Search Results - "Vieira, Philip A."

GLT-1-Dependent Disruption of CNS Glutamate Homeostasis and Neuronal Function by the Protozoan Parasite Toxoplasma gondii by David, Clément N, Frias, Elma S, Szu, Jenny I, Vieira, Philip A, Hubbard, Jacqueline A, Lovelace, Jonathan, Michael, Marena, Worth, Danielle, McGovern, Kathryn E, Ethell, Iryna M, Stanley, B Glenn, Korzus, Edward, Fiacco, Todd A, Binder, Devin K, Wilson, Emma H

“…The immune privileged nature of the CNS can make it vulnerable to chronic and latent infections. Little is known about the effects of lifelong brain…”
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Ultra-High-Precision, in-vivo Pharmacokinetic Measurements Highlight the Need for and a Route Toward More Highly Personalized Medicine by Vieira, Philip A, Shin, Christina B, Arroyo-Currás, Netzahualcóyotl, Ortega, Gabriel, Li, Weiwei, Keller, Arturo A, Plaxco, Kevin W, Kippin, Tod E

“…Clinical drug dosing would, ideally, be informed by high-precision, patient-specific data on drug metabolism. The direct determination of patient-specific drug…”
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Real-time measurement of small molecules directly in awake, ambulatory animals by Arroyo-Currás, Netzahualcóyotl, Somerson, Jacob, Vieira, Philip A., Ploense, Kyle L., Kippin, Tod E., Plaxco, Kevin W.

“…The development of a technology capable of tracking the levels of drugs, metabolites, and biomarkers in the body continuously and in real time would advance…”
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Nuclease Hydrolysis Does Not Drive the Rapid Signaling Decay of DNA Aptamer-Based Electrochemical Sensors in Biological Fluids by Shaver, Alexander, Kundu, Nandini, Young, Brian E, Vieira, Philip A, Sczepanski, Jonathan T, Arroyo-Currás, Netzahualcóyotl

“…Electrochemical aptamer-based (E-AB) sensors are a technology capable of real-time monitoring of drug concentrations directly in the body. These sensors…”
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A Biomimetic Phosphatidylcholine‐Terminated Monolayer Greatly Improves the In Vivo Performance of Electrochemical Aptamer‐Based Sensors by Li, Hui, Dauphin‐Ducharme, Philippe, Arroyo‐Currás, Netzahualcóyotl, Tran, Claire H., Vieira, Philip A., Li, Shaoguang, Shin, Christina, Somerson, Jacob, Kippin, Tod E., Plaxco, Kevin W.

“…The real‐time monitoring of specific analytes in situ in the living body would greatly advance our understanding of physiology and the development of…”
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CBP-Dependent memory consolidation in the prefrontal cortex supports object-location learning by Vieira, Philip A., Korzus, Edward

“…ABSTRACT Recognition of an object's location in space is supported by hippocampus‐dependent recollection. Converging evidence strongly suggests that the…”
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Correction to “Nuclease Hydrolysis Does Not Drive the Rapid Signaling Decay of DNA Aptamer-Based Electrochemical Sensors in Biological Fluids” by Shaver, Alexander, Kundu, Nandini, Young, Brian E., Vieira, Philip A., Sczepanski, Jonathan T., Arroyo-Currás, Netzahualcóyotl

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An animal model of female adolescent cannabinoid exposure elicits a long-lasting deficit in presynaptic long-term plasticity by Lovelace, Jonathan W., Corches, Alex, Vieira, Philip A., Hiroto, Alex S., Mackie, Ken, Korzus, Edward

“…Cannabis continues to be the most accessible and popular illicit recreational drug. Whereas current data link adolescence cannabinoid exposure to increased…”
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Prefrontal NMDA receptors expressed in excitatory neurons control fear discrimination and fear extinction by Vieira, Philip A., Corches, Alex, Lovelace, Jonathan W., Westbrook, Kevin B., Mendoza, Michael, Korzus, Edward

“…N-methyl-D-aspartate receptors (NMDARs) are critically involved in various learning mechanisms including modulation of fear memory, brain development and brain…”
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Endogenous glutamate within the prelimbic and infralimbic cortices regulates the incubation of cocaine-seeking in rats by Shin, Christina B., Templeton, Taylor J., Chiu, Alvin S., Kim, Jennifer, Gable, Ellen S., Vieira, Philip A., Kippin, Tod E., Szumlinski, Karen K.

“…The incubation of cue-reinforced cocaine-seeking coincides with increased extracellular glutamate within the ventromedial prefrontal cortex (vmPFC). The vmPFC…”
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Impaired Fear Memory Specificity Associated with Deficient Endocannabinoid-Dependent Long-Term Plasticity by LOVELACE, Jonathan W, VIEIRA, Philip A, CORCHES, Alex, MACKIE, Ken, KORZUS, Edward

“…In addition to its central role in learning and memory, N-methyl D-aspartate receptor (NMDAR)-dependent signaling regulates central glutamatergic synapse…”
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Prefrontal Consolidation Supports the Attainment of Fear Memory Accuracy by Vieira, Philip A, Lovelace, Jonathan W, Corches, Alex, Rashid, Asim J, Josselyn, Sheena A, Korzus, Edward

“…The neural mechanisms underlying the attainment of fear memory accuracy for appropriate discriminative responses to aversive and nonaversive stimuli are…”
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Cocaine craving during protracted withdrawal requires PKCε priming within vmPFC by Miller, Bailey W., Wroten, Melissa G., Sacramento, Arianne D., Silva, Hannah E., Shin, Christina B., Vieira, Philip A., Ben‐Shahar, Osnat, Kippin, Tod E., Szumlinski, Karen K.

“…In individuals with a history of drug taking, the capacity of drug‐associated cues to elicit indices of drug craving intensifies or incubates with the passage…”
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A Biomimetic Phosphatidylcholine‐Terminated Monolayer Greatly Improves the In Vivo Performance of Electrochemical Aptamer‐Based Sensors by Li, Hui, Dauphin‐Ducharme, Philippe, Arroyo‐Currás, Netzahualcóyotl, Tran, Claire H., Vieira, Philip A., Li, Shaoguang, Shin, Christina, Somerson, Jacob, Kippin, Tod E., Plaxco, Kevin W.

“…The real‐time monitoring of specific analytes in situ in the living body would greatly advance our understanding of physiology and the development of…”
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CBP-Dependent memory consolidation in the prefrontal cortex supports object-location learning: THE m PFC SUPPORTS SPATIAL RECOGNITION by Vieira, Philip A., Korzus, Edward

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High‐precision pharmacokinetic measurements in anesthetized and awake behaving animals by Vieira, Philip A., Arroyo, Netz, Shin, Christina, Ploense, Kyle, Plaxco, Kevin, Kippin, Tod

“…Abstract only…”
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Real‐time, continuous electrochemical monitoring of therapeutic drugs in vivo by Vieira, Philip A, Arroyo‐Curras, Netzahualcoyotl, Ploense, Kyle L, Somerson, Jacob, Plaxco, Kevin W, Kippin, Tod E

“…Abstract only Personalized medicine takes into account individual patient factors that impact the efficacy of pharmaceutical therapies. Measuring the…”
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Cocaine craving during protracted withdrawal requires PKC[epsi] priming within vmPFC by Miller, Bailey W, Wroten, Melissa G, Sacramento, Arianne D, Silva, Hannah E, Shin, Christina B, Vieira, Philip A, Ben-Shahar, Osnat, Kippin, Tod E, Szumlinski, Karen K

“…In individuals with a history of drug taking, the capacity of drug-associated cues to elicit indices of drug craving intensifies or incubates with the passage…”
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