Search Results - "Vieira, Otília V"

A Rab3a-dependent complex essential for lysosome positioning and plasma membrane repair by Encarnação, Marisa, Espada, Lília, Escrevente, Cristina, Mateus, Denisa, Ramalho, José, Michelet, Xavier, Santarino, Inês, Hsu, Victor W, Brenner, Michael B, Barral, Duarte C, Vieira, Otília V

“…Lysosome exocytosis plays a major role in resealing plasma membrane (PM) disruptions. This process involves two sequential steps. First, lysosomes are…”
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Cell Senescence, Multiple Organelle Dysfunction and Atherosclerosis by Machado-Oliveira, Gisela, Ramos, Cristiano, Marques, André R A, Vieira, Otília V

“…Atherosclerosis is an age-related disorder associated with long-term exposure to cardiovascular risk factors. The asymptomatic progression of atherosclerotic…”
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Mitochondrial Dysfunction Is the Focus of Quaternary Ammonium Surfactant Toxicity to Mammalian Epithelial Cells by INACIO, Angela S, COSTA, Gabriel N, DOMINGUES, Neuza S, SANTOS, Maria S, MORENO, António J. M, VAZ, Winchil L. C, VIEIRA, Otília V

“…Classifications Services AAC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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In vitro surfactant structure-toxicity relationships: implications for surfactant use in sexually transmitted infection prophylaxis and contraception by Inácio, Ângela S, Mesquita, Katia A, Baptista, Marta, Ramalho-Santos, João, Vaz, Winchil L C, Vieira, Otília V

“…The need for woman-controlled, cheap, safe, effective, easy-to-use and easy-to-store topical applications for prophylaxis against sexually transmitted…”
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Lysosome (Dys)function in Atherosclerosis-A Big Weight on the Shoulders of a Small Organelle by Marques, André R A, Ramos, Cristiano, Machado-Oliveira, Gisela, Vieira, Otília V

“…Atherosclerosis is a progressive insidious chronic disease that underlies most of the cardiovascular pathologies, including myocardial infarction and ischemic…”
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Involvement of the p62/NRF2 signal transduction pathway on erythrophagocytosis by Santarino, Inês B., Viegas, Michelle S., Domingues, Neuza S., Ribeiro, Ana M., Soares, Miguel P., Vieira, Otília V.

“…Erythrophagocytosis, the phagocytic removal of damaged red blood cells (RBC), and subsequent phagolysosome biogenesis are important processes in iron/heme…”
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Cholesteryl hemiazelate causes lysosome dysfunction impacting vascular smooth muscle cell homeostasis by Alves, Liliana S, Marques, André R A, Padrão, Nuno, Carvalho, Filomena A, Ramalho, José, Lopes, Catarina S, Soares, Maria I L, Futter, Clare E, Pinho E Melo, Teresa M V D, Santos, Nuno C, Vieira, Otília V

“…In atherosclerotic lesions, vascular smooth muscle cells (VSMCs) represent half of the foam cell population, which is characterized by an aberrant accumulation…”
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Oxidized cholesteryl ester induces exocytosis of dysfunctional lysosomes in lipidotic macrophages by Domingues, Neuza, Marques, André R. A., Calado, Rita Diogo Almeida, Ferreira, Inês S., Ramos, Cristiano, Ramalho, José, Soares, Maria I. L., Pereira, Telmo, Oliveira, Luís, Vicente, José R., Wong, Louise H., Simões, Inês C. M., Pinho e Melo, Teresa M. V. D., Peden, Andrew, Almeida, Cláudia Guimas, Futter, Clare E., Puertollano, Rosa, Vaz, Winchil L. C., Vieira, Otília V.

“…A key event in atherogenesis is the formation of lipid‐loaded macrophages, lipidotic cells, which exhibit irreversible accumulation of undigested modified…”
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Neuropeptide Y inhibits interleukin-1β-induced phagocytosis by microglial cells by Ferreira, Raquel, Santos, Tiago, Viegas, Michelle, Cortes, Luísa, Bernardino, Liliana, Vieira, Otília V, Malva, João O

“…Neuropeptide Y (NPY) is emerging as a modulator of communication between the brain and the immune system. However, in spite of increasing evidence that…”
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Cholesteryl hemiazelate identified in CVD patients causes in vitro and in vivo inflammation by Domingues, Neuza, Gaifem, Joana, Matthiesen, Rune, Saraiva, Diana P., Bento, Luís, Marques, André R.A., Soares, Maria I.L., Sampaio, Julio, Klose, Christian, Surma, Michal A., Almeida, Manuel S., Rodrigues, Gustavo, Gonçalves, Pedro Araújo, Ferreira, Jorge, e Melo, Ryan Gouveia, Pedro, Luís Mendes, Simons, Kai, Pinho e Melo, Teresa M.V.D., Cabral, M. Guadalupe, Jacinto, Antonio, Silvestre, Ricardo, Vaz, Winchil, Vieira, Otília V.

“…Oxidation of PUFAs in LDLs trapped in the arterial intima plays a critical role in atherosclerosis. Though there have been many studies on the atherogenicity…”
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In Vitro Activity of Quaternary Ammonium Surfactants against Streptococcal, Chlamydial, and Gonococcal Infective Agents by Inácio, Ângela S, Nunes, Alexandra, Milho, Catarina, Mota, Luís Jaime, Borrego, Maria J, Gomes, João P, Vaz, Winchil L C, Vieira, Otília V

“…Quaternary ammonium compounds (QAC) are widely used, cheap, and chemically stable disinfectants and topical antiseptics with wide-spectrum antimicrobial…”
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A Dietary Cholesterol-Based Intestinal Inflammation Assay for Improving Drug-Discovery on Inflammatory Bowel Diseases by Silva, Nuno-Valério, Carregosa, Diogo, Gonçalves, Catarina, Vieira, Otília V., Nunes dos Santos, Cláudia, Jacinto, António, Crespo, Carolina Lage

“…Inflammatory bowel diseases (IBD) with chronic infiltration of immune cells in the gastrointestinal tract are common and largely incurable. The therapeutic…”
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Cholesteryl Hemiazelate Present in Cardiovascular Disease Patients Causes Lysosome Dysfunction in Murine Fibroblasts by Lopes, Elizeth, Machado-Oliveira, Gisela, Simões, Catarina Guerreiro, Ferreira, Inês S, Ramos, Cristiano, Ramalho, José, Soares, Maria I L, Melo, Teresa M V D Pinho E, Puertollano, Rosa, Marques, André R A, Vieira, Otília V

“…There is growing evidence supporting the role of fibroblasts in all stages of atherosclerosis, from the initial phase to fibrous cap and plaque formation. In…”
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Maturation of phagosomes containing different erythrophagocytic particles in primary macrophages by Santarino, Inês B., Vieira, Otília V.

“…Erythrophagocytosis is a physiological process that aims to remove damaged red blood cells from the circulation in order to avoid hemolysis and uncontrolled…”
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Cholesteryl hemiesters alter lysosome structure and function and induce proinflammatory cytokine production in macrophages by Domingues, Neuza, Estronca, Luís M.B.B., Silva, João, Encarnação, Marisa R., Mateus, Rita, Silva, Diogo, Santarino, Inês B., Saraiva, Margarida, Soares, Maria I.L., Pinho e Melo, Teresa M.V.D., Jacinto, António, Vaz, Winchil L.C., Vieira, Otília V.

“…Cholesteryl hemiesters are oxidation products of polyunsaturated fatty acid esters of cholesterol. Their oxo-ester precursors have been identified as important…”
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Comparison of the kinetics of maturation of phagosomes containing apoptotic cells and IgG-opsonized particles by Viegas, Michelle S, Estronca, Luís M B B, Vieira, Otília V

“…Defective clearance of apoptotic cells has emerged as an important contributing factor to the pathogenesis of many diseases. Although many efforts have been…”
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Overexpression of BDNF and Full-Length TrkB Receptor Ameliorate Striatal Neural Survival in Huntington's Disease by Silva, Ana, Naia, Luana, Dominguez, Alejandro, Ribeiro, Márcio, Rodrigues, Joana, Vieira, Otília V, Lessmann, Volkmar, Rego, Ana Cristina

“…Several cellular mechanisms have been proposed to explain the pathogenesis of Huntington's disease (HD), including the lack of striatal brain-derived…”
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Delay of EGF-Stimulated EGFR Degradation in Myotonic Dystrophy Type 1 (DM1) by Alegre-Cortés, Eva, Giménez-Bejarano, Alberto, Uribe-Carretero, Elisabet, Paredes-Barquero, Marta, Marques, André R. A, Lopes-da-Silva, Mafalda, Vieira, Otília V, Canales-Cortés, Saray, Camello, Pedro J, Martínez-Chacón, Guadalupe, Aiastui, Ana, Fernández-Torrón, Roberto, López de Munain, Adolfo, Gomez-Suaga, Patricia, Niso-Santano, Mireia, González-Polo, Rosa A, Fuentes, José M, Yakhine-Diop, Sokhna M. S

“…Myotonic dystrophy type 1 (DM1) is an autosomal dominant disease caused by a CTG repeat expansion in the 3′ untranslated region of the dystrophia myotonica…”
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Quaternary ammonium surfactant structure determines selective toxicity towards bacteria: mechanisms of action and clinical implications in antibacterial prophylaxis by Inácio, Ângela S, Domingues, Neuza S, Nunes, Alexandra, Martins, Patrícia T, Moreno, Maria J, Estronca, Luís M, Fernandes, Rui, Moreno, António J M, Borrego, Maria J, Gomes, João P, Vaz, Winchil L C, Vieira, Otília V

“…Broad-spectrum antimicrobial activity of quaternary ammonium surfactants (QAS) makes them attractive and cheap topical prophylactic options for sexually…”
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Lipid and Non-lipid Factors Affecting Macrophage Dysfunction and Inflammation in Atherosclerosis by Gibson, Mark S, Domingues, Neuza, Vieira, Otilia V

“…Atherosclerosis is a chronic inflammatory disease and a leading cause of human mortality. The lesional microenvironment contains a complex accumulation of…”
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