Search Results - "Vickery, Rodney D"
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Discovery of the CCR1 Antagonist, BMS-817399, for the Treatment of Rheumatoid Arthritis
Published in Journal of medicinal chemistry (25-09-2014)“…High-affinity, functionally potent, urea-based antagonists of CCR1 have been discovered. Modulation of PXR transactivation has revealed the selective and…”
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Solid-state carbon NMR characterization of the polymorphs of roxifiban
Published in Journal of pharmaceutical and biomedical analysis (22-08-2002)“…Roxifiban, an experimental antithrombotic prodrug, exists as crystalline forms I and II. A quantitative solid-state nuclear magnetic resonance (NMR) method was…”
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Thermal decomposition of matrix metalloproteinase inhibitors: Evidence of solid state dimerization
Published in Journal of pharmaceutical and biomedical analysis (25-01-2011)“…The thermal properties of three matrix metalloproteinase (MMP) inhibitors were investigated using a variety of instrumental methods. Differential scanning…”
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Polymorphism of roxifiban
Published in Journal of pharmaceutical sciences (01-12-2002)“…Roxifiban was found to exist in two polymorphic forms. The polymorphs were detected by X-ray powder diffraction and solid-state carbon nuclear magnetic…”
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5
Utility of microcalorimetry in the characterization of the browning reaction
Published in Journal of pharmaceutical and biomedical analysis (01-06-1999)“…An isothermal microcalorimeter was utilized to characterize a model solid-state interaction. The degradation of the HIV protease inhibitor, DMP 450, in a…”
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Physicochemical properties of a nonpeptide cyclic urea HIV protease inhibitor (DMP 323)
Published in International journal of pharmaceutics (22-11-1996)“…DMP 323 ([4R-(4α, 5α, 6β, 7β)]-hexahydro-5,6-bis(hydroxy)-1,3-bis ([(4-hydroxymethyl)phenyl]methyl)-4,7-bis(phenylmethyl)-2H-1,3-diazepin-2-one), a potent…”
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Physicochemical properties of the novel heteropolyanion antiviral hexapotassium-α-vanado-11-tungstoborate (DuP 925)
Published in Pharmaceutical research (01-04-1992)“…Hexapotassium-alpha-vanado-11-tungstoborate (DuP 925) is a yellow irregular-shaped crystalline powder. The DSC thermogram indicates that decomposition begins…”
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