Search Results - "Vidal, Valerie I P"
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Functional analysis of Sox8 and Sox9 during sex determination in the mouse
Published in Development (Cambridge) (01-05-2004)“…Sex determination in mammals directs an initially bipotential gonad to differentiate into either a testis or an ovary. This decision is triggered by the…”
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WT1 Maintains Adrenal-Gonadal Primordium Identity and Marks a Population of AGP-like Progenitors within the Adrenal Gland
Published in Developmental cell (14-10-2013)“…Adrenal glands and gonads share a common primordium (AGP), but the molecular events driving differentiation are poorly understood. Here we demonstrate that the…”
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Steroidogenic organ development and homeostasis: A WT1-centric view
Published in Molecular and cellular endocrinology (15-06-2015)“…•The Wilms' tumor suppressor WT1 is a key regulator of adrenogonadal development.•Alternatively spliced isoforms fulfill distinct molecular and cellular…”
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SOX9 expression is a general marker of basal cell carcinoma and adnexal-related neoplasms
Published in Journal of cutaneous pathology (01-04-2008)“…Background: SOX9 is a transcription factor that fulfills multiple functions during development. In the hair follicle SOX9 is expressed in the outer layer of…”
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Sox9 induces testis development in XX transgenic mice
Published in Nature genetics (01-07-2001)“…Mutations in SOX9 are associated with male-to-female sex reversal in humans. To analyze Sox9 function during sex determination, we ectopically expressed this…”
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Sox9 Is Essential for Outer Root Sheath Differentiation and the Formation of the Hair Stem Cell Compartment
Published in Current biology (09-08-2005)“…Background: The mammalian hair represents an unparalleled model system to understand both developmental processes and stem cell biology. The hair follicle…”
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The Wilms' tumor gene Wt1 is required for normal development of the retina
Published in The EMBO journal (15-03-2002)“…The Wilms' tumor gene Wt1 is known for its important functions during genitourinary and mesothelial formation. Here we show that Wt1 is necessary for neuronal…”
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R-spondin signalling is essential for the maintenance and differentiation of mouse nephron progenitors
Published in eLife (01-05-2020)“…During kidney development, WNT/β-catenin signalling has to be tightly controlled to ensure proliferation and differentiation of nephron progenitor cells. Here,…”
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