Search Results - "Vicic, David A"

Direct Difluoromethylation of Aryl Halides via Base Metal Catalysis at Room Temperature by Xu, Long, Vicic, David A

“…A stable and isolable difluoro­methyl zinc reagent has been prepared through the reaction of ICF2H with diethyl zinc and DMPU. This new zinc reagent is a…”
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Nickel-Catalyzed Synthesis of Aryl Trifluoromethyl Sulfides at Room Temperature by Zhang, Cheng-Pan, Vicic, David A

“…Inexpensive nickel–bipyridine complexes were found to be active for the trifluoromethylthiolation of aryl iodides and aryl bromides at room temperature using…”
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Oxidative Trifluoromethylthiolations of Aryl Boronic Acids Using a Copper/O2-Based Protocol by Zhang, Cheng-Pan, Vicic, David A.

“…All you need is air: A new protocol has been developed which can mediate the coupling of aryl and vinyl boronic acids at room temperature in high yields (see…”
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Manganese-Catalyzed Aerobic Oxytrifluoromethylation of Styrene Derivatives Using CF3SO2Na as the Trifluoromethyl Source by Yang, Yi, Liu, Yingle, Jiang, Yan, Zhang, Yu, Vicic, David A

“…A mild and practical protocol for manganese-catalyzed aerobic oxytrifluoromethylation of olefinic bonds of styrene derivatives using CF3SO2Na (Langlois’…”
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Active Trifluoromethylating Agents from Well-Defined Copper(I)−CF3 Complexes by Dubinina, Galyna G, Furutachi, Hideki, Vicic, David A

“…The first examples of isolable and structurally characterized Cu(I)−CF3 complexes are reported. N-Heterocyclic carbene (NHC)-supported copper tert-butoxide…”
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Triphenylphosphine-Mediated Deoxygenative Reduction of CF3SO2Na and Its Application for Trifluoromethylthiolation of Aryl Iodides by Yang, Yi, Xu, Long, Yu, Siqi, Liu, Xiaoqiang, Zhang, Yu, Vicic, David A.

“…We report herein a practical method for taming Langlois’ reagent CF3SO2Na to generate CuSCF3 by a triphenylphospine‐mediated deoxygenative reduction process…”
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Unliganded HIV-1 gp120 core structures assume the CD4-bound conformation with regulation by quaternary interactions and variable loops by Kwon, Young Do, Finzi, Andrés, Wu, Xueling, Dogo-Isonagie, Cajetan, Lee, Lawrence K, Moore, Lucas R, Schmidt, Stephen D, Stuckey, Jonathan, Yang, Yongping, Zhou, Tongqing, Zhu, Jiang, Vicic, David A, Debnath, Asim K, Shapiro, Lawrence, Bewley, Carole A, Mascola, John R, Sodroski, Joseph G, Kwong, Peter D

“…The HIV-1 envelope (Env) spike (gp1203/gp413) undergoes considerable structural rearrangements to mediate virus entry into cells and to evade the host immune…”
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Exploiting the trifluoroethyl group as a precatalyst ligand in nickel-catalyzed Suzuki-type alkylations by Yang, Yi, Zhou, Qinghai, Cai, Junjie, Xue, Teng, Liu, Yingle, Jiang, Yan, Su, Yumei, Chung, Lungwa, Vicic, David A

“…We report herein the exploitment of the partially fluorinated trifluoroethyl as precatalyst ligands in nickel-catalyzed Suzuki-type alkylation and…”
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An Organocatalytic Asymmetric Nazarov Cyclization by Basak, Ashok K, Shimada, Naoyuki, Bow, William F, Vicic, David A, Tius, Marcus A

“…An organocatalytic asymmetric Nazarov cyclization of diketoesters that proceeds by means of a dual activation mechanism has been developed. Screening of a…”
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Ligand Redox Effects in the Synthesis, Electronic Structure, and Reactivity of an Alkyl−Alkyl Cross-Coupling Catalyst by Jones, Gavin D, Martin, Jason L, McFarland, Chris, Allen, Olivia R, Hall, Ryan E, Haley, Aireal D, Brandon, R. Jacob, Konovalova, Tatyana, Desrochers, Patrick J, Pulay, Peter, Vicic, David A

“…The ability of the terpyridine ligand to stabilize alkyl complexes of nickel has been central in obtaining a fundamental understanding of the key processes…”
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Versatile Route to Arylated Fluoroalkyl Bromide Building Blocks by Kaplan, Peter T, Vicic, David A

“…New difunctionalized and fluoroalkylated silyl reagents have been prepared that react with silver and copper salts to afford active catalysts that can be used…”
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Exploring Mechanisms in Ni Terpyridine Catalyzed C–C Cross-Coupling Reactions—A Review by Budnikova, Yulia, Vicic, David, Klein, Axel

“…In recent years, nickel has entered the stage for catalyzed C-C cross-coupling reactions, replacing expensive palladium, and in some cases enabling the use of…”
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Synthetic utility of dizinc reagents derived from 1,4-diiodo- and 1,4-dibromooctafluorobutane by Kaplan, Peter T., Chen, Bo, Vicic, David A.

“…A modified procedure to prepare [(MeCN)2Zn((CF2)4)2Zn(MeCN)2] has been developed that allows for more reproducible yields of novel organofluorines during…”
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Exploring Trifluoromethylation Reactions at Nickel: A Structural and Reactivity Study by Dubinina, Galyna G, Brennessel, William W, Miller, Jennifer L, Vicic, David A

“…A variety of nickel(aryl)(CF3) complexes supported by a chelating bisphosphine were successfully prepared in order to investigate the possibility of reductive…”
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Stepwise Conversion of a Platinum Dimethyl Complex to a Perfluorometallacyclobutane Derivative by Xu, Long, Solowey, Douglas P, Vicic, David A

“…In this report, we have demonstrated proof-in-principle that simple dimethyl metal complexes could be used to generate perfluorometallacyclobutane derivatives…”
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Decarboxylative trifluoromethylation of aryl halides using well-defined copper–trifluoroacetate and –chlorodifluoroacetate precursors by McReynolds, Kristen A., Lewis, Robert S., Ackerman, Laura K.G., Dubinina, Galyna G., Brennessel, William W., Vicic, David A.

“…New synthetic routes to (NHC)copper–trifluoroacetate and –chlorodifluoroacetate complexes were developed (NHC = N-heterocyclic carbenes) so baseline reactivity…”
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Electronic Structure of Four-Coordinate C3v Nickel(II) Scorpionate Complexes:  Investigation by High-Frequency and -Field Electron Paramagnetic Resonance and Electronic Absorption Spectroscopies by DESROCHERS, Patrick J., TELSER, Joshua, ZVYAGIN, S. A., OZAROWSKI, Andrew, KRZYSTEK, J., VICIC, David A.

“…A series of complexes of formula TpNiX, where Tp*- = hydrotris(3,5-dimethylpyrazole)borate and X = Cl, Br, I, has been characterized by electronic absorption…”
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Magnitudes of Electron-Withdrawing Effects of the Trifluoromethyl Ligand in Organometallic Complexes of Copper and Nickel by Kieltsch, Iris, Dubinina, Galyna G, Hamacher, Claudia, Kaiser, André, Torres-Nieto, Jorge, Hutchison, John M, Klein, Axel, Budnikova, Yulia, Vicic, David A

“…A variety of nickel and copper complexes bearing the trifluoromethyl ligand have been prepared in order to quantify by electrochemical methods the redox…”
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Organocatalytic asymmetric aza-Nazarov cyclization of an azirine by Shimada, Naoyuki, Ashburn, Bradley O, Basak, Ashok K, Bow, William F, Vicic, David A, Tius, Marcus A

“…An unusual organocatalytic asymmetric cyclization of a ketoazirine that is accompanied by a kinetic resolution leads to…”
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Comparative profiling of well-defined copper reagents and precursors for the trifluoromethylation of aryl iodides by Kaplan, Peter T, Lloyd, Jessica A, Chin, Mason T, Vicic, David A

“…A number of copper reagents were compared for their effectiveness in trifluoromethylating 4-iodobiphenyl, 4-iodotoluene, and 2-iodotoluene. Yields over time…”
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