Search Results - "Vicky García"
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Synthetic hydrogels for human intestinal organoid generation and colonic wound repair
Published in Nature cell biology (01-11-2017)“…In vitro differentiation of human intestinal organoids (HIOs) from pluripotent stem cells is an unparalleled system for creating complex, multicellular…”
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2
EGF Regulates Claudin-2 and -4 Expression Through Src and STAT3 in MDCK Cells
Published in Journal of cellular physiology (01-01-2015)“…Epidermal Growth Factor (EGF) is a key regulator of epithelial paracellular permeability, a property that depends on tight junctions (TJ) and can be evaluated…”
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3
Intestinal epithelial claudins: expression and regulation in homeostasis and inflammation
Published in Annals of the New York Academy of Sciences (01-06-2017)“…The intestinal epithelium forms a highly dynamic and selective barrier that controls absorption of fluid and solutes while restricting pathogen access to…”
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4
Fibrolytic activity of four Trichoderma strains grown on agro-industrial residues
Published in Revista de la Facultad de Ciencias Agrarias, Universidad Nacional de Cuyo (01-12-2019)“…The aim of this study was to compare the cellulolytic and xylanolytic activities of two strains of Trichoderma viride, one of Trichoderma reesei and one of…”
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5
TNFα promotes mucosal wound repair through enhanced platelet activating factor receptor signaling in the epithelium
Published in Mucosal immunology (01-07-2019)“…Pathobiology of several chronic inflammatory disorders, including ulcerative colitis and Crohn’s disease is related to intermittent, spontaneous…”
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Claudin-23 reshapes epithelial tight junction architecture to regulate barrier function
Published in Nature communications (05-10-2023)“…Claudin family tight junction proteins form charge- and size-selective paracellular channels that regulate epithelial barrier function. In the gastrointestinal…”
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Ouabain induces endocytosis and degradation of tight junction proteins through ERK1/2-dependent pathways
Published in Experimental cell research (01-01-2014)“…In addition to being a very well-known ion pump, Na+, K+-ATPase is a cell–cell adhesion molecule and the receptor of digitalis, which transduces regulatory…”
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8
The manganese transporter SLC39A8 links alkaline ceramidase 1 to inflammatory bowel disease
Published in Nature communications (05-06-2024)“…The metal ion transporter SLC39A8 is associated with physiological traits and diseases, including blood manganese (Mn) levels and inflammatory bowel diseases…”
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9
HPV16-E6 Oncoprotein Activates TGF-β and Wnt/β-Catenin Pathways in the Epithelium-Mesenchymal Transition of Cataracts in a Transgenic Mouse Model
Published in BioMed research international (01-01-2018)“…Objective. This work aimed to determine if cataractous changes associated with EMT occurring in the K14E6 mice lenses are associated with TGF-β and…”
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Dysregulation of intestinal epithelial CFTR-dependent Cl− ion transport and paracellular barrier function drives gastrointestinal symptoms of food-induced anaphylaxis in mice
Published in Mucosal immunology (01-01-2021)“…Food-triggered anaphylaxis can encompass a variety of systemic and intestinal symptoms. Murine-based and clinical studies have revealed a role for histamine…”
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Optimizing Silage Strategies for Sustainable Livestock Feed: Preserving Retail Food Waste
Published in Agriculture (Basel) (01-01-2024)“…In Canada, approximately 11.2 million metric tons of avoidable food waste (FW) is produced per year. Preservation of a greater proportion of this FW for use as…”
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Claudin‐23 Strengthens the Colonic Epithelial Barrier by Regulating Claudin‐3 and ‐4 proteins in the Tight Junction Plasma Membrane
Published in The FASEB journal (01-05-2022)“…Colonic epithelial barrier function is controlled by differential expression of Claudin (CLDN) proteins in the crypt‐luminal axis. We recently identified the…”
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PSXI-5 Transforming retailer’s food waste into silage for sustainable animal nutrition
Published in Journal of animal science (14-09-2024)“…Food waste (FW) represents a major environmental and socio-economic problem. In Canada, about 11.2 million metric tons of avoidable food waste is produced…”
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Assessing the methane mitigation potential of Canadian red seaweeds using in vitro batch culture
Published in Canadian journal of animal science (01-12-2023)“…Seven red Canadian seaweeds (Callophyllis flabellulata, Graciliariopsis verrucosa, Mastocarpus papillatus, Mazzaella splendens, Mazzaella japonica, Palmaria…”
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INFLAMMATION-TRIGGERED CLAUDIN-23 DOWNREGULATION IMPACTS INTESTINAL EPITHELIAL BARRIER FUNCTION
Published in Gastroenterology (New York, N.Y. 1943) (01-02-2024)Get full text
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INFLAMMATION-TRIGGERED CLAUDIN-23 DOWNREGULATION IMPACTS INTESTINAL EPITHELIAL BARRIER FUNCTION
Published in Inflammatory bowel diseases (25-01-2024)“…Intestinal epithelium maintains gut homeostasis by protecting the underlying tissue compartments from harmful contents. Although it is suggested that…”
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65 Metagenomic analysis of ensiled grocery food waste
Published in Journal of animal science (14-09-2024)“…Vegetables and fruits are the main sources of plant fiber, minerals, and vitamins essential for human health. However, commercially manufactured foods which…”
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Macrophage-derived IL-10 mediates mucosal repair by epithelial WISP-1 signaling
Published in The Journal of clinical investigation (01-09-2017)“…In response to injury, epithelial cells migrate and proliferate to cover denuded mucosal surfaces and repair the barrier defect. This process is orchestrated…”
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Desmocollin-2 promotes intestinal mucosal repair by controlling integrin-dependent cell adhesion and migration
Published in Molecular biology of the cell (15-03-2020)“…The intestinal mucosa is lined by a single layer of epithelial cells that forms a tight barrier, separating luminal antigens and microbes from underlying…”
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Regulation of intestinal epithelial intercellular adhesion and barrier function by desmosomal cadherin desmocollin-2
Published in Molecular biology of the cell (15-04-2021)“…The role of desmosomal cadherin desmocollin-2 (Dsc2) in regulating barrier function in intestinal epithelial cells (IECs) is not well understood. Here, we…”
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