Search Results - "Viggers, J.A."

[ 3H]Nisoxetine—A radioligand for noradrenaline reuptake sites: Correlation with inhibition of [ 3H]noradrenaline uptake and effect of DSP-4 lesioning and antidepressant treatments by Cheetham, S.C., Viggers, J.A., Butler, S.A., Prow, M.R., Heal, D.J.

“…Nisoxetine is a potent and selective inhibitor of noradrenaline uptake into noradrenergic neurones. [ 3H]Nisoxetine binding to rat frontal cortical membranes…”
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[3H]paroxetine binding in rat frontal cortex strongly correlates with [3H]5-HT uptake: effect of administration of various antidepressant treatments by Cheetham, S C, Viggers, J A, Slater, N A, Heal, D J, Buckett, W R

“…Paroxetine is a selective and potent inhibitor of 5-hydroxytryptamine (5-HT) uptake into serotonergic neurones. [3H]Paroxetine binding to rat frontal cortex…”
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Sibutramine does not decrease the number of 5-HT re-uptake sites in rat brain and, like fluoxetine, protects against the deficits produced by dexfenfluramine by Cheetham, S.C, Viggers, J.A, Slater, N.A, Heal, D.J

“…The effect of sibutramine and dexfenfluramine on 5-HT re-uptake sites, labelled with [ 3H]paroxetine, have been determined in various rat brain regions. In…”
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