Search Results - "Viappiani Cristiano"
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Insights on the Mechanical Properties of SARS-CoV-2 Particles and the Effects of the Photosensitizer Hypericin
Published in International journal of molecular sciences (10-08-2024)“…SARS-CoV-2 is a highly pathogenic virus responsible for the COVID-19 disease. It belongs to the Coronaviridae family, characterized by a phospholipid envelope,…”
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2
Tetramethylbenzidine: An Acoustogenic Photoacoustic Probe for Reactive Oxygen Species Detection
Published in Sensors (Basel, Switzerland) (21-10-2020)“…Photoacoustic imaging is attracting a great deal of interest owing to its distinct advantages over other imaging techniques such as fluorescence or magnetic…”
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3
Concanavalin A Delivers a Photoactive Protein to the Bacterial Wall
Published in International journal of molecular sciences (01-06-2024)“…Modular supramolecular complexes, where different proteins are assembled to gather targeting capability and photofunctional properties within the same…”
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4
Experimental basis for a new allosteric model for multisubunit proteins
Published in Proceedings of the National Academy of Sciences - PNAS (02-09-2014)“…Monod, Wyman, and Changeux (MWC) explained allostery in multisubunit proteins with a widely applied theoretical model in which binding of small molecules,…”
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5
A Photoactive Supramolecular Complex Targeting PD-L1 Reveals a Weak Correlation between Photoactivation Efficiency and Receptor Expression Levels in Non-Small-Cell Lung Cancer Tumor Models
Published in Pharmaceutics (01-12-2023)“…Photo-immunotherapy uses antibodies conjugated to photosensitizers to produce nanostructured constructs endowed with targeting properties and…”
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6
Targeted photoimmunotherapy for cancer
Published in Biomolecular Concepts (19-03-2022)“…Photodynamic therapy (PDT) is a clinically approved procedure that can exert a curative action against malignant cells. The treatment implies the…”
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Experiments on Hemoglobin in Single Crystals and Silica Gels Distinguish among Allosteric Models
Published in Biophysical journal (15-09-2015)“…Trapping quaternary structures of hemoglobin in single crystals or by encapsulation in silica gels has provided a demanding set of data to test statistical…”
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Mycobacterial and Human Ferrous Nitrobindins: Spectroscopic and Reactivity Properties
Published in International journal of molecular sciences (07-02-2021)“…Structural and functional properties of ferrous ( -Nb) and human ( -Nb) nitrobindins (Nbs) were investigated. At pH 7.0 and 25.0 °C, the unliganded Fe(II)…”
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Subdiffraction localization of a nanostructured photosensitizer in bacterial cells
Published in Scientific reports (23-10-2015)“…Antibacterial treatments based on photosensitized production of reactive oxygen species is a promising approach to address local microbial infections. Given…”
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10
Unusually Fast bis -Histidyl Coordination in a Plant Hemoglobin
Published in International journal of molecular sciences (08-03-2021)“…The recently identified nonsymbiotic hemoglobin gene of the legume possesses unique properties as it generates four alternative splice forms encoding proteins…”
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A photosensitizing fusion protein with targeting capabilities
Published in Biomolecular Concepts (29-03-2022)“…The photodynamic treatment for antimicrobial applications or anticancer therapy relies on reactive oxygen species generated by photosensitizing molecules after…”
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12
A red-green photochromic bacterial protein as a new contrast agent for improved photoacoustic imaging
Published in Photoacoustics (Munich) (01-06-2022)“…The GAF3 domain of the cyanobacteriochrome Slr1393 from Synechocystis sp. PCC6803, binding phycocyanobilin as a chromophore, shows photochromicity between two…”
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13
The dark recovery rate in the photocycle of the bacterial photoreceptor YtvA is affected by the cellular environment and by hydration
Published in PloS one (11-09-2014)“…We report thermal recovery kinetics of the lit state into the parental dark state, measured for the blue light-sensing photoreceptor YtvA inside overexpressing…”
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14
Electrostatic Tuning of the Ligand Binding Mechanism by Glu27 in Nitrophorin 7
Published in Scientific reports (18-07-2018)“…Nitrophorins (NP) 1–7 are NO-carrying heme proteins found in the saliva of the blood-sucking insect Rhodnius prolixus . The isoform NP7 displays peculiar…”
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The Greenland shark Somniosus microcephalus-Hemoglobins and ligand-binding properties
Published in PloS one (12-10-2017)“…A large amount of data is currently available on the adaptive mechanisms of polar bony fish hemoglobins, but structural information on those of cartilaginous…”
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Photochromic conversion in a red/green cyanobacteriochrome from Synechocystis PCC6803: quantum yields in solution and photoswitching dynamics in living E. coli cells
Published in Photochemical & photobiological sciences (01-02-2015)“…The protein encoded by the gene slr1393 from the cyanobacterium Synechocystis sp. PCC6803 (Slr1393) is composed of three GAF domains, a PAS domain, and a…”
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17
Ligand migration through the internal hydrophobic cavities in human neuroglobin
Published in Proceedings of the National Academy of Sciences - PNAS (10-11-2009)“…Neuroglobin (Ngb), a member of the globin superfamily, was found in the brain of vertebrates and is suggested to play a neuroprotective function under hypoxic…”
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Nitric Oxide Sensing by a Blue Fluorescent Protein
Published in Antioxidants (01-11-2022)“…S-Nitrosylation of cysteine residues is an important molecular mechanism for dynamic, post-translational regulation of several proteins, providing a ubiquitous…”
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Ligand migration through hemeprotein cavities: insights from laser flash photolysis and molecular dynamics simulations
Published in Physical chemistry chemical physics : PCCP (14-07-2013)“…The presence of cavities and tunnels in the interior of proteins, in conjunction with the structural plasticity arising from the coupling to the thermal…”
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Evolution of allosteric models for hemoglobin
Published in IUBMB life (2007)“…We compare various allosteric models that have been proposed to explain cooperative oxygen binding to hemoglobin, including the two‐state allosteric model of…”
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