Search Results - "Vian, Laurence"
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Glutathione S-transferase M1 and multidrug resistance protein 1 act in synergy to protect melanoma cells from vincristine effects
Published in Molecular pharmacology (01-04-2004)“…Previous studies have shown that glutathione S-transferases (GSTs) can operate in synergy with efflux transporters, multi-drug resistance proteins (MRPs), to…”
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Activity of ethanolic extracts leaves of Machaerium floribundum against acne-inducing bacteria, and their cytoprotective and antioxidant effects on fibroblast
Published in Revista peruana de biología (01-08-2011)“…Propionibacterium acnes, Staphylococcus epidermidis and Staphylococcus aureus have been recognized as the bacteria that are involved in the inflammatory…”
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In vitro detection of indirect-acting genotoxins in the comet assay using Hep G2 cells
Published in Mutation research (10-07-2000)“…The induction of DNA damage by four known promutagens (cyclophosphamide (CP), benzo( a)pyrene (BP), dimethylbenz( a)anthracene and 2-acetylaminofluorene (2AAF)…”
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Cytotoxicity, DNA damage, and apoptosis induced by new fotemustine analogs on human melanoma cells in relation to O6-methylguanine DNA-methyltransferase expression
Published in The Journal of pharmacology and experimental therapeutics (01-11-2003)“…Fotemustine is a third generation chloroethylnitrosourea that has demonstrated significant antitumoral effects in malignant melanoma. However, its use is…”
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The influence of alcohol, propylene glycol and 1,2-pentanediol on the permeability of hydrophilic model drug through excised pig skin
Published in International journal of pharmaceutics (05-06-2009)“…Alcohol and glycol including 1,2-pentanediol, a new product in this field, were examined for their transdermal penetration enhancing in vitro properties using…”
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Enhancement of 5-fluorouracil cytotoxicity by human thymidine-phosphorylase expression in cancer cells:In vitro andIn vivo study
Published in International journal of cancer (29-01-1999)“…Transferring a gene into cancer cells in order to sensitize them to drugs is an important approach in human cancer gene-therapy research. Thymidine…”
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Lysosomes and unfolded protein response, determinants of differential resistance of melanoma cells to vinca alkaloids
Published in Fundamental & clinical pharmacology (01-04-2015)“…On account of its strong ability to become chemoresistant after a primary response to drugs, malignant melanoma (MM) remains a therapeutic challenge. This…”
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Differential involvement of glutathione S-transferase mu 1 and multidrug resistance protein 1 in melanoma acquired resistance to vinca alkaloids
Published in Fundamental & clinical pharmacology (01-02-2015)“…On account of its extreme intrinsic resistance to apoptosis and of its strong ability to become chemoresistant after a primary response to drugs, malignant…”
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Irradiation of Skin and Contrasting Effects on Absorption of Hydrophilic and Lipophilic Compounds
Published in Photochemistry and photobiology (01-11-2009)“…Increasing legal requirements for risk assessment and efficacy testing in the dermo‐cosmetic field have led to the development of alternative test methods. In…”
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O(6)-methylguanine DNA-methyltransferase (MGMT) overexpression in melanoma cells induces resistance to nitrosoureas and temozolomide but sensitizes to mitomycin C
Published in Toxicology and applied pharmacology (01-03-2006)“…Alkylating agents play an important role in the chemotherapy of malignant melanomas. The activity of alkylating agents depends on their capacity to form alkyl…”
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O 6-methylguanine DNA-methyltransferase (MGMT) overexpression in melanoma cells induces resistance to nitrosoureas and temozolomide but sensitizes to mitomycin C
Published in Toxicology and applied pharmacology (01-03-2006)“…Alkylating agents play an important role in the chemotherapy of malignant melanomas. The activity of alkylating agents depends on their capacity to form alkyl…”
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Activity of ethanolic extracts leaves of Machaerium floribundum against acne-inducing bacteria, and their cytoprotective and antioxidant effects on fibroblast/Actividad del extracto etanólico de las hojas de Machaerium floribundum contra bacterias que inducen el acné y su efecto citoprotector y antioxidante sobre fibroblastos
Published in Revista peruana de biología (01-08-2011)Get full text
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The cytokine-dependent MUTZ-3 cell line as an in vitro model for the screening of contact sensitizers
Published in Toxicology and applied pharmacology (01-04-2006)“…Langerhans cells (LC) are key mediators of contact allergenicity in the skin. However, no in vitro methods exist which are based on the activation process of…”
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Enhancement of 5‐fluorouracil cytotoxicity by human thymidine‐phosphorylase expression in cancer cells: In vitro and In vivo study
Published in International journal of cancer (29-01-1999)“…Transferring a gene into cancer cells in order to sensitize them to drugs is an important approach in human cancer gene‐therapy research. Thymidine…”
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16
Qualitative and quantitative evaluation of a local lymph node assay based on ex vivo interleukin-2 production
Published in Toxicology (Amsterdam) (15-01-2005)“…The local lymph node assay (LLNA) is a regular method for the detection of sensitizing chemicals in mice which measures the incorporation of tritiated…”
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Skin Constituents as Cosmetic Ingredients. Part I: A Study of Bio-mimetic Monoglycerides Behavior at the Squalene-Water Interface by the "Pendant Drop" Method in a Static Mode
Published in Journal of dispersion science and technology (01-09-2006)“…This work presents the behavior of bio-mimetic monoglycerides at the squalene/water interface. The study was done in the so-called "static" mode using the…”
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Le site de référence du Partenariat européen d’innovation pour un vieillissement actif et en bonne santé MACVIA-LR (contre les maladies chroniques pour un vieillissement en bonne santé en Languedoc-Roussillon)
Published in La Presse médicale (1983) (01-11-2015)“…Le site de référence du Partenariat européen d'innovation pour un vieillissement actif et en bonne santé MACVIA-LR (contre les maladies chroniques pour un…”
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Skin Constituents as Cosmetic Ingredients. Part II: A Study of Bio-Mimetic Monoglycerides Behavior at the Squalene-Water Interface by the "Pendant Drop" Method in a Dynamic Mode
Published in Journal of dispersion science and technology (01-09-2006)“…This work aims at presenting the viscoelastic behavior of bio-mimetic monoglycerides used as emulsifier in a mixture made of two non-miscible liquids, squalene…”
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Actividad del extracto etanolico de las hojas de Machaerium floribundum contra bacterias que inducen el acne y su efecto citoprotector y antioxidante sobre fibroblastos
Published in Revista peruana de biología (01-08-2011)“…Propionibacterium acnes, Staphylococcus epidermidis y Staphylococcus aureus han sido reconocidas como las bacterias involucradas en el proceso inflamatorio del…”
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