Search Results - "Vickers, Kasey"

Intercellular Transport of MicroRNAs by Boon, Reinier A, Vickers, Kasey C

“…Extracellular microRNAs (miRNA) are present in most biological fluids, relatively stable, and hold great potential for disease biomarkers and novel…”
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Lipid-based carriers of microRNAs and intercellular communication by Vickers, Kasey C., Remaley, Alan T.

“…Extracellular microRNAs (miRNAs) are uniquely stable in plasma, and the levels of specific circulating miRNAs can differ with disease. Extracellular miRNAs are…”
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Lipoprotein carriers of microRNAs by Michell, Danielle L., Vickers, Kasey C.

“…Lipoproteins, namely high-density lipoproteins (HDL), transport a wide-variety of cargo in addition to cholesterol and lipids. In 2011, HDL and low-density…”
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MicroRNAs are transported in plasma and delivered to recipient cells by high-density lipoproteins by Vickers, Kasey C, Shamburek, Robert D, Palmisano, Brian T, Remaley, Alan T, Shoucri, Bassem M

“…Circulating microRNAs (miRNA) are relatively stable in plasma and are a new class of disease biomarkers. Here we present evidence that high-density lipoprotein…”
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MicroRNAs in the onset and development of cardiovascular disease by Vickers, Kasey C, Rye, Kerry-Anne, Tabet, Fatiha

“…Physiological and pathological roles for small non-encoding miRNAs (microRNAs) in the cardiovascular system have recently emerged and are now widely studied…”
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HDL-small RNA Export, Transport, and Functional Delivery in Atherosclerosis by Vickers, Kasey C., Michell, Danielle L.

“…Purpose of Review This review highlights recent advances on the mechanisms and impact of HDL-small non-coding RNAs (sRNA) on intercellular communication in…”
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Transfer of Functional Cargo in Exomeres by Zhang, Qin, Higginbotham, James N., Jeppesen, Dennis K., Yang, Yu-Ping, Li, Wei, McKinley, Eliot T., Graves-Deal, Ramona, Ping, Jie, Britain, Colleen M., Dorsett, Kaitlyn A., Hartman, Celine L., Ford, David A., Allen, Ryan M., Vickers, Kasey C., Liu, Qi, Franklin, Jeffrey L., Bellis, Susan L., Coffey, Robert J.

“…Exomeres are a recently discovered type of extracellular nanoparticle with no known biological function. Herein, we describe a simple ultracentrifugation-based…”
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KRAS-dependent sorting of miRNA to exosomes by Cha, Diana J, Franklin, Jeffrey L, Dou, Yongchao, Liu, Qi, Higginbotham, James N, Demory Beckler, Michelle, Weaver, Alissa M, Vickers, Kasey, Prasad, Nirpesh, Levy, Shawn, Zhang, Bing, Coffey, Robert J, Patton, James G

“…Mutant KRAS colorectal cancer (CRC) cells release protein-laden exosomes that can alter the tumor microenvironment. To test whether exosomal RNAs also…”
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MicroRNA-223 coordinates cholesterol homeostasis by Vickers, Kasey C., Landstreet, Stuart R., Levin, Michael G., Shoucri, Bassem M., Toth, Cynthia L., Taylor, Robert C., Palmisano, Brian T., Tabet, Fatiha, Cui, Huanhuan L., Rye, Kerry-Anne, Sethupathy, Praveen, Remaley, Alan T.

“…Significance Results from this study represent a breakthrough in our understanding of posttranscriptional control of cholesterol metabolism and how microRNAs…”
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HDL-transferred microRNA-223 regulates ICAM-1 expression in endothelial cells by Tabet, Fatiha, Vickers, Kasey C., Cuesta Torres, Luisa F., Wiese, Carrie B., Shoucri, Bassem M., Lambert, Gilles, Catherinet, Claire, Prado-Lourenco, Leonel, Levin, Michael G., Thacker, Seth, Sethupathy, Praveen, Barter, Philip J., Remaley, Alan T., Rye, Kerry-Anne

“…High-density lipoproteins (HDL) have many biological functions, including reducing endothelial activation and adhesion molecule expression. We recently…”
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HDL and microRNA therapeutics in cardiovascular disease by Michell, Danielle L, Vickers, Kasey C

“…microRNAs (miRNA) are small non-coding RNAs (sRNA) that post-transcriptionally regulate gene (mRNA) expression and are implicated in many biological processes…”
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MicroRNA‐27b is a regulatory hub in lipid metabolism and is altered in dyslipidemia by Vickers, Kasey C., Shoucri, Bassem M., Levin, Michael G., Wu, Han, Pearson, Daniel S., Osei‐Hwedieh, David, Collins, Francis S., Remaley, Alan T., Sethupathy, Praveen

“…Cellular and plasma lipid levels are tightly controlled by complex gene regulatory mechanisms. Elevated plasma lipid content, or hyperlipidemia, is a…”
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Integrative roles of microRNAs in lipid metabolism and dyslipidemia by Sedgeman, Leslie R, Michell, Danielle L, Vickers, Kasey C

“…The purpose of the review is to discuss recent advances in microRNA (miRNA) regulation of lipid metabolism and highlight the importance of miRNA-mediated gene…”
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Antiinflammatory Effect of High-Density Lipoprotein Blunted by Delivery of Altered MicroRNA Cargo in Patients With Rheumatoid Arthritis by Wu, Qiong, Sheng, Quanhu, Michell, Danielle, Ramirez-Solano, Marisol, Posey, Olivia, Phothisane, Anastasiia, Shaik, Shahensha, Vickers, Kasey C, Ormseth, Michelle J

“…High-density lipoprotein (HDL) has well-characterized anti-atherogenic cholesterol efflux and antioxidant functions. Another function of HDL uncharacterized in…”
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Macrophage SR-BI modulates autophagy via VPS34 complex and PPARα transcription of Tfeb in atherosclerosis by Tao, Huan, Yancey, Patricia G, Blakemore, John L, Zhang, Youmin, Ding, Lei, Jerome, W Gray, Brown, Jonathan D, Vickers, Kasey C, Linton, MacRae F

“…Autophagy modulates lipid turnover, cell survival, inflammation, and atherogenesis. Scavenger receptor class B type I (SR-BI) plays a crucial role in lysosome…”
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Interrupted Glucagon Signaling Reveals Hepatic α Cell Axis and Role for L-Glutamine in α Cell Proliferation by Dean, E. Danielle, Li, Mingyu, Prasad, Nripesh, Wisniewski, Scott N., Von Deylen, Alison, Spaeth, Jason, Maddison, Lisette, Botros, Anthony, Sedgeman, Leslie R., Bozadjieva, Nadejda, Ilkayeva, Olga, Coldren, Anastasia, Poffenberger, Greg, Shostak, Alena, Semich, Michael C., Aamodt, Kristie I., Phillips, Neil, Yan, Hai, Bernal-Mizrachi, Ernesto, Corbin, Jackie D., Vickers, Kasey C., Levy, Shawn E., Dai, Chunhua, Newgard, Christopher, Gu, Wei, Stein, Roland, Chen, Wenbiao, Powers, Alvin C.

“…Decreasing glucagon action lowers the blood glucose and may be useful therapeutically for diabetes. However, interrupted glucagon signaling leads to α cell…”
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Anti‐Inflammatory Effect of High‐Density Lipoprotein Blunted by Delivery of Altered MicroRNA Cargo in Patients With Rheumatoid Arthritis by Wu, Qiong, Sheng, Quanhu, Michell, Danielle, Ramirez‐Solano, Marisol, Posey, Olivia, Phothisane, Anastasiia, Shaik, Shahensha, Vickers, Kasey C., Ormseth, Michelle J.

“…Objective High‐density lipoprotein (HDL) has well‐characterized anti‐atherogenic cholesterol efflux and antioxidant functions. Another function of HDL…”
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MicroRNA-29 Fine-tunes the Expression of Key FOXA2-Activated Lipid Metabolism Genes and Is Dysregulated in Animal Models of Insulin Resistance and Diabetes by KURTZ, C. Lisa, PECK, Bailey C. E, BIDDINGER, Sudha B, VICKERS, Kasey C, SETHUPATHY, Praveen, FANNIN, Emily E, BEYSEN, Carine, JI MIAO, LANDSTREET, Stuart R, SHENGLI DING, TURAGA, Vandana, LUND, P. Kay, TURNER, Scott

“…MicroRNAs (miRNAs) have emerged as biomarkers of metabolic status, etiological factors in complex disease, and promising drug targets. Recent reports suggest…”
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Apolipoprotein A‐I in mouse cerebrospinal fluid derives from the liver and intestine via plasma high‐density lipoproteins assembled by ABCA1 and LCAT by Tsujita, Maki, Vaisman, Boris, Chengyu, Liu, Vickers, Kasey C., Okuhira, Kei‐ichiro, Braesch‐Andersen, Sten, Remaley, Alan T.

“…Apolipoprotein (apo) A‐I, the major structural protein of high‐density lipoprotein (HDL), is present in human and mouse cerebrospinal fluid (CSF) despite its…”
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LDL delivery of microbial small RNAs drives atherosclerosis through macrophage TLR8 by Allen, Ryan M., Michell, Danielle L., Cavnar, Ashley B., Zhu, Wanying, Makhijani, Neil, Contreras, Danielle M., Raby, Chase A., Semler, Elizabeth M., DeJulius, Carlisle, Castleberry, Mark, Zhang, Youmin, Ramirez-Solano, Marisol, Zhao, Shilin, Duvall, Craig, Doran, Amanda C., Sheng, Quanhu, Linton, MacRae F., Vickers, Kasey C.

“…Macrophages present a spectrum of phenotypes that mediate both the pathogenesis and resolution of atherosclerotic lesions. Inflammatory macrophage phenotypes…”
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