Search Results - "Vicente‐Gutiérrez, Carlos"

Mitochondrial sodium/calcium exchanger NCLX regulates glycolysis in astrocytes, impacting on cognitive performance by Cabral‐Costa, João Victor, Vicente‐Gutiérrez, Carlos, Agulla, Jesús, Lapresa, Rebeca, Elrod, John W., Almeida, Ángeles, Bolaños, Juan P., Kowaltowski, Alicia J.

“…Intracellular Ca2+ concentrations are strictly controlled by plasma membrane transporters, the endoplasmic reticulum, and mitochondria, in which Ca2+ uptake is…”
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Opa1 relies on cristae preservation and ATP synthase to curtail reactive oxygen species accumulation in mitochondria by Quintana-Cabrera, Rubén, Manjarrés-Raza, Israel, Vicente-Gutiérrez, Carlos, Corrado, Mauro, Bolaños, Juan P., Scorrano, Luca

“…Reactive oxygen species (ROS) are a common product of active mitochondrial respiration carried in mitochondrial cristae, but whether cristae shape influences…”
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Intertwined ROS and Metabolic Signaling at the Neuron-Astrocyte Interface by Vicente-Gutiérrez, Carlos, Jiménez-Blasco, Daniel, Quintana-Cabrera, Rubén

“…Metabolism and redox signalling share critical nodes in the nervous system. In the last years, a series of major findings have challenged the current vision on…”
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MiRNA expression profile of chronic lymphocytic leukemia patients with 13q deletion by Hernández-Sánchez, María, Rodríguez, Ana E, Hernández, José-Ángel, Lumbreras, Eva, Sarasquete, María-Eugenia, Martín, Ana-África, Benito, Rocío, Vicente-Gutiérrez, Carlos, Robledo, Cristina, Heras, Natalia de las, Rodríguez, Juan-Nicolás, Alcoceba, Miguel, Coca, Alfonso García de, Aguilar, Carlos, González, Marcos, Hernández-Rivas, Jesús-María

“…Highlights • A distinct miRNA signature in 13q- CLL patients depending on the % of cells with this alteration. • Deregulation of miR-143 and miR-155 could…”
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Control of bioenergetics and ROS levels by mitochondrial cristae by Quintana-Cabrera, Rubén, Manjarrés-Raza, Israel, Vicente-Gutiérrez, Carlos, Corrado, Mauro, Bolaños, Juan Pedro, Scorrano, Luca

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Abrogating mitochondrial ROS in neurons or astrocytes reveals cell-specific impact on mouse behaviour by Vicente-Gutierrez, Carlos, Bonora, Nicolo, Jimenez-Blasco, Daniel, Lopez-Fabuel, Irene, Bates, Georgina, Murphy, Michael P., Almeida, Angeles, Bolaños, Juan P.

“…Cells naturally produce mitochondrial reactive oxygen species (mROS), but the in vivo pathophysiological significance has long remained controversial. Within…”
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An ex vivo Approach to Assess Mitochondrial ROS by Flow Cytometry in AAV-tagged Astrocytes in Adult Mice by Vicente-Gutierrez, Carlos, Bolaños, Juan P

“…Mitochondrial reactive oxygen species (mROS) are naturally produced signalling molecules extremely relevant for understanding both health- and…”
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Mitochondrial cristae shape regulates ROS production under restrictive glycolysis by Quintana-Cabrera, Rubén, Manjarrés-Raza, Israel, Vicente-Gutiérrez, Carlos, Corrado, Mauro, Bolaños, Juan Pedro, Scorrano, Luca

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Abrogating mitochondrial ROS in neurons or astrocytes reveals cell-specific impact on mouse behaviour by Vicente-Gutiérrez, Carlos, Bonora, Nicoló, Jiménez-Blasco, Daniel, Fabuel, Irene López, Bates, Georgina, Murphy, Mike, Almeida, Ángeles, Bolaños, Juan P.

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Transcriptomic and metabolic signatures of neural cells cultured under a physiologic-like environment by Fernandez, Emilio, Warde, Moussa, Manjarres-Raza, Israel, Bobo-Jimenez, Veronica, Martinez-Luna, Maria, Vicente-Gutierrez, Carlos, Garcia-Rodriguez, Dario, Jimenez-Blasco, Daniel, Almeida, Angeles, Bolaños, Juan P.

“…Cultured brain cells are used conventionally to investigate fundamental neurobiology and identify therapeutic targets against neural diseases. However,…”
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Astrocytic mitochondrial ROS modulate brain metabolism and mouse behaviour by Vicente-Gutierrez, Carlos, Bonora, Nicoló, Bobo-Jimenez, Veronica, Jimenez-Blasco, Daniel, Lopez-Fabuel, Irene, Fernandez, Emilio, Josephine, Charlene, Bonvento, Gilles, Enriquez, Jose A., Almeida, Angeles, Bolaños, Juan P.

“…To satisfy its high energetic demand 1 , the brain depends on the metabolic cooperation of various cell types 2 – 4 . For example, astrocytic-derived lactate…”
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Aberrant PFKFB3-induced glycolysis in neurons in vivo causes mouse behavioral impairment by mitochondrial redox stress by Jimenez-Blasco, Daniel, García-Macia, Marina, Vicente-Gutierrez, Carlos, Quintana-Cabrera, Ruben, Fernandez, Emilio, Carmeliet, Peter, Almeida, Angeles, Bolaños, Juan P.

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L-41 - Brain redox bioenergetics are determined by OXPHOS organization in neurons and astrocytes by Bolaños, Juan Pedro, Jiménez-Blasco, Daniel, Lopez-Fabuel, Irene, Vicente-Gutierrez, Carlos, Bonora, Nicolo, Almeida, Angeles

“…Energy and redox conservation in the brain requires a tight and complementary metabolic cooperation between distinct cell types. Neurons are highly dependent…”
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Brain redox bioenergetics are determined by OXPHOS organization in neurons and astrocytes by Bolaños, Juan Pedro, Jiménez-Blasco, Daniel, Lopez-Fabuel, Irene, Vicente-Gutierrez, Carlos, Bonora, Nicolo, Almeida, Angeles

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Mitochondrial ROS contribute to neuronal ceroid lipofuscinosis pathogenesis by Garcia-Macia, Marina, Lopez-Fabuel, Irene, Buondelmonte, Constantina, Bonora, Nicolo, Morant-Ferrando, Brenda, Alonso-Batan, Paula, Vicente-Gutierrez, Carlos, Jimenez-Blasco, Daniel, Quintana-Cabrera, Ruben, Fernandez, Emilio, Storch, Stephan, Mole, Sara E., Almeida, Angeles, Bolaños, Juan P.

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Aberrant upregulation of the glycolytic enzyme PFKFB3 in CLN7 neuronal ceroid lipofuscinosis by Lopez-Fabuel, Irene, Garcia-Macia, Marina, Buondelmonte, Costantina, Burmistrova, Olga, Bonora, Nicolo, Alonso-Batan, Paula, Morant-Ferrando, Brenda, Vicente-Gutierrez, Carlos, Jimenez-Blasco, Daniel, Quintana-Cabrera, Ruben, Fernandez, Emilio, Llop, Jordi, Ramos-Cabrer, Pedro, Sharaireh, Aseel, Guevara-Ferrer, Marta, Fitzpatrick, Lorna, Thompton, Christopher D., McKay, Tristan R., Storch, Stephan, Medina, Diego L., Mole, Sara E., Fedichev, Peter O., Almeida, Angeles, Bolaños, Juan P.

“…CLN7 neuronal ceroid lipofuscinosis is an inherited lysosomal storage neurodegenerative disease highly prevalent in children. CLN7/MFSD8 gene encodes a…”
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Transcriptomic and metabolic signatures of neural cells cultured under a physiological-like environment by Fernandez, Emilio, Warde, Moussa, Manjarres-Raza, Israel, Bobo-Jimenez, Veronica, Martinez-Luna, Maria, Vicente-Gutierrez, Carlos, Garcia-Rodriguez, Dario, Jimenez-Blasco, Daniel, Almeida, Angeles, Bolaños, Juan P

“…Cultured brain cells are used conventionally to investigate fundamental neurobiology and identify therapeutic targets against neural diseases. However,…”
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Control of brain metabolism and behavior by cell-type specific mitochondrial CB1 receptors by Hebert-Chatelain, Etienne, Jimenez-Blasco, Daniel, Busquets-Garcia, Arnau, Serrat, Roman, Vicente-Gutierrez, Carlos, Lopez-Fabuel, Irene, Resch, Monica, Resel, Eva, Saraswat, Dave, Varilh, Marjorie, Cannich, Astrid, Rio, Itziar Bonilla-Del, Bellocchio, Luigi, Almeida, Angeles, Puente, Nagore, Lopez-Rodriguez, Maria-Luz, Lutz, Beat, Piazza, Pier-Vincenzo, Guzman, Manuel, Bouzier-Sore, Anne-Karine, Grandes, Pedro, Bolaños, Juan P., Marsicano, Giovanni

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Towards a distributed and real-time framework for robots: Evaluation of ROS 2.0 communications for real-time robotic applications by Gutiérrez, Carlos San Vicente, Juan, Lander Usategui San, Ugarte, Irati Zamalloa, Vilches, Víctor Mayoral

“…In this work we present an experimental setup to show the suitability of ROS 2.0 for real-time robotic applications. We disclose an evaluation of ROS 2.0…”
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Real-time Linux communications: an evaluation of the Linux communication stack for real-time robotic applications by Gutiérrez, Carlos San Vicente, Juan, Lander Usategui San, Ugarte, Irati Zamalloa, Vilches, Víctor Mayoral

“…As robotics systems become more distributed, the communications between different robot modules play a key role for the reliability of the overall robot…”
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