes. Secondary analysis of a randomized placebo-controlled trial by Bonora, Benedetta Maria, Vigili de Kreutzenberg, Saula, Avogaro, Angelo, Fadini, Gian Paolo

“…Cardiovascular outcome trials have documented a strong benefit of sodium glucose cotransporter-2 inhibitors (SGLT2i) on the risk of hospitalization for heart…”
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Pro-inflammatory monocyte-macrophage polarization imbalance in human hypercholesterolemia and atherosclerosis by Fadini, Gian Paolo, Simoni, Francesco, Cappellari, Roberta, Vitturi, Nicola, Galasso, Silvia, Vigili de Kreutzenberg, Saula, Previato, Lorenzo, Avogaro, Angelo

“…Abstract Monocyte-macrophages (MoMas) play a major role in atherosclerosis. In mice, hypercholesterolemia increases pro-inflammatory monocytes that promote…”
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Number and Function of Endothelial Progenitor Cells as a Marker of Severity for Diabetic Vasculopathy by Fadini, Gian Paolo, Sartore, Saverio, Albiero, Mattia, Baesso, Ilenia, Murphy, Ellen, Menegolo, Mirko, Grego, Franco, de Kreutzenberg, Saula Vigili, Tiengo, Antonio, Agostini, Carlo, Avogaro, Angelo

“…OBJECTIVE—Peripheral arterial disease (PAD) is a threatening complication of diabetes. As endothelial progenitor cells (EPCs) are involved in neovasculogenesis…”
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Circulating CD34+ cells, metabolic syndrome, and cardiovascular risk by FADINI, Gian Paolo, DE KREUTZENBERG, Saula Vigili, CORACINA, Anna, BAESSO, Ilenia, AGOSTINI, Carlo, TIENGO, Antonio, AVOGARO, Angelo

“…Circulating progenitor cells are believed to participate in cardiovascular (CV) homeostasis and their exhaustion has been linked to CV damage. As general…”
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Circulating Endothelial Progenitor Cells Are Reduced in Peripheral Vascular Complications of Type 2 Diabetes Mellitus by Fadini, Gian Paolo, Miorin, Marta, Facco, Monica, Bonamico, Sondra, Baesso, Ilenia, Grego, Franco, Menegolo, Mirko, de Kreutzenberg, Saula Vigili, Tiengo, Antonio, Agostini, Carlo, Avogaro, Angelo

“…We sought to establish whether a reduction in endothelial progenitor cells (EPCs) has a putative role in peripheral vascular disease (PVD) of type 2 diabetic…”
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Intraclass differences in the risk of hospitalization for heart failure among patients with type 2 diabetes initiating a dipeptidyl peptidase‐4 inhibitor or a sulphonylurea: Results from the OsMed Health‐DB registry by Fadini, Gian Paolo, Saragoni, Stefania, Russo, Pierluigi, Degli Esposti, Luca, Vigili de Kreutzenberg, Saula, Melazzini, Mario, Avogaro, Angelo

“…Aims To re‐analyse data from a previous retrospective study on 127 555 patients, in which we showed that dipeptidyl peptidase‐4 (DPP‐4) inhibitor therapy was…”
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Peripheral blood CD34+KDR+ endothelial progenitor cells are determinants of subclinical atherosclerosis in a middle-aged general population by FADINI, Gian Paolo, CORACINA, Anna, BAESSO, Ilenia, AGOSTINI, Carlo, TIENGO, Antonio, AVOGARO, Angelo, VIGILI DE KREUTZENBERG, Saula

“…Disruption of the endothelial layer is the first step in the atherogenic process. Experimental studies have shown that endothelial progenitor cells (EPCs) are…”
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Hypovitaminosis D is associated with erectile dysfunction in type 2 diabetes by Caretta, Nicola, de Kreutzenberg, Saula Vigili, Valente, Umberto, Guarneri, Gabriella, Ferlin, Alberto, Avogaro, Angelo, Foresta, Carlo

“…Diabetes is an established risk factor for erectile dysfunction (ED). The pathophysiology of ED in diabetic men is multifactorial, but it mainly involves a…”
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Widespread Increase in Myeloid Calcifying Cells Contributes to Ectopic Vascular Calcification in Type 2 Diabetes by Fadini, Gian Paolo, Albiero, Mattia, Menegazzo, Lisa, Boscaro, Elisa, Vigili de Kreutzenberg, Saula, Agostini, Carlo, Cabrelle, Anna, Binotto, Gianni, Rattazzi, Marcello, Bertacco, Elisa, Bertorelle, Roberta, Biasini, Lorena, Mion, Monica, Plebani, Mario, Ceolotto, Giulio, Angelini, Annalisa, Castellani, Chiara, Menegolo, Mirko, Grego, Franco, Dimmeler, Stefanie, Seeger, Florian, Zeiher, Andreas, Tiengo, Antonio, Avogaro, Angelo

“…RATIONALE:Acquisition of a procalcific phenotype by resident or circulating cells is important for calcification of atherosclerotic plaques, which is common in…”
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Silent coronary artery disease in type 2 diabetes: a narrative review on epidemiology, risk factors, and clinical studies by Vigili de Kreutzenberg, Saula

“…Silent coronary artery disease (CAD) is one of the manifestations of heart disease that particularly affects subjects with type 2 diabetes mellitus (T2DM)…”
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Prevalence of orthorexic traits in type 2 diabetes mellitus: at the crossroads between nutritional counseling and eating disorders by Barbanti, Francesca Alessandra, Trento, Marina, Bruno, Graziella, Bonadonna, Riccardo, Croci, Marina, D’Eusebio, Chiara, Dei Cas, Alessandra, Invitti, Cecilia, Merlo, Fabio, Pontiroli, Antonio E., Veronelli, Anna, Vigili de Kreutzenberg, Saula, Marchesini, Giulio, Petroni, Maria Letizia

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Effects of Age, Diabetes, and Vascular Disease on Growth Differentiation Factor 11: First-in-Human Study by Fadini, Gian Paolo, Menegazzo, Lisa, Bonora, Benedetta Maria, Mazzucato, Marta, Persano, Sara, Vigili de Kreutzenberg, Saula, Avogaro, Angelo

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Improved long-term cardiovascular outcomes after intensive versus standard screening of diabetic complications: an observational study by Morieri, Mario Luca, Longato, Enrico, Mazzucato, Marta, Di Camillo, Barbara, Cocchiglia, Arianna, Gubian, Lorenzo, Sparacino, Giovanni, Avogaro, Angelo, Fadini, Gian Paolo, Vigili de Kreutzenberg, Saula

“…Complication screening is recommended for patients with type 2 diabetes (T2D), but the optimal screening intensity and schedules are unknown. In this study, we…”
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Persistent Reduction of Circulating Myeloid Calcifying Cells in Acromegaly: Relevance to the Bone–Vascular Axis by Fadini, Gian Paolo, Dassie, Francesca, Cappellari, Roberta, Persano, Mariasara, Vigili de Kreutzenberg, Saula, Martini, Chiara, Parolin, Matteo, Avogaro, Angelo, Vettor, Roberto, Maffei, Pietro

“…Acromegaly is a systemic disease characterized by persistent bone pathology and excess cardiovascular mortality. Despite multiple concomitant risk factors,…”
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p66Shc gene expression in peripheral blood mononuclear cells and progression of diabetic complications by Fadini, Gian Paolo, Albiero, Mattia, Bonora, Benedetta Maria, Poncina, Nicol, Vigili de Kreutzenberg, Saula, Avogaro, Angelo

“…The risk of diabetic complications is modified by genetic and epigenetic factors. p66Shc drives the hyperglycaemic cell damage and its deletion prevents…”
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