Search Results - "Vicente Tavares, Angela Maria"

Neonatal nonviral gene editing with the CRISPR/Cas9 system improves some cardiovascular, respiratory, and bone disease features of the mucopolysaccharidosis I phenotype in mice by Schuh, Roselena Silvestri, Gonzalez, Esteban Alberto, Tavares, Angela Maria Vicente, Seolin, Bruna Gazzi, Elias, Lais de Souza, Vera, Luisa Natalia Pimentel, Kubaski, Francyne, Poletto, Edina, Giugliani, Roberto, Teixeira, Helder Ferreira, Matte, Ursula, Baldo, Guilherme

“…Mucopolysaccharidosis type I (MPS I) is caused by deficiency of alpha-L-iduronidase (IDUA), leading to multisystemic accumulation of glycosaminoglycans (GAG)…”
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Cathepsin B inhibition attenuates cardiovascular pathology in mucopolysaccharidosis I mice by Gonzalez, Esteban Alberto, Martins, Giselle Renata, Tavares, Angela Maria Vicente, Viegas, Michelle, Poletto, Edina, Giugliani, Roberto, Matte, Ursula, Baldo, Guilherme

“…Mucopolysaccharidosis type I (MPS I) is a lysosomal storage disorder with multisystemic features, including heart enlargement, heart valve dysfunction, and…”
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Chronic whole-body heat treatment relieves atherosclerotic lesions, cardiovascular and metabolic abnormalities, and enhances survival time restoring the anti-inflammatory and anti-senescent heat shock response in mice by Bruxel, Maciel Alencar, Tavares, Angela Maria Vicente, Zavarize Neto, Luiz Domingues, de Souza Borges, Victor, Schroeder, Helena Trevisan, Bock, Patricia Martins, Rodrigues, Maria Inês Lavina, Belló-Klein, Adriane, Homem de Bittencourt, Paulo Ivo

“…Unhealthy lifestyle persistently feeds forward inflammation in metabolic organs thus imposing senescence-associated secretory phenotype (SASP), as observed in…”
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Losartan improves aortic dilatation and cardiovascular disease in mucopolysaccharidosis I by Gonzalez, Esteban Alberto, Tavares, Angela Maria Vicente, Poletto, Edina, Giugliani, Roberto, Matte, Ursula, Baldo, Guilherme

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Effects of enzyme replacement therapy started late in a murine model of mucopolysaccharidosis type I by Pasqualim, Gabriela, Baldo, Guilherme, de Carvalho, Talita Giacomet, Tavares, Angela Maria Vicente, Giugliani, Roberto, Matte, Ursula

“…Mucopolysaccharidosis type I (MPS I) is a progressive disorder caused by deficiency of α-L-iduronidase (IDUA), which leads to storage of heparan and dermatan…”
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Effects of diaphragmatic contraction on lower limb venous return and central hemodynamic parameters contrasting healthy subjects versus heart failure patients at rest and during exercise by Balzan, Fernanda Machado, Silva, Régis Chiarelli, Silva, Danton Pereira, Sanches, Paulo Roberto Stefani, Tavares, Angela Maria Vicente, Ribeiro, Jorge Pinto, Berton, Danilo Cortozi, Clausell, Nadine Oliveira

“…The main objective was to assess the effects of abdominal breathing (AB) versus subject's own breathing on femoral venous blood flow (Qfv) and their…”
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Redox-sensitive prosurvival and proapoptotic protein expression in the myocardial remodeling post-infarction in rats by Schenkel, Paulo Cavalheiro, Tavares, Angela Maria Vicente, Fernandes, Rafael Oliveira, Diniz, Gabriela Placoná, Bertagnolli, Mariane, da Rosa Araujo, Alex Sander, Barreto-Chaves, Maria Luiza, Ribeiro, Maria Flavia Marques, Clausell, Nadine, Belló-Klein, Adriane

“…In this study, we investigated the oxidative stress influence in some prosurvival and proapoptotic proteins after myocardial infarction (MI). Male Wistar rats…”
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In vivo genome editing of mucopolysaccharidosis I mice using the CRISPR/Cas9 system by Schuh, Roselena Silvestri, Poletto, Édina, Pasqualim, Gabriela, Tavares, Angela Maria Vicente, Meyer, Fabíola Shons, Gonzalez, Esteban Alberto, Giugliani, Roberto, Matte, Ursula, Teixeira, Helder Ferreira, Baldo, Guilherme

“…Mucopolysaccharidosis type I (MPS I) is a multisystemic disorder caused by the deficiency of alpha-L-iduronidase (IDUA) that leads to intracellular…”
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Characterization of heart disease in mucopolysaccharidosis type II mice by Tavares, Angela Maria Vicente, Gonzalez, Esteban Alberto, Viana, Isabelle Souza, Visioli, Fernanda, Vera, Luisa Natalia Pimentel, Baldo, Guilherme

“…•Mucopolysaccharidosis type II leads to progressive loss of cardiac function.•Iduronate-2-sulfatase enzyme deficiency causes damage to the cardiovascular…”
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Effects of Copaiba Oil in Peripheral Markers of Oxidative Stress in a Model of Cor Pulmonale in Rats by Campos, Cristina, Turck, Patrick, Tavares, Angela Maria Vicente, Corssac, Giana, Lacerda, Denise, Araujo, Alex, Llesuy, Susana, Klein, Adriane Bello

“…To date, copaiba oil's systemic effects have never documented in Cor pulmonale induced by monocrotaline. To investigate copaiba oil's effects in peripheral…”
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Cardiac pathology in mucopolysaccharidosis I mice: Losartan modifies ERK1/2 activation during cardiac remodeling by Gonzalez, Esteban Alberto, Tobar Leitão, Santiago Alonso, Soares, Douglas dos Santos, Tavares, Angela Maria Vicente, Giugliani, Roberto, Baldo, Guilherme, Matte, Ursula

“…Mucopolysaccharidosis type I (MPS I) is a lysosomal storage disorder caused by mutations in the IDUA gene, that codifies the alpha‐L‐iduronidase enzyme, which…”
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Progressive heart disease in mucopolysaccharidosis type I mice may be mediated by increased cathepsin B activity by Baldo, Guilherme, Tavares, Angela Maria Vicente, Gonzalez, Esteban, Poletto, Edina, Mayer, Fabiana Quoos, da Silveira Matte, Ursula, Giugliani, Roberto

“…Abstract Mucopolysaccharidosis type I (MPS I) is a lysosomal disorder characterized by a deficiency of alpha-L-iduronidase and storage of undegraded…”
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Copaiba Oil Attenuates Right Ventricular Remodeling by Decreasing Myocardial Apoptotic Signaling in Monocrotaline-Induced Rats by Campos-Carraro, Cristina, Turck, Patrick, de Lima-Seolin, Bruna Gazzi, Tavares, Angela Maria Vicente, dos Santos Lacerda, Denise, Corssac, Giana Blume, Teixeira, Rayane Brinck, Hickmann, Alexandre, Llesuy, Susana, da Rosa Araujo, Alex Sander, Belló-Klein, Adriane

“…There is an increase in oxidative stress and apoptosis signaling during the transition from hypertrophy to right ventricular (RV) failure caused by pulmonary…”
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Aerobic Exercise Promotes a Decrease in Right Ventricle Apoptotic Proteins in Experimental Cor Pulmonale by Colombo, Rafael, Siqueira, Rafaela, Conzatti, Adriana, Fernandes, Tânia Regina Gattelli, Tavares, Angela Maria Vicente, Araújo, Alex Sander da Rosa, Belló-Klein, Adriane

“…Pulmonary arterial hypertension is characterized by progressive increases in resistance and pressure in the pulmonary artery and Cor pulmonale. The effect of…”
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Effect of free and nanoencapsulated copaiba oil on monocrotaline-induced pulmonary arterial hypertension by Campos, Cristina, Luz de Castro, Alexandre, Vicente Tavares, Angela Maria, Fernandes, Rafael Oliveira, Ortiz, Vanessa Duarte, Barboza, Tatiane Evelyn, Pereira, Cláudio, Apel, Miriam, Santos da Silva, Onilda, Llesuy, Susana, Sander da Rosa Araujo, Alex, Belló-Klein, Adriane

“…ABSTRACTCopaiba oil comes from an Amazonian tree and has been used as an alternative medicine in Brazil. However, it has not been investigated yet in the…”
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Bone marrow derived cells decrease inflammation but not oxidative stress in an experimental model of acute myocardial infarction by Tavares, Angela Maria Vicente, da Rosa Araújo, Alex Sander, Baldo, Guilherme, Matte, Ursula, Khaper, Neelam, Belló-Klein, Adriane, Rohde, Luis Eduardo, Clausell, Nadine

“…Bone marrow cell (BMC) therapy is thought to exert beneficial effects on the infarcted heart. We assessed cardiac function and its correlation with redox…”
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Atorvastatin administered before myocardial infarction in rats improves contractility irrespective of metabolic changes by Lehnen, Tatiana Ederich, Lehnen, Alexandre Machado, Tavares, Angela Maria Vicente, Belló-Klein, Adriane, Markoski, Melissa Medeiros, Machado, Ubiratan Fabres, Schaan, Beatriz

“…Summary Statins have a beneficial effect after myocardial infarction, but the relationship between glucose transporters and their use before the event has not…”
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Deleterious effects of interruption followed by reintroduction of enzyme replacement therapy on a lysosomal storage disorder by Schneider, A, Matte, U, Pasqualim, G, Tavares, A, Mayer, F, Martinelli, B, Ribas, G.S, Vargas, C.R, Giugliani, R, Baldo, G

“…Abstract Temporary interruption of enzyme replacement therapy (ERT) in patients with different lysosomal storage disorders (LSD) may happen for different…”
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Intraperitoneal implant of recombinant encapsulated cells overexpressing alpha- l -iduronidase partially corrects visceral pathology in mucopolysaccharidosis type I mice by Baldo, Guilherme, Mayer, Fabiana Quoos, Martinelli, Barbara, Meyer, Fabiola Schons, Burin, Maira, Meurer, Luise, Tavares, Angela Maria Vicente, Giugliani, Roberto, Matte, Ursula

“…Abstract Background aims Mucopolysaccharidosis type I (MPS I) is characterized by deficiency of the enzyme alpha- l -iduronidase (IDUA) and storage of…”
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Time course of hydrogen peroxide–thioredoxin balance and its influence on the intracellular signalling in myocardial infarction by Schenkel, Paulo Cavalheiro, Tavares, Angela Maria Vicente, Fernandes, Rafael Oliveira, Diniz, Gabriela Placoná, Ludke, Ana Raquel Lehenbauer, Ribeiro, Maria Flavia Marques, da Rosa Araujo, Alex Sander, Barreto‐Chaves, Maria Luiza, Belló‐Klein, Adriane

“…We investigated the myocardial thioredoxin‐1 and hydrogen peroxide concentrations and their association with some prosurvival and pro‐apoptotic proteins,…”
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