Search Results - "Viana, Ricardo J.S"

Bile acids: regulation of apoptosis by ursodeoxycholic acid by Amaral, Joana D., Viana, Ricardo J.S., Ramalho, Rita M., Steer, Clifford J., Rodrigues, Cecília M.P.

“…Bile acids are a group of molecular species of acidic steroids with peculiar physical-chemical and biological characteristics. At high concentrations they…”
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Bile acids and apoptosis modulation: an emerging role in experimental Alzheimer's disease by Ramalho, Rita M, Viana, Ricardo J.S, Low, Walter C, Steer, Clifford J, Rodrigues, Cecília M.P

“…The potential role of apoptosis in Alzheimer's disease (AD) has been an area of intense research in recent years. Ursodeoxycholic acid (UDCA) and its…”
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Organelle stress sensors and cell death mechanisms in neurodegenerative diseases by Viana, Ricardo J S, Fonseca, Maria B, Ramalho, Rita M, Nunes, Ana F, Rodrigues, Cecília M P

“…Neurodegenerative diseases trigger neuronal cell death by a variety of endogenous suicide pathways. Although cell death may occur through highly heterogeneous…”
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TUDCA, a Bile Acid, Attenuates Amyloid Precursor Protein Processing and Amyloid-β Deposition in APP/PS1 Mice by Nunes, Ana F., Amaral, Joana D., Lo, Adrian C., Fonseca, Maria B., Viana, Ricardo J. S., Callaerts-Vegh, Zsuzsanna, D’Hooge, Rudi, Rodrigues, Cecília M. P.

“…Alzheimer’s disease (AD) is a neurodegenerative disorder characterized by accumulation of amyloid-β (Aβ) peptide in the hippocampus and frontal cortex of the…”
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Endoplasmic Reticulum Enrollment in Alzheimer’s Disease by Viana, Ricardo J. S., Nunes, Ana F., Rodrigues, Cecília M. P.

“…Alzheimer’s disease (AD) poses a huge challenge for society and health care worldwide as molecular pathogenesis of the disease is poorly understood and…”
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Amyloid-β peptide-induced secretion of endoplasmic reticulum chaperone glycoprotein GRP94 by Viana, Ricardo J S, Steer, Clifford J, Rodrigues, Cecília M P

“…Amyloid-β (Aβ) peptide-induced neurotoxicity is typically associated with cell death through mechanisms not entirely understood. Here, we investigated stress…”
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Modulation of amyloid-β peptide-induced toxicity through inhibition of JNK nuclear localization and caspase-2 activation by Viana, Ricardo J S, Ramalho, Rita M, Nunes, Ana F, Steer, Clifford J, Rodrigues, Cecília M P

“…Amyloid-β (Aβ) peptide- induced neurotoxicity is typically associated with apoptosis. In previous studies, we have shown that tauroursodeoxycholic acid…”
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Apoptosis in transgenic mice expressing the P301L mutated form of human tau by Ramalho, Rita M, Viana, Ricardo J S, Castro, Rui E, Steer, Clifford J, Low, Walter C, Rodrigues, Cecília M P

“…The rTg4510 mouse is a tauopathy model, characterized by massive neurodegeneration in Alzheimer's disease (AD)-relevant cortical and limbic structures,…”
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Naphtho[2,3- d]isoxazole-4,9-dione-3-carboxylates: Potent, non-cytotoxic, antiapoptotic agents by Santos, Daniela M., Santos, Maria M.M., Viana, Ricardo J.S., Castro, Rui E., Moreira, Rui, Rodrigues, Cecília M.P.

“…Compounds containing a quinone moiety represent an important class of biologically active molecules that are widespread in nature, displaying anticancer,…”
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