Search Results - "Viault, Guillaume"

Endogenous metabolites of vitamin E limit inflammation by targeting 5-lipoxygenase by Pein, Helmut, Ville, Alexia, Pace, Simona, Temml, Veronika, Garscha, Ulrike, Raasch, Martin, Alsabil, Khaled, Viault, Guillaume, Dinh, Chau-Phi, Guilet, David, Troisi, Fabiana, Neukirch, Konstantin, König, Stefanie, Bilancia, Rosella, Waltenberger, Birgit, Stuppner, Hermann, Wallert, Maria, Lorkowski, Stefan, Weinigel, Christina, Rummler, Silke, Birringer, Marc, Roviezzo, Fiorentina, Sautebin, Lidia, Helesbeux, Jean-Jacques, Séraphin, Denis, Mosig, Alexander S., Schuster, Daniela, Rossi, Antonietta, Richomme, Pascal, Werz, Oliver, Koeberle, Andreas

“…Systemic vitamin E metabolites have been proposed as signaling molecules, but their physiological role is unknown. Here we show, by library screening of…”
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MixONat, a Software for the Dereplication of Mixtures Based on 13C NMR Spectroscopy by Bruguière, Antoine, Derbré, Séverine, Dietsch, Joël, Leguy, Jules, Rahier, Valentine, Pottier, Quentin, Bréard, Dimitri, Suor-Cherer, Sorphon, Viault, Guillaume, Le Ray, Anne-Marie, Saubion, Frédéric, Richomme, Pascal

“…Whether chemists or biologists, researchers dealing with metabolomics require tools to decipher complex mixtures. As a part of metabolomics and initially…”
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The first "ready-to-use" benzene-based heterotrifunctional cross-linker for multiple bioconjugation by Viault, Guillaume, Dautrey, Sébastien, Maindron, Nicolas, Hardouin, Julie, Renard, Pierre-Yves, Romieu, Anthony

“…The synthesis and applications of the first water-soluble benzene derivative bearing a set of three different and orthogonal bioconjugatable groups (aminooxy,…”
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Analogues of Natural Chalcones as Efficient Inhibitors of AKR1C3 by Möller, Gabriele, Temml, Veronika, Cala Peralta, Antonio, Gruet, Océane, Richomme, Pascal, Séraphin, Denis, Viault, Guillaume, Kraus, Luisa, Huber-Cantonati, Petra, Schopfhauser, Elisabeth, Pachmayr, Johanna, Tokarz, Janina, Schuster, Daniela, Helesbeux, Jean-Jacques, Dyar, Kenneth Allen

“…Naturally occurring substances are valuable resources for drug development. In this respect, chalcones are known to be antiproliferative agents against…”
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Stereoselective Synthesis of a Bicyclic Norsesquiterpene Backbone - A Possible Route to Nardosinane Derivatives by Selaïmia-Ferdjani, Ouassila, Kar, Anirban, Chavan, Sambhaji P., Horeau, Maxime, Viault, Guillaume, Pouessel, Jacky, Guillory, Xavier, Blot, Virginie, Tessier, Arnaud, Planchat, Aurelien, Jacquemin, Denis, Dubreuil, Didier, Pipelier, Muriel

“…We have developed an efficient diastereoselective synthetic route towards a nardosinane sesquiterpene scaffold. The strategy used a key bicyclic diene…”
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Hemisynthesis of selected embelin analogs and investigation of their proapoptotic activity against cancer cells by Viault, Guillaume, Babu, Katragadda Suresh, Gautier, Fabien, Barillé-Nion, Sophie, Juin, Philippe, Tasseau, Olivier, Grée, René

“…Embelin is a natural product, inhibitor of XIAP (X-chromosome-linked Inhibitor of APoptosis) with strong proapoptotic properties on cancer cells. In order to…”
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Asymmetric dearomative spirolactonization of naphthols using λ3-iodanes under chiral phase-transfer catalysis by Antien, Kevin, Viault, Guillaume, Pouységu, Laurent, Peixoto, Philippe, Quideau, Stéphane

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Xanthone Inhibitors of Unfolded Protein Response Isolated from Calophyllum caledonicum by Chambaud, Marine, Le Ray, Anne-Marie, Hamzi, Racha, Charpentier, Thomas, Blon, Nadège, Bréard, Dimitri, Le Pogam, Pierre, Litaudon, Marc, Dumontet, Vincent, Bataillé-Simoneau, Nelly, Guillemette, Thomas, Simoneau, Philippe, Schinkovitz, Andreas, Guilet, David, Viault, Guillaume, Richomme, Pascal

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Asymmetric dearomative spirolactonization of naphthols using λ3-iodanes under chiral phase-transfer catalysis by Antien, Kevin, Viault, Guillaume, Pouységu, Laurent, Peixoto, Philippe A., Quideau, Stéphane

“…The asymmetric phase-transfer catalytic effect of chiral Cinchona alkaloid-derived quaternary ammonium salts was investigated in the context of the…”
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Natural chalcones elicit formation of specialized pro-resolving mediators and related 15-lipoxygenase products in human macrophages by Kretzer, Christian, Jordan, Paul M., Meyer, Katharina P.L., Hoff, Daniel, Werner, Markus, Hofstetter, Robert Klaus, Koeberle, Andreas, Cala Peralta, Antonio, Viault, Guillaume, Seraphin, Denis, Richomme, Pascal, Helesbeux, Jean-Jacques, Stuppner, Hermann, Temml, Veronika, Schuster, Daniela, Werz, Oliver

“…[Display omitted] Specialized pro-resolving mediators (SPMs) comprise lipid mediators (LMs) produced from polyunsaturated fatty acids (PUFAs) via…”
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Design and validation of the first cell‐impermeant melatonin receptor agonist by Gbahou, Florence, Cecon, Erika, Viault, Guillaume, Gerbier, Romain, Jean‐Alphonse, Frederic, Karamitri, Angeliki, Guillaumet, Gérald, Delagrange, Philippe, Friedlander, Robert M, Vilardaga, Jean‐Pierre, Suzenet, Franck, Jockers, Ralf

“…Background and Purpose The paradigm that GPCRs are able to prolong or initiate cellular signalling through intracellular receptors recently emerged. Melatonin…”
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Natural Products Targeting the Fungal Unfolded Protein Response as an Alternative Crop Protection Strategy by Charpentier, Thomas, Viault, Guillaume, Le Ray, Anne-Marie, Bataillé-Simoneau, Nelly, Helesbeux, Jean-Jacques, Blon, Nadège, Bastide, Franck, Marchi, Muriel, Aligon, Sophie, Bruguière, Antoine, Dinh, Chau Phi, Benbelkacem, Zahia, Dallery, Jean-Felix, Simoneau, Philippe, Richomme, Pascal, Guillemette, Thomas

“…Discovering new solutions for crop protection is a major challenge for the next decades as a result of the ecotoxicological impact of classical fungicides, the…”
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Concise semisynthesis of novel phenazine-vitamin E hybrids via regioselective tocopheryl ortho-quinone formation by Viault, Guillaume, Helesbeux, Jean-Jacques, Richomme, Pascal, Séraphin, Denis

“…[Display omitted] •Concise semisynthetic route to phenazine-vitamin E hybrids.•IBX regio and chemoselective oxidation in vitamin E series.•Efficient IBX…”
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Xanthone Inhibitors of Unfolded Protein Response Isolated from Calophyllum caledonicum by Chambaud, Marine, Le Ray, Anne-Marie, Hamzi, Racha, Charpentier, Thomas, Blon, Nadège, Bréard, Dimitri, Le Pogam, Pierre, Litaudon, Marc, Dumontet, Vincent, Bataillé-Simoneau, Nelly, Guillemette, Thomas, Simoneau, Philippe, Schinkovitz, Andreas, Guilet, David, Viault, Guillaume, Richomme, Pascal

“…The unfolded protein response (UPR) is a key component of fungal virulence. The prenylated xanthone γ-mangostin isolated from Garcinia mangostana (Clusiaceae)…”
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MixONat, a Software for the Dereplication of Mixtures Based on 13 C NMR Spectroscopy by Bruguière, Antoine, Derbré, Séverine, Dietsch, Joël, Leguy, Jules, Rahier, Valentine, Pottier, Quentin, Bréard, Dimitri, Suor-Cherer, Sorphon, Viault, Guillaume, Le Ray, Anne-Marie, Saubion, Frédéric, Richomme, Pascal

“…Whether chemists or biologists, researchers dealing with metabolomics require tools to decipher complex mixtures. As a part of metabolomics and initially…”
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Structure-based design, semi-synthesis and anti-inflammatory activity of tocotrienolic amides as 5-lipoxygenase inhibitors by Dinh, Chau Phi, Ville, Alexia, Neukirch, Konstantin, Viault, Guillaume, Temml, Veronika, Koeberle, Andreas, Werz, Oliver, Schuster, Daniela, Stuppner, Hermann, Richomme, Pascal, Helesbeux, Jean-Jacques, Séraphin, Denis

“…Inflammation contributes to the development of various pathologies, e.g. asthma, cardiovascular diseases, some types of cancer, and metabolic disorders…”
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Real‐Time Analysis of Polyphenol–Protein Interactions by Surface Plasmon Resonance Using Surface‐Bound Polyphenols by Delannoy López, Daniela Mélanie, Tran, Dong Tien, Viault, Guillaume, Dairi, Sofiane, Peixoto, Philippe Alexandre, Capello, Yoan, Minder, Laëtitia, Pouységu, Laurent, Génot, Elisabeth, Di Primo, Carmelo, Deffieux, Denis, Quideau, Stéphane

“…A selection of bioactive polyphenols of different structural classes, such as the ellagitannins vescalagin and vescalin, the flavanoids catechin, epicatechin,…”
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Semisynthetic Vitamin E Derivatives as Potent Antibacterial Agents against Resistant Gram‐Positive Pathogens by Viault, Guillaume, Kempf, Marie, Ville, Alexia, Alsabil, Khaled, Perrot, Rodolphe, Richomme, Pascal, Hélesbeux, Jean‐Jacques, Séraphin, Denis

“…New 5‐substituted vitamin E derivatives were semisynthesized, and their antibacterial activity against human Gram‐positive and Gram‐negative pathogens was…”
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Exploration of Long-Chain Vitamin E Metabolites for the Discovery of a Highly Potent, Orally Effective, and Metabolically Stable 5‑LOX Inhibitor that Limits Inflammation by Neukirch, Konstantin, Alsabil, Khaled, Dinh, Chau-Phi, Bilancia, Rossella, Raasch, Martin, Ville, Alexia, Cerqua, Ida, Viault, Guillaume, Bréard, Dimitri, Pace, Simona, Temml, Veronika, Brunner, Elena, Jordan, Paul M, Marques, Marta C, Loeser, Konstantin, Gollowitzer, André, Permann, Stephan, Gerstmeier, Jana, Lorkowski, Stefan, Stuppner, Hermann, Garscha, Ulrike, Rodrigues, Tiago, Bernardes, Gonçalo J. L, Schuster, Daniela, Séraphin, Denis, Richomme, Pascal, Rossi, Antonietta, Mosig, Alexander S, Roviezzo, Fiorentina, Werz, Oliver, Helesbeux, Jean-Jacques, Koeberle, Andreas

“…Endogenous long-chain metabolites of vitamin E (LCMs) mediate immune functions by targeting 5-lipoxygenase (5-LOX) and increasing the systemic concentrations…”
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Efficient Semi-Synthesis of Natural δ‑(R)‑Tocotrienols from a Renewable Vegetal Source by Ville, Alexia, Viault, Guillaume, Hélesbeux, Jean-Jacques, Guilet, David, Richomme, Pascal, Séraphin, Denis

“…Recent studies have highlighted the biological potential of tocotrienols, a vitamin E subfamily. The major natural sources of tocotrienols are complex mixtures…”
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