Search Results - "Victor Dumitrascu"
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Mechanistic investigations of antitumor activity of a Rhodamine B‑oleanolic acid derivative bioconjugate
Published in Oncology reports (01-09-2020)“…Cancer remains a major health problem worldwide due to its high mortality rate. New therapeutic options highlight the importance of discovering new compounds…”
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Multidrug-Resistant Gram-Negative Bacilli: A Retrospective Study of Trends in a Tertiary Healthcare Unit
Published in Medicina (Kaunas, Lithuania) (26-11-2018)“…Bacterial multidrug resistance is particularly common in Gram-negative bacilli (GNB), with important clinical consequences regarding their spread and treatment…”
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3
Prolactin response to antipsychotics: An inpatient study
Published in PloS one (04-02-2020)“…Antipsychotic medication, stress, gender, and age are factors that influence prolactin levels in patients with psychosis. The aim of the study was to…”
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4
The rcdk and cluster R packages applied to drug candidate selection
Published in Journal of cheminformatics (20-01-2020)“…The aim of this article is to show how thevpower of statistics and cheminformatics can be combined, in R, using two packages: rcdk and cluster . We describe…”
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Mitochondrial DNA Changes in Blood and Urine Display a Specific Signature in Relation to Inflammation in Normoalbuminuric Diabetic Kidney Disease in Type 2 Diabetes Mellitus Patients
Published in International journal of molecular sciences (01-06-2023)“…Mitochondrial dysfunction is an important mechanism contributing to the development and progression of diabetic kidney disease (DKD). Mitochondrial DNA (mtDNA)…”
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Proximal tubule dysfunction is associated with podocyte damage biomarkers nephrin and vascular endothelial growth factor in type 2 diabetes mellitus patients: a cross-sectional study
Published in PloS one (14-11-2014)“…There is an ongoing debate as to whether early diabetic nephropathy in Type 2 diabetes mellitus may be attributed to the glomerulus or to the proximal tubule…”
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SARS-CoV-2 Seroprevalence in Western Romania, March to June 2021
Published in Medicina (Kaunas, Lithuania) (26-12-2021)“…The extent of SARS-CoV-2 infection among a population may be assessed by the presence of serum SARS-CoV-2 antibodies, which indicates previous exposure. The…”
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[Corrigendum] Mechanistic investigations of antitumor activity of a Rhodamine B‑oleanolic acid derivative bioconjugate
Published in Oncology reports (01-04-2021)“…Subsequently to the publication of the above paper, the authors have realized that they should have credited a Professor René Csuk [Martin‑Luther‑Universität…”
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Current State of Knowledge Regarding WHO Critical Priority Pathogens: Mechanisms of Resistance and Proposed Solutions through Candidates Such as Essential Oils
Published in Plants (Basel) (06-07-2022)“…The rise of multidrug-resistant (MDR) pathogens has become a global health threat and an economic burden in providing adequate and effective treatment for many…”
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Mitochondrial DNA and Inflammation Are Associated with Cerebral Vessel Remodeling and Early Diabetic Kidney Disease in Patients with Type 2 Diabetes Mellitus
Published in Biomolecules (Basel, Switzerland) (01-04-2024)“…Cerebrovascular disease accounts for major neurologic disabilities in patients with type 2 diabetes mellitus (DM). A potential association of mitochondrial DNA…”
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SARS-CoV-2: An Overview of the Genetic Profile and Vaccine Effectiveness of the Five Variants of Concern
Published in Pathogens (Basel) (26-04-2022)“…With the onset of the COVID-19 pandemic, enormous efforts have been made to understand the genus SARS-CoV-2. Due to the high rate of global transmission,…”
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MTHFR Gene Polymorphisms and Cardiovascular Risk Factors, Clinical-Imagistic Features and Outcome in Cerebral Venous Sinus Thrombosis
Published in Brain sciences (27-12-2020)“…Cerebral venous sinus thrombosis (CVST) as a severe neurological emergency, is represented by variable conditions in its clinic presentation, onset, risk…”
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Metabolites Potentially Derived from Gut Microbiota Associated with Podocyte, Proximal Tubule, and Renal and Cerebrovascular Endothelial Damage in Early Diabetic Kidney Disease in T2DM Patients
Published in Metabolites (28-07-2023)“…Complications due to type 2 diabetes mellitus (T2DM) such as diabetic kidney disease (DKD) and cerebral small vessel disease (CSVD) have a powerful impact on…”
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14
Urinary podocyte-associated mRNA levels correlate with proximal tubule dysfunction in early diabetic nephropathy of type 2 diabetes mellitus
Published in Diabetology and metabolic syndrome (06-05-2017)“…The study assessed mRNA expression of podocyte-associated molecules in urinary sediments of patients with type 2 diabetes mellitus (DM) in relation to urinary…”
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Extensively drug-resistant Acinetobacter baumannii and Proteeae association in a Romanian intensive care unit: risk factors for acquisition
Published in Infection and drug resistance (01-01-2018)“…The purpose of this study was to identify risk factors for extensively drug-resistant (XDR) (AB) and XDR association in the largest intensive care unit (ICU)…”
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Cystic echinococcosis in children and adults: a seven-year comparative study in western Romania
Published in Foodborne pathogens and disease (01-02-2013)“…This study aims to compare the epidemiological, clinical, and laboratory aspects of cystic echinococcosis (CE) in children with those of adults from western…”
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Targeting Mitochondria through the Use of Mitocans as Emerging Anticancer Agents
Published in Current medicinal chemistry (01-01-2020)“…Mitochondria are key players with a multi-functional role in many vital cellular processes, such as energy metabolism, redox regulation, calcium homeostasis,…”
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Selective and fast methylation of free fatty acids directly in plasma for their individual analysis by gas chromatography- mass spectrometry
Published in Journal of Chromatography A (02-08-2020)“…•Direct and selective methylation of plasma free fatty acids for GC.•Complete methyl esterification in 1 min at room temperature.•Avoid transmethylation of…”
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A rare case of renal hydatidosis in a child with congenital solitary kidney
Published in Asian Pacific journal of tropical medicine (01-08-2014)“…Hydatid cyst of a solitary congenital kidney is a rare entity because of the small percentage of cases with renal hydatidosis and the reduced number of cases…”
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Influence of rosuvastatin dose on total fatty acids and free fatty acids in plasma: Correlations with lipids involved in cholesterol homeostasis
Published in Medicine (Baltimore) (25-11-2020)“…This study investigates for the first time the influence of four doses of rosuvastatin on total fatty acids (TFA) and free fatty acids (FFA) in human plasma…”
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