Search Results - "Vicen, Matej"
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Membrane and soluble endoglin role in cardiovascular and metabolic disorders related to metabolic syndrome
Published in Cellular and molecular life sciences : CMLS (01-03-2021)“…Membrane endoglin (Eng, CD105) is a transmembrane glycoprotein essential for the proper function of vascular endothelium. It might be cleaved by matrix…”
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MMP-12, Secreted by Pro-Inflammatory Macrophages, Targets Endoglin in Human Macrophages and Endothelial Cells
Published in International journal of molecular sciences (25-06-2019)“…Upon inflammation, monocyte-derived macrophages (MΦ) infiltrate blood vessels to regulate several processes involved in vascular pathophysiology. However,…”
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Long term effects of soluble endoglin and mild hypercholesterolemia in mice hearts
Published in PloS one (29-05-2020)“…Soluble endoglin (sEng) released into the circulation was suggested to be related to cardiovascular based pathologies. It was demonstrated that a combination…”
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Monoclonal anti-endoglin antibody TRC105 (carotuximab) prevents hypercholesterolemia and hyperglycemia-induced endothelial dysfunction in human aortic endothelial cells
Published in Frontiers in medicine (07-09-2022)“…Endoglin (Eng) is a co-receptor of the transforming growth factor β superfamily playing an important role in endothelial dysfunction. TRC105 (carotuximab) is a…”
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Regulation and role of endoglin in cholesterol‐induced endothelial and vascular dysfunction in vivo and in vitro
Published in The FASEB journal (01-05-2019)“…ABSTRACTOur objective was to investigate the effect of cholesterol [hypercholesterolemia and 7‐ketocholesterol (7K)] on endoglin (Eng) expression and…”
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Soluble endoglin and hypercholesterolemia aggravate endothelial and vessel wall dysfunction in mouse aorta
Published in Atherosclerosis (01-04-2018)“…Increased plasma levels of soluble endoglin (sEng) were detected in patients with endothelial dysfunction-related disorders and hypercholesterolemia. In this…”
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Soluble endoglin modulates the pro-inflammatory mediators NF-κB and IL-6 in cultured human endothelial cells
Published in Life sciences (1973) (15-04-2017)“…Endoglin is a transmembrane glycoprotein, that plays an important role in regulating endothelium. Proteolytic cleavage of membrane endoglin releases soluble…”
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Changes of membrane and soluble endoglin levels during early development of endothelial dysfunction in mice
Published in Atherosclerosis (01-08-2017)Get full text
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Soluble endoglin participate on the development of endothelial dysfunction: Or not?
Published in Atherosclerosis (01-08-2017)Get full text
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7-ketocholesterol treatment modulates expression of the cell adhesion molecules in human aortic endothelial cells-pilot study
Published in Atherosclerosis (01-08-2017)Get full text
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Soluble endoglin modulates the pro-inflammatory mediators NF-?B and IL-6 in cultured human endothelial cells
Published in Life sciences (1973) (15-04-2017)“…Aims Endoglin is a transmembrane glycoprotein, that plays an important role in regulating endothelium. Proteolytic cleavage of membrane endoglin releases…”
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Soluble Endoglin Combined with Hypercholesterolemia Affects Vascular and Endothelial Function in Mice
Published in Atherosclerosis. Supplements (01-06-2018)Get full text
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