Search Results - "Vicario, Nunzio"
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Connexins Signatures of the Neurovascular Unit and Their Physio-Pathological Functions
Published in International journal of molecular sciences (23-08-2022)“…Central nervous system (CNS) homeostasis is closely linked to the delicate balance of the microenvironment in which different cellular components of the…”
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2
Neural stem cells traffic functional mitochondria via extracellular vesicles
Published in PLoS biology (07-04-2021)“…Neural stem cell (NSC) transplantation induces recovery in animal models of central nervous system (CNS) diseases. Although the replacement of lost endogenous…”
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3
Neural stem cell transplantation in ischemic stroke: A role for preconditioning and cellular engineering
Published in Journal of cerebral blood flow and metabolism (01-07-2017)“…Ischemic stroke continues to be a leading cause of morbidity and mortality throughout the world. To protect and/or repair the ischemic brain, a multitiered…”
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4
The Biochemical and Pharmacological Properties of Ozone: The Smell of Protection in Acute and Chronic Diseases
Published in International journal of molecular sciences (01-02-2019)“…Ozone therapy has been widely used in everyday clinical practice over the last few years, leading to significant clinical results in the treatment of herniated…”
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5
Intercellular communication and ion channels in neuropathic pain chronicization
Published in Inflammation research (01-09-2020)“…Background Neuropathic pain is caused by primary lesion or dysfunction of either peripheral or central nervous system. Due to its complex pathogenesis, often…”
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Clobetasol promotes neuromuscular plasticity in mice after motoneuronal loss via sonic hedgehog signaling, immunomodulation and metabolic rebalancing
Published in Cell death & disease (16-06-2021)“…Motoneuronal loss is the main feature of amyotrophic lateral sclerosis, although pathogenesis is extremely complex involving both neural and muscle cells. In…”
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The Role of Epigenetics in Neuroinflammatory-Driven Diseases
Published in International journal of molecular sciences (02-12-2022)“…Neurodegenerative disorders are characterized by the progressive loss of central and/or peripheral nervous system neurons. Within this context,…”
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Lactate Rewrites the Metabolic Reprogramming of Uveal Melanoma Cells and Induces Quiescence Phenotype
Published in International journal of molecular sciences (20-12-2022)“…Uveal melanoma (UM), the most common primary intraocular cancer in adults, is among the tumors with poorer prognosis. Recently, the role of the oncometabolite…”
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Melatonin Enhances Neural Differentiation of Adipose-Derived Mesenchymal Stem Cells
Published in International journal of molecular sciences (01-05-2024)“…Adipose-derived mesenchymal stem cells (ASCs) are adult multipotent stem cells, able to differentiate toward neural elements other than cells of mesodermal…”
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10
Mu and Delta Opioid Receptor Targeting Reduces Connexin 43-Based Heterocellular Coupling during Neuropathic Pain
Published in International journal of molecular sciences (24-05-2022)“…Chronic neuropathic pain emerges from either central or peripheral lesions inducing spontaneous or amplified responses to non-noxious stimuli. Despite…”
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11
An Advanced, Silicon-Based Substrate for Sensitive Nucleic Acids Detection
Published in Sensors (Basel, Switzerland) (17-09-2018)“…Surface substrate and chemical functionalization are crucial aspects for the fabrication of the sensitive biosensor based on microarray technology. In this…”
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Glioblastoma mesenchymal subtype enhances antioxidant defence to reduce susceptibility to ferroptosis
Published in Scientific reports (05-09-2024)“…Glioblastoma (GBM) represents an aggressive brain tumor, characterized by intra- and inter-tumoral heterogeneity and therapy resistance, leading to…”
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13
Connexins in the Central Nervous System: Physiological Traits and Neuroprotective Targets
Published in Frontiers in physiology (18-12-2017)“…Cell-to-cell interaction and cell-to-extracellular environment communication are emerging as new therapeutic targets in neurodegenerative disorders. Dynamic…”
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14
Connexin expression decreases during adipogenic differentiation of human adipose-derived mesenchymal stem cells
Published in Molecular biology reports (01-12-2020)“…Adipose-derived stem cells (ASCs) represent a valuable tool for regenerative medicine being able to differentiate toward several cell lines, such as…”
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15
CXCL12/CXCR4 axis supports mitochondrial trafficking in tumor myeloma microenvironment
Published in Oncogenesis (New York, NY) (21-01-2022)“…Mesenchymal stromal cells (MSCs) within the protective microenvironment of multiple myeloma (MM) promote tumor growth, confer chemoresistance and support…”
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Anaplastic thyroid cancer cells reduce CD71 levels to increase iron overload tolerance
Published in Journal of translational medicine (03-11-2023)“…Abstract Background Follicular thyroid cancer (FTC) is a prevalent form of differentiated thyroid cancer, whereas anaplastic thyroid cancer (ATC) represents a…”
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17
Comparative evaluation of cigarette smoke and a heated tobacco product on microglial toxicity, oxidative stress and inflammatory response
Published in Journal of translational medicine (30-09-2024)“…Tobacco smoking is the leading cause of preventable death and disease worldwide, with over 8 million annual deaths attributed to cigarette smoking. This study…”
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Neuromuscular Plasticity in a Mouse Neurotoxic Model of Spinal Motoneuronal Loss
Published in International journal of molecular sciences (26-03-2019)“…Despite the relevant research efforts, the causes of amyotrophic lateral sclerosis (ALS) are still unknown and no effective cure is available. Many authors…”
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Lactate Induces the Expressions of MCT1 and HCAR1 to Promote Tumor Growth and Progression in Glioblastoma
Published in Frontiers in oncology (28-04-2022)“…The tumor microenvironment (TME) plays a pivotal role in establishing malignancy, and it is associated with high glycolytic metabolism and lactate release…”
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20
SRC Tyrosine Kinase Inhibitor and X-rays Combined Effect on Glioblastoma Cell Lines
Published in International journal of molecular sciences (01-06-2020)“…Glioblastoma (GBM) is one of the most lethal types of tumor due to its high recurrence level in spite of aggressive treatment regimens involving surgery,…”
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