Search Results - "Vieira, Plínio Salmazo"
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Pyrrole-indolinone SU11652 targets the nucleoside diphosphate kinase from Leishmania parasites
Published in Biochemical and biophysical research communications (01-07-2017)“…Nucleoside diphosphate kinases (NDKs) are key enzymes in the purine-salvage pathway of trypanosomatids and have been associated with the maintenance of…”
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Label-free offline versus online activity methods for nucleoside diphosphate kinase b using high performance liquid chromatography
Published in Analyst (London) (07-08-2016)“…Nucleoside diphosphate kinase from Leishmania spp. (LmNDKb) has recently been described as a potential drug target to treat leishmaniasis disease. Therefore,…”
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Identification of a cold-adapted and metal-stimulated β-1,4-glucanase with potential use in the extraction of bioactive compounds from plants
Published in International journal of biological macromolecules (01-01-2021)“…Cold-adapted endo-β-1,4-glucanases hold great potential for industrial processes requiring high activity at mild temperatures such as in food processing and…”
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Crystal structure of a novel xylose isomerase from Streptomyces sp. F-1 revealed the presence of unique features that differ from conventional classes
Published in Biochimica et biophysica acta. General subjects (01-05-2020)“…Enzymatic isomerization is a promising strategy to solve the problem of xylose fermentation and, consequently, to leverage the production of advanced biofuels…”
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The role of the C-terminus and Kpn loop in the quaternary structure stability of nucleoside diphosphate kinase from Leishmania parasites
Published in Journal of structural biology (01-12-2015)“…Nucleoside diphosphate kinase (NDK) is a housekeeping enzyme that plays key roles in nucleotide recycling and homeostasis in trypanosomatids. Moreover, it is…”
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A functionally augmented carbohydrate utilization locus from herbivore gut microbiota fueled by dietary β-glucans
Published in NPJ biofilms and microbiomes (14-10-2024)“…Gut microbiota members from the Bacteroidota phylum play a pivotal role in mammalian health and metabolism. They thrive in this diverse ecosystem due to their…”
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Crystal structure and biophysical characterization of the nucleoside diphosphate kinase from Leishmania braziliensis
Published in BMC structural biology (03-02-2015)“…Nucleoside diphosphate kinase (NDK) is a housekeeping enzyme that plays key roles in nucleotide recycling and homeostasis in trypanosomatids. It is also…”
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Structural basis of exo-β-mannanase activity in the GH2 family
Published in The Journal of biological chemistry (31-08-2018)“…The classical microbial strategy for depolymerization of β-mannan polysaccharides involves the synergistic action of at least two enzymes,…”
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Production, purification, crystallization and preliminary X-ray diffraction studies of the nucleoside diphosphate kinase b from Leishmania major
Published in Acta crystallographica. Section F, Structural biology and crystallization communications (01-11-2009)“…Nucleoside diphosphate kinases (NDKs; EC 2.7.4.6) play an essential role in the synthesis of nucleotides from intermediates in the salvage pathway in all…”
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