Search Results - "Viana, Gustavo H. R."

Revealing the Binding Process of New 3‑Alkylpyridine Marine Alkaloid Analogue Antimalarials and the Heme Group: An Experimental and Theoretical Investigation by Ribeiro-Viana, Renato M, Butera, Anna P, Santos, Eliziane S, Tischer, César A, Alves, Rosemeire B, Pereira de Freitas, Rossimiriam, Guimarães, Luciana, Varotti, Fernando P, Viana, Gustavo H. R, Nascimento, Clebio S

“…Synthetic 3-alkylpyridine marine alkaloid (3-APA) analogues have shown good antimalarial activity against Plasmodium falciparum . However, despite their…”
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Design and synthesis of new chacones substituted with azide/triazole groups and analysis of their cytotoxicity towards HeLa cells by da Silva, Graziele D, da Silva, Marina G, Souza, Estrela M P V E, Barison, Andersson, Simões, Sarah C, Varotti, Fernando P, Barbosa, Leandro A, Viana, Gustavo H R, Villar, José A F P

“…A series of new chalcones substituted with azide/triazole groups were designed and synthesized, and their cytotoxic activity was evaluated in vitro against the…”
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Synthesis and Evaluation of Antimalarial Activity of Oxygenated 3-alkylpyridine Marine Alkaloid Analogues by Hilário, Flaviane F., de Paula, Renata Cristina, Silveira, Mariana L. T., Viana, Gustavo H. R., Alves, Rosemeire B., Pereira, Juliana R. C. S., Silva, Luciana Maria, de Freitas, Rossimiriam P., de Pilla Varotti, Fernando

“…A series of new oxygenated analogues of marine 3‐alkylpyridine alkaloids were prepared from 3‐pyridinepropanol in few steps and in good yields. The key step…”
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A 3-alkylpyridine-bearing alkaloid exhibits potent antimicrobial activity against methicillin-resistant Staphylococcus aureus (MRSA) with no detectable resistance by Herrera, Karina M.S., Lopes, Gabriela F.M., Oliveira, Michael E., Sousa, Jaqueline F., Lima, William G., Silva, Fernanda K., Brito, Júlio C.M., Gomes, Ana Júlia P.S., Viana, Gustavo H.R., Soares, Adriana C., Ferreira, Jaqueline M.S.

“…Staphylococcus aureus is a Gram-positive bacterium responsible for a wide variety of infectious diseases, and its methicillin-resistant isolates pose a serious…”
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Antifungal activity of a novel 3-Alkylpyridine analog derived from Marine sponge alkaloids by ANDRADE, JÉSSICA T., LIMA, WILLIAM G., BARBOSA, CAMILA S., GONÇALVES, ALESSANDRA M.M.N., SILVA, MAYRA K.P., MORAIS, FERNANDA B., PALUMBO, JULIANA M.C., VIANA, GUSTAVO H.R., FERREIRA, JAQUELINE M.S.

“…Abstract Candida spp. is considered an important cause of healthcare-associated infections worldwide. Currently, the emergence and spread of resistant Candida…”
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Synthesis, cytotoxic activity, and mode of action of new Santacruzamate A analogs by Andrade, Silmara N., Evangelista, Fernanda C. G., Seckler, Diego, Marques, Deisielly R., Freitas, Túlio R., Nunes, Renata R., Oliveira, Júlia T., Ribeiro, Rosy I. M. A., Santos, Hélio B., Thomé, Ralph G., Taranto, Alex G., Santos, Fabio V., Viana, Gustavo H. R., Freitas, Rossimiriam P., Humberto, Jorge L., Sabino, Adriano de P., Hilário, Flaviane F., Varotti, Fernando P.

“…Breast and ovarian cancer are the most common cancers in women. Available cancer treatments, in general, have limited efficacy and frequent, undesirable side…”
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Synthesis and in vitro evaluation of novel triazole/azide chalcones by Evangelista, Fernanda C. G., Bandeira, Maralice O., Silva, Graziele D., Silva, Marina G., Andrade, Silmara N., Marques, Deisielly R., Silva, Luciana M., Castro, Whocely V., Santos, Fabio V., Viana, Gustavo H. R., Villar, José A. F. P., Sabino, Adriano P., Varotti, Fernando P.

“…A series of 30 novel triazole/azide chalcone derivatives were synthesized by Claisen-Schmidt and Cu(I)-catalyzed cycloaddition reactions. The antiproliferative…”
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Antibacterial and antibiofilm activities of synthetic analogs of 3-alkylpyridine marine alkaloids by Herrera, Karina M. S., da Silva, Fernanda K., de Lima, William G., Barbosa, Camila de S., Gonçalves, Alessandra M. M. N., Viana, Gustavo H. R., Soares, Adriana C., Ferreira, Jaqueline M. S.

“…Nowadays, the emergence of superbugs is one of the most serious public health problems. Strains of Staphylococcus aureus and Klebsiella pneumoniae , resistant…”
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