Search Results - "Vick, Andrew"

Engineering and characterization of the long-acting glucagon-like peptide-1 analogue LY2189265, an Fc fusion protein by Glaesner, Wolfgang, Mark Vick, Andrew, Millican, Rohn, Ellis, Bernice, Tschang, Sheng-Hung, Tian, Yu, Bokvist, Krister, Brenner, Martin, Koester, Anja, Porksen, Niels, Etgen, Garret, Bumol, Tom

“…Background Glucagon‐like peptide‐1 (GLP‐1) receptor agonists are novel agents for type 2 diabetes treatment, offering glucose‐dependent insulinotropic effects,…”
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Non-destructive imaging of buried electronic interfaces using a decelerated scanning electron beam by Hirohata, Atsufumi, Yamamoto, Yasuaki, Murphy, Benedict A., Vick, Andrew J.

“…Recent progress in nanotechnology enables the production of atomically abrupt interfaces in multilayered junctions, allowing for an increase in the number of…”
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Characterization of All Graphs with a Failed Skew Zero Forcing Number of 1 by Johnson, Aidan, Vick, Andrew E., Narayan, Darren A.

“…Given a graph G, the zero forcing number of G, Z(G), is the minimum cardinality of any set S of vertices of which repeated applications of the forcing rule…”
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Highly Efficient Spin-Current Operation in a Cu Nano-Ring by Murphy, Benedict A., Vick, Andrew J., Samiepour, Marjan, Hirohata, Atsufumi

“…An all-metal lateral spin-valve structure has been fabricated with a medial Copper nano-ring to split the diffusive spin-current path. We have demonstrated…”
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Increased bioavailability of celecoxib under fed versus fasted conditions is determined by postprandial bile secretion as demonstrated in a dynamic gastrointestinal model by Lyng, Eric, Havenaar, Robert, Shastri, Prathap, Hetsco, Lucy, Vick, Andrew, Sagartz, John

“…The objective of this study was to utilize physiologically relevant dynamic dissolution testing with the TNO intestinal model (TIM-1) in vitro gastrointestinal…”
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Pharmacokinetics, Pharmacodynamics, Safety, and Tolerability of Nebulized Sodium Nitrite (AIR001) Following Repeat-Dose Inhalation in Healthy Subjects by Rix, Peter J., Vick, Andrew, Attkins, Neil J., Barker, Geoffrey E., Bott, Adrian W., Alcorn, Harry, Gladwin, Mark T., Shiva, Sruti, Bradley, Stephen, Hussaini, Azra, Hoye, William L., Parsley, Ed L., Masamune, Hiroko

“…Introduction The efficacy of nebulized sodium nitrite (AIR001) has been demonstrated in animal models of pulmonary arterial hypertension (PAH), but it was not…”
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Growth and Characterisation of Antiferromagnetic Ni2MnAl Heusler Alloy Films by Huminiuc, Teodor, Whear, Oliver, Vick, Andrew J., Lloyd, David C., Vallejo-Fernandez, Gonzalo, O’Grady, Kevin, Hirohata, Atsufumi

“…Recent rapid advancement in antiferromagnetic spintronics paves a new path for efficient computing with THz operation. To date, major studies have been…”
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Clinically indicated replacement versus routine replacement of peripheral venous catheters by Vick, Andrew M

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Clinically indicated replacement versus routine replacement of peripheral venous catheters: Summaries of Nursing Care-Related Systematic Reviews from the Cochrane Library by Vick, Andrew M

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Predictive Dose-Based Estimation of Systemic Exposure Multiples in Mouse and Monkey Relative to Human for Antisense Oligonucleotides With 2′-O-(2-Methoxyethyl) Modifications by Yu, Rosie Z, Grundy, John S, Henry, Scott P, Kim, Tae-Won, Norris, Daniel A, Burkey, Jennifer, Wang, Yanfeng, Vick, Andrew, Geary, Richard S

“…Evaluation of species differences and systemic exposure multiples (or ratios) in toxicological animal species versus human is an ongoing exercise during the…”
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Accelerated pharmacokinetics and glucodynamics of prandial insulins injected with recombinant human hyaluronidase by Vaughn, Daniel E, Yocum, Richard C, Muchmore, Douglas B, Sugarman, Barry J, Vick, Andrew M, Bilinsky, Igor P, Frost, Gregory I

“…This phase 1 study investigated the pharmacokinetics (PK) and glucodynamics of insulin lispro (Humalog; Eli Lilly and Co., Indianapolis, IN) or regular human…”
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pI-shifted insulin analogs with extended in vivo time action and favorable receptor selectivity by KOHN, Wayne D, MICANOUIC, Radmila, MAYER, John P, DIMARCHI, Richard D, MYERS, Sharon L, VICK, Andrew M, KAHL, Steuen D, LIANSHAN ZHANG, STRIFLER, Beth A, SHUN LI, JING SHANG, BEALS, John M

“…A long-acting (basal) insulin capable of delivering flat, sustained, reproducible glycemic control with once daily administration represents an improvement in…”
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Pharmacokinetics and hepatic extraction of recombinant human parathyroid hormone, hPTH (1-34), in rat, dog, and monkey by Jones, Karen O, Owusu-Ababio, Godfried, Vick, Andrew M, Khan, M Amin

“…The pharmacokinetics (PK) and hepatic extraction (E(H)) of human PTH (1-34), hPTH (1-34), were characterized in rat, dog, and monkey, following intraportal…”
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Methyltestosterone pharmacolinetics and oral bioavailability in rainbow trout ( Oncorhynchus mykiss) by Vick, Andrew M, Hayton, William L

“…14C-methyltestosterone pharmacokinetics after intraarterial (2 and 20 mg/kg) and oral (30 mg/kg) administration were investigated in rainbow trout at 15°C…”
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The effect of psyllium consumption on weight, body mass index, lipid profile, and glucose metabolism in diabetic patients: A systematic review and dose‐response meta‐analysis of randomized controlled trials by Xiao, Zhifang, Chen, Hui, Zhang, Yu, Deng, Hui, Wang, KunWei, Bhagavathula, Akshaya Srikanth, Almuhairi, Shamma Jauaan, Ryan, Paul M., Rahmani, Jamal, Dang, Minyan, Kontogiannis, Vasileios, Vick, Andrew, Wei, Yuhe

“…Water‐soluble dietary fibers have been shown to improve lipid profile and glucose metabolism in diabetes. The aim of this study was to review the effects of…”
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AMG 416 (velcalcetide) is a novel peptide for the treatment of secondary hyperparathyroidism in a single-dose study in hemodialysis patients by Martin, Kevin J, Pickthorn, Karen, Huang, Saling, Block, Geoffrey A, Vick, Andrew, Mount, Peter F, Power, David A, Bell, Gregory

“…AMG 416 (velcalcetide), a novel peptide agonist of the calcium-sensing receptor, lowers plasma parathyroid hormone in preclinical uremic animal models and in…”
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Biological Matrix Supply Chain Shortages: More Matrices Are Now Rare—the Case for Surrogate Matrices by Dubiel, Evan A., Myler, Heather, Arnold, Mark E., Bennett, Patrick, Gatz, Jeff, Groeber, Elizabeth, Gupta, Seema, Kane, Cheikh, Li, Fumin, Mylott, William, Noah, Courtney, O’Dell, Mark, Tewalt, Eric, Warrino, Dominic, Vick, Andrew

“…The COVID-19 pandemic has strained the biological matrix supply chain. An upsurge in demand driven by numerous COVID-19 therapeutic and vaccine development…”
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Implementation of dose superimposition to introduce multiple doses for a mathematical absorption model (transit compartment model) by Shen, Jun, Boeckmann, Alison, Vick, Andrew

“…A mathematical absorption model (e.g. transit compartment model) is useful to describe complex absorption process. However, in such a model, an assumption has…”
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Velcalcetide (AMG 416), a novel peptide agonist of the calcium-sensing receptor, reduces serum parathyroid hormone and FGF23 levels in healthy male subjects by Martin, Kevin J, Bell, Gregory, Pickthorn, Karen, Huang, Saling, Vick, Andrew, Hodsman, Peter, Peacock, Munro

“…Velcalcetide, also known as AMG 416, is a novel, long-acting selective peptide agonist of the calcium sensing receptor. It is being developed as an intravenous…”
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A pharmacokinetic/pharmacodynamic model for AMG 416, a novel calcimimetic peptide, following a single intravenous dose in healthy subjects by Shen, Jun, Xiao, Jim, Pickthorn, Karen, Huang, Saling, Bell, Gregory, Vick, Andrew, Chen, Ping

“…AMG 416 is a novel peptide agonist of the calcium‐sensing receptor. In support of the clinical development program, a pharmacokinetic (PK)/pharmacodynamic (PD)…”
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