Search Results - "Videira, Romeu"

Carbon Nanomaterials with SOD-like Activity: The Effect of the Ionic Strength by Veloso, Andreia D, Videira, Romeu A, Oliveira, Maria C

“…Electrogenerated hydrophilic carbon (EHC) nanomaterials emerge as a highly attractive option for mimicking the activity of the superoxide dismutase enzyme…”
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Topical fixed-dose combinations: Current in vitro methodologies for pre-clinical development by Veloso, Cláudia, Videira, Romeu A, Andrade, Paula B., Cardoso, Catarina, Vitorino, Carla

“…[Display omitted] The combination of two or more active pharmaceutical ingredients in the same dosage form - fixed-dose combination products - for topical…”
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Extraction of phospholipid-rich fractions from egg yolk and development of liposomes entrapping a dietary polyphenol with neuroactive potential by Bernardo, João, Videira, Romeu A., Valentão, Patrícia, Veiga, Francisco, Andrade, Paula B.

“…A new protocol to obtain egg yolk phospholipids in ethanol is presented. Rutin-phospholipids nanoliposomes were prepared and characterized. The procedure takes…”
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Mitochondrial Dysfunction in Skeletal Muscle of Rotenone-Induced Rat Model of Parkinson's Disease: SC- Nanophytosomes as Therapeutic Approach by Mendes, Daniela, Peixoto, Francisco, Oliveira, Maria Manuel, Andrade, Paula Branquinho, Videira, Romeu António

“…The development of new therapeutic options for Parkinson's disease (PD) requires formulations able to mitigate both brain degeneration and motor dysfunctions…”
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In vivo methodologies to assist preclinical development of topical fixed-dose combinations for pain management by Veloso, Cláudia, Videira, Romeu A., Andrade, Paula B., Cardoso, Catarina, Vitorino, Carla

“…[Display omitted] The combination in a fixed dose of two or more active pharmaceutical ingredients in the same pharmaceutical dosage form is an approach that…”
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Exploring the bioactive potential of algae residue extract via subcritical water extraction: Insights into chemical composition and biological activity by Trigueros, Esther, Oliveira, Andreia P., Andrade, Paula B., Videira, Romeu A., de Pinho, Paula Guedes, Sanz, M. Teresa, Beltrán, Sagrario

“…Gelidium sesquipedale is valued in the Spanish agar industry, but its production generates substantial waste, often discarded despite its nutritional and…”
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Cardiolipin profile changes are associated to the early synaptic mitochondrial dysfunction in Alzheimer's disease by Monteiro-Cardoso, Vera F, Oliveira, M Manuel, Melo, Tânia, Domingues, Maria R M, Moreira, Paula I, Ferreiro, Elisabete, Peixoto, Francisco, Videira, Romeu A

“…Brain mitochondria are fundamental to maintaining healthy functional brains, and their dysfunction is involved in age-related neurodegenerative disorders such…”
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Trichilia catigua and Turnera diffusa phyto-phospholipid nanostructures: Physicochemical characterization and bioactivity in cellular models of induced neuroinflammation and neurotoxicity by Bernardo, João, Santos, Ana Cláudia, Videira, Romeu A., Valentão, Patrícia, Veiga, Francisco, Andrade, Paula B.

“…[Display omitted] Flavonoid-based therapies supported by nanotechnology are considered valuable strategies to prevent or delay age-related and chronic…”
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A nanophytosomes formulation based on elderberry anthocyanins and Codium lipids to mitigate mitochondrial dysfunctions by Mendes, Daniela, Valentão, Patrícia, Oliveira, Maria Manuel, Andrade, Paula, Videira, Romeu A.

“…The development of nanomedicines to modulate the mitochondrial function is a great scientific challenge since mitochondrial dysfunction is a pathological…”
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Brain Effects of SC-Nanophytosomes on a Rotenone-Induced Rat Model of Parkinson’s Disease—A Proof of Concept for a Mitochondria-Targeted Therapy by Mendes, Daniela, Peixoto, Francisco, Oliveira, Maria Manuel, Andrade, Paula Branquinho, Videira, Romeu António

“…Mitochondria are an attractive target to fight neurodegenerative diseases due to their important functions for cells and the particularly close relationship…”
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Adding value to polyvinylpolypyrrolidone winery residue: A resource of polyphenols with neuroprotective effects and ability to modulate type 2 diabetes-relevant enzymes by Rocha, Lídia, Neves, Dina, Valentão, Patrícia, Andrade, Paula B., Videira, Romeu A.

“…•Polyphenol-rich extract was obtained from PVPP winery residue.•PVPP-white wine extract has remarkable antioxidant activity.•Inhibition of α-glucosidase and…”
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Trichilia catigua and Turnera diffusa extracts: In vitro inhibition of tyrosinase, antiglycation activity and effects on enzymes and pathways engaged in the neuroinflammatory process by Bernardo, João, Malheiro, Inês, Videira, Romeu A., Valentão, Patrícia, Santos, Ana Cláudia, Veiga, Francisco, Andrade, Paula B.

“…Flavonoids interact with multiple targets in Central Nervous System resulting in a broad neuroprotection mediated by complementary processes and synergic…”
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Diet during early life defines testicular lipid content and sperm quality in adulthood by Crisóstomo, Luís, Videira, Romeu A, Jarak, Ivana, Starčević, Kristina, Mašek, Tomislav, Rato, Luís, Raposo, João F, Batterham, Rachel L, Oliveira, Pedro F, Alves, Marco G

“…Childhood obesity is a serious concern associated with ill health later in life. Emerging data suggest that obesity has long-term adverse effects upon male…”
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Mitochondria research and neurodegenerative diseases: On the track to understanding the biological world of high complexity by Mendes, Daniela, Peixoto, Francisco, Oliveira, Maria M., Andrade, Paula B., Videira, Romeu A.

“…•The way how the emergence of mitochondria research field improved our knowledge on the hmajor metabolic pathways.•How mitochondria 3-D architecture fits with…”
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Mexican calea (Calea zacatechichi Schltdl.) interferes with cholinergic and dopaminergic pathways and causes neuroglial toxicity by Garcia, Maria Rita, Ferreres, Federico, Mineiro, Tiago, Videira, Romeu A., Gil-Izquierdo, Ángel, Andrade, Paula B., Seabra, Vítor, Dias-da-Silva, Diana, Gomes, Nelson G.M.

“…The use of “Mexican calea” (Calea zacatechichi Schltdl.) in ritualistic ceremonies, due to its dream-inducing effects, was until recently limited to indigenous…”
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Valorisation of kitul, an overlooked food plant: Phenolic profiling of fruits and inflorescences and assessment of their effects on diabetes-related targets by Ferreres, Federico, Andrade, Catarina, Gomes, Nelson G.M., Andrade, Paula B., Gil-Izquierdo, Angel, Pereira, David M., Suksungworn, Rungcharn, Duangsrisai, Sutsawat, Videira, Romeu A., Valentão, Patrícia

“…•Caffeoylquinic and caffeoylshikimic acids derivatives firstly described in kitul.•Marked inhibition of yeast and human α-glucosidase by the inflorescences’…”
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The administration of methyl and butyl parabens interferes with the enzymatic antioxidant system and induces genotoxicity in rat testis: possible relation to male infertility by Martins, Fátima C., Oliveira, M. M., Gaivão, Isabel, A. Videira, Romeu, Peixoto, Francisco

“…Parabens are esters of p-hydroxybenzoic acid, used for decades as a preservative in many products, including agrochemicals, pharmaceuticals, foods and…”
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Improving pollutants environmental risk assessment using a multi model toxicity determination with in vitro, bacterial, animal and plant model systems: The case of the herbicide alachlor by Pereira, Susana P., Santos, Sandra M.A., Fernandes, Maria A.S., Deus, Cláudia M., Martins, João D., Pedroso de Lima, Maria C., Vicente, Joaquim A.F., Videira, Romeu A., Jurado, Amália S.

“…Several environmental pollutants, including pesticides, herbicides and persistent organic pollutants play an important role in the development of chronic…”
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Inherited Metabolic Memory of High‐Fat Diet Impairs Testicular Fatty Acid Content and Sperm Parameters by Crisóstomo, Luís, Videira, Romeu A., Jarak, Ivana, Starčević, Kristina, Mašek, Tomislav, Rato, Luís, Raposo, João F., Batterham, Rachel L., Oliveira, Pedro F., Alves, Marco G.

“…Scope Exposure to a high‐fat diet (HFD) from early‐life is associated with a testicular metabolic signature link to abnormal sperm parameters up to two…”
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Anti-Inflammatory Activity of Olive Oil Polyphenols-The Role of Oleacein and Its Metabolites by Costa, Vânia, Costa, Marlene, Videira, Romeu António, Andrade, Paula Branquinho, Paiva-Martins, Fátima

“…The anti-inflammatory potential of oleacein, the main polyphenolic compound found in olive oil, and its main metabolites were characterized by their effects on…”
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