Search Results - "Videlock, Elizabeth"
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Association Between Early Adverse Life Events and Irritable Bowel Syndrome
Published in Clinical gastroenterology and hepatology (01-04-2012)“…Background & Aims Although childhood and adult abuse are more prevalent among patients with irritable bowel syndrome (IBS) than healthy individuals (controls),…”
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Latest Insights on the Pathogenesis of Irritable Bowel Syndrome
Published in Gastroenterology clinics of North America (01-09-2021)“…The pathogenesis of irritable bowel syndrome is multifactorial and complex. Our understanding of its pathophysiology has evolved, but remains incompletely…”
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Effects of Linaclotide in Patients With Irritable Bowel Syndrome With Constipation or Chronic Constipation: A Meta-analysis
Published in Clinical gastroenterology and hepatology (01-09-2013)“…Background & Aims Linaclotide is a minimally absorbed, 14-amino acid peptide used to treat patients with irritable bowel syndrome with constipation (IBS-C) or…”
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Childhood Trauma Is Associated With Hypothalamic-Pituitary-Adrenal Axis Responsiveness in Irritable Bowel Syndrome
Published in Gastroenterology (New York, N.Y. 1943) (01-12-2009)“…Background & Aims A history of early adverse life events (EALs) is associated with a poorer outcome and higher levels of distress in adult patients with…”
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Risk Factors for Abdominal Pain–Related Disorders of Gut–Brain Interaction in Adults and Children: A Systematic Review
Published in Gastroenterology (New York, N.Y. 1943) (01-10-2022)“…BACKGROUND & AIMSMany studies have assessed risk factors of irritable bowel syndrome (IBS) and other abdominal pain-related disorders of gut-brain interaction…”
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Experimental models of gut‐first Parkinson's disease: A systematic review
Published in Neurogastroenterology and motility (01-08-2023)“…Background There is strong support from studies in humans and in animal models that Parkinson's disease (PD) may begin in the gut. This brings about a unique…”
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Negative Events During Adulthood Are Associated With Symptom Severity and Altered Stress Response in Patients With Irritable Bowel Syndrome
Published in Clinical gastroenterology and hepatology (01-10-2019)“…Irritable bowel syndrome (IBS) is a stress-sensitive disorder associated with dysregulation of the hypothalamic–pituitary–adrenal axis. We studied the…”
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Sigmoid colon mucosal gene expression supports alterations of neuronal signaling in irritable bowel syndrome with constipation
Published in American journal of physiology: Gastrointestinal and liver physiology (01-07-2018)“…Peripheral factors likely play a role in at least a subset of irritable bowel syndrome (IBS) patients. Few studies have investigated mucosal gene expression…”
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Serum and Colonic Mucosal Immune Markers in Irritable Bowel Syndrome
Published in The American journal of gastroenterology (01-02-2012)“…Low-grade colonic mucosal inflammation has been postulated to have an important role in the pathophysiology of irritable bowel syndrome (IBS). The objectives…”
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Importance of trauma‐related fear in patients with irritable bowel syndrome and early adverse life events
Published in Neurogastroenterology and motility (01-09-2020)“…Background Although early adverse life events (EALs) are prevalent among patients with irritable bowel syndrome (IBS), the impact of fear or dissociation…”
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Use Of Weighted Gene Coexpression Network Analysis To Identify Connectivity Between Gut And Brain Gene Expression
Published in The FASEB journal (01-05-2022)“…Background Alterations in the gut brain axis are being recognized as a pathogenic factor for an increasing number of diseases, including neurodegenerative…”
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The effect of sex and irritable bowel syndrome on HPA axis response and peripheral glucocorticoid receptor expression
Published in Psychoneuroendocrinology (01-07-2016)“…Highlights • Cortisol response to ACTH is affected by sex and irritable bowel syndrome (IBS). • Response is increased in men but blunted in women with IBS…”
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Probiotics for Antibiotic-Associated Diarrhea
Published in JAMA : the journal of the American Medical Association (15-08-2012)Get full text
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Tu1799 Differences in Cortisol Responses to Hormone Challenge vs. Visceral Stressor in Irritable Bowel Syndrome
Published in Gastroenterology (New York, N.Y. 1943) (01-04-2016)Get full text
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Dysregulation of the Long-Noncoding RNA, Ghrlos, in Irritable Bowel Syndrome
Published in Gastroenterology (New York, N.Y. 1943) (01-04-2017)Get full text
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Expression Profiling of Sigmoid Biopsies in Irritable Bowel Syndrome vs Healthy Controls
Published in Gastroenterology (New York, N.Y. 1943) (01-04-2017)Get full text
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Loss of miR-24-3p promotes epithelial cell apoptosis and impairs the recovery from intestinal inflammation
Published in Cell death & disease (18-12-2021)“…While apoptosis plays a significant role in intestinal homeostasis, it can also be pathogenic if overactive during recovery from inflammation. We recently…”
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Stress hormones and post-traumatic stress disorder in civilian trauma victims: a longitudinal study. Part I: HPA axis responses
Published in The international journal of neuropsychopharmacology (01-05-2008)“…The aim of the study was to evaluate the association between post-traumatic disorder (PTSD) and hypothalamic–pituitary–adrenal (HPA) axis responses to the…”
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Distinct Patterns of Gene Expression Changes in the Colon and Striatum of Young Mice Overexpressing Alpha-Synuclein Support Parkinson’s Disease as a Multi-System Process
Published in Journal of Parkinson's disease (01-01-2023)“…Background: Evidence supports a role for the gut-brain axis in Parkinson’s disease (PD). Mice overexpressing human wild type α– synuclein (Thy1-haSyn) exhibit…”
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