Search Results - "Viana, Gustavo H.R."
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1
Antifungal activity of a novel 3-Alkylpyridine analog derived from Marine sponge alkaloids
Published in Anais da Academia Brasileira de Ciências (01-01-2021)“…Abstract Candida spp. is considered an important cause of healthcare-associated infections worldwide. Currently, the emergence and spread of resistant Candida…”
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2
Microwave-promoted synthesis of chiral pyridinium salts
Published in Tetrahedron letters (07-11-2005)“…The synthesis of several chiral pyridinium salts via Zincke’s reaction can be easily accomplished by microwave oven irradiation. Yield enhancements, shorter…”
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A 3-alkylpyridine-bearing alkaloid exhibits potent antimicrobial activity against methicillin-resistant Staphylococcus aureus (MRSA) with no detectable resistance
Published in Microbiological research (01-08-2022)“…Staphylococcus aureus is a Gram-positive bacterium responsible for a wide variety of infectious diseases, and its methicillin-resistant isolates pose a serious…”
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4
Antibacterial and antibiofilm activities of synthetic analogs of 3-alkylpyridine marine alkaloids
Published in Medicinal chemistry research (01-06-2020)“…Nowadays, the emergence of superbugs is one of the most serious public health problems. Strains of Staphylococcus aureus and Klebsiella pneumoniae , resistant…”
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5
Revealing the Binding Process of New 3‑Alkylpyridine Marine Alkaloid Analogue Antimalarials and the Heme Group: An Experimental and Theoretical Investigation
Published in Journal of chemical information and modeling (28-03-2016)“…Synthetic 3-alkylpyridine marine alkaloid (3-APA) analogues have shown good antimalarial activity against Plasmodium falciparum . However, despite their…”
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6
Synthesis, cytotoxic activity, and mode of action of new Santacruzamate A analogs
Published in Medicinal chemistry research (01-12-2018)“…Breast and ovarian cancer are the most common cancers in women. Available cancer treatments, in general, have limited efficacy and frequent, undesirable side…”
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7
Design and synthesis of new chacones substituted with azide/triazole groups and analysis of their cytotoxicity towards HeLa cells
Published in Molecules (Basel, Switzerland) (29-08-2012)“…A series of new chalcones substituted with azide/triazole groups were designed and synthesized, and their cytotoxic activity was evaluated in vitro against the…”
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Synthesis and in vitro evaluation of novel triazole/azide chalcones
Published in Medicinal chemistry research (2017)“…A series of 30 novel triazole/azide chalcone derivatives were synthesized by Claisen-Schmidt and Cu(I)-catalyzed cycloaddition reactions. The antiproliferative…”
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Synthesis and Evaluation of Antimalarial Activity of Oxygenated 3-alkylpyridine Marine Alkaloid Analogues
Published in Chemical biology & drug design (01-09-2011)“…A series of new oxygenated analogues of marine 3‐alkylpyridine alkaloids were prepared from 3‐pyridinepropanol in few steps and in good yields. The key step…”
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10
Cytotoxicity evaluation of marine alkaloid analogues of viscosaline and theonelladin C
Published in Biomedicine & preventive nutrition (01-04-2012)“…A series of new oxygenated analogues of marine 3-alkylpyridine alkaloids were prepared from 3-pyridinepropanol in few steps and in good yields. The compounds…”
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