Search Results - "Viggars, Mark R."
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Skeletal muscle BMAL1 is necessary for transcriptional adaptation of local and peripheral tissues in response to endurance exercise training
Published in Molecular metabolism (Germany) (01-08-2024)“…In this investigation, we addressed the contribution of the core circadian clock factor, BMAL1, in skeletal muscle to both acute transcriptional responses to…”
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Comparative transcriptomics of broad‐spectrum and synthetic cannabidiol treated C2C12 skeletal myotubes
Published in Physiological reports (01-09-2024)“…Cannabidiol (CBD) is widely used in sports for recovery, pain management, and sleep improvement, yet its effects on muscle are not well understood. This study…”
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Automated cross-sectional analysis of trained, severely atrophied, and recovering rat skeletal muscles using MyoVision 2.0
Published in Journal of applied physiology (1985) (01-03-2022)“…The number of myonuclei within a muscle fiber is an important factor in muscle growth, but its regulation during muscle adaptation is not well understood. We…”
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Metabolism and exercise: the skeletal muscle clock takes centre stage
Published in Nature reviews. Endocrinology (01-05-2023)“…Circadian rhythms that influence mammalian homeostasis and overall health have received increasing interest over the past two decades. The molecular clock,…”
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Tendinopathy: A 'timely' matter
Published in The Journal of physiology (15-03-2023)Get full text
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Conserved and species‐specific transcriptional responses to daily programmed resistance exercise in rat and mouse
Published in The FASEB journal (01-12-2023)“…Mice are often used in gain or loss of function studies to understand how genes regulate metabolism and adaptation to exercise in skeletal muscle. Once‐daily…”
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Adaptation of the transcriptional response to resistance exercise over 4 weeks of daily training
Published in The FASEB journal (01-01-2023)“…We present the time course of change in the muscle transcriptome 1 h after the last exercise bout of a daily resistance training program lasting 2, 10, 20, or…”
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PCM1 labeling reveals myonuclear and nuclear dynamics in skeletal muscle across species
Published in American Journal of Physiology: Cell Physiology (01-01-2023)“…Myonuclei transcriptionally regulate muscle fibers during homeostasis and adaptation to exercise. Their subcellular location and quantity are important when…”
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Targeted Bmal1 restoration in muscle prolongs lifespan with systemic health effects in aging model
Published in JCI insight (01-10-2024)“…Disruption of the circadian clock in skeletal muscle worsens local and systemic health, leading to decreased muscle strength, metabolic dysfunction, and…”
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Exploring Circadian Changes in Muscle Physiology: Methodological Considerations
Published in Function (Oxford, England) (03-09-2024)Get full text
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Comparative transcriptomics of broad‐spectrum and synthetic cannabidiol treated C 2 C 12 skeletal myotubes
Published in Physiological reports (01-09-2024)“…Cannabidiol (CBD) is widely used in sports for recovery, pain management, and sleep improvement, yet its effects on muscle are not well understood. This study…”
Get full text
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