Search Results - "Vickaryous, Nicola K."
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Dynamic reprogramming of DNA methylation at an epigenetically sensitive allele in mice
Published in PLoS genetics (01-04-2006)“…There is increasing evidence in both plants and animals that epigenetic marks are not always cleared between generations. Incomplete erasure at genes…”
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An N-Ethyl-N-Nitrosourea Screen for Genes Involved in Variegation in the Mouse
Published in Proceedings of the National Academy of Sciences - PNAS (24-05-2005)“…We have developed a sensitized screen to identify genes involved in gene silencing, using random N-ethyl-N-nitrosourea mutagenesis on mice carrying a…”
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Apc mice: Models, modifiers and mutants
Published in Pathology, research and practice (01-01-2008)“…The mouse provides an excellent in vivo system with which to model human diseases and to test therapies. Mutations in the Adenomatous polyposis coli (APC) gene…”
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A genome-wide screen for modifiers of transgene variegation identifies genes with critical roles in development
Published in Genome biology (19-12-2008)“…Some years ago we established an N-ethyl-N-nitrosourea screen for modifiers of transgene variegation in the mouse and a preliminary description of the first…”
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Deletion of N-terminal amino acids from human lecithin:cholesterol acyltransferase differentially affects enzyme activity toward α- and β-substrate lipoproteins
Published in Biochimica et biophysica acta (21-03-2003)“…Lecithin:cholesterol acyltransferase (LCAT) is the enzyme responsible for generation of the majority of the cholesteryl esters (CE) in human plasma. Although…”
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6
An N-ethyl-Nnitrosourea screen for genes involved in variegation in the mouse
Published in Proceedings of the National Academy of Sciences - PNAS (24-05-2005)“…We have developed a sensitized screen to identify genes involved in gene silencing, using random N-ethyl-N-nitrosourea mutagenesis on mice carrying a…”
Get full text
Journal Article