Search Results - "Vial, Sarah C. M."

Mechanism of glycogen synthase inactivation and interaction with glycogenin by Marr, Laura, Biswas, Dipsikha, Daly, Leonard A., Browning, Christopher, Vial, Sarah C. M., Maskell, Daniel P., Hudson, Catherine, Bertrand, Jay A., Pollard, John, Ranson, Neil A., Khatter, Heena, Eyers, Claire E., Sakamoto, Kei, Zeqiraj, Elton

“…Glycogen is the major glucose reserve in eukaryotes, and defects in glycogen metabolism and structure lead to disease. Glycogenesis involves interaction of…”
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Crystal structure of the Pseudomonas aeruginosa MurG: UDP-GlcNAc substrate complex by Brown, Kieron, Vial, Sarah C M, Dedi, Neesha, Westcott, James, Scally, Stephen, Bugg, Timothy D H, Charlton, Peter A, Cheetham, Graham M T

“…MurG is an essential bacterial glycosyltransferase enzyme in Pseudomonas aeruginosa performing one of the key membrane steps of peptidoglycan synthesis…”
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Crystal Structures of Interleukin-2 Tyrosine Kinase and Their Implications for the Design of Selective Inhibitors by Brown, Kieron, Long, Joanna M, Vial, Sarah C M, Dedi, Neesha, Dunster, Nicholas J, Renwick, Suzanne B, Tanner, Adam J, Frantz, J Dan, Fleming, Mark A, Cheetham, Graham M T

“…Interleukin-2 tyrosine kinase, Itk, is an important member of the Tec family of non-receptor tyrosine kinases that play a central role in signaling through…”
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Structural Basis for the Interaction of TAK1 Kinase with its Activating Protein TAB1 by Brown, Kieron, Vial, Sarah C.M., Dedi, Neesha, Long, Joanna M., Dunster, Nicholas J., Cheetham, Graham M.T.

“…Transforming growth factor-β (TGF-β)-activated kinase 1 (TAK1) is a member of the MAPKKK family of protein kinases, and is involved in intracellular signalling…”
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