Search Results - "Viaggi, Cristina"
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Grafted Neural Precursors Integrate Into Mouse Striatum, Differentiate and Promote Recovery of Function Through Release of Erythropoietin in MPTP-Treated Mice
Published in ASN neuro (01-10-2016)“…Erythropoietin-releasing neural precursor cells (Er-NPCs) are a subclass of subventricular zone-derived neural progenitors, capable of surviving for 6 hr after…”
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Behavioral, Neurochemical, and Electrophysiological Changes in an Early Spontaneous Mouse Model of Nigrostriatal Degeneration
Published in Neurotoxicity research (01-08-2011)“…In idiopathic Parkinson’s disease, clinical symptoms do not emerge until consistent neurodegeneration has occurred. The late appearance of symptoms implies the…”
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Characterization of the Engrailed mutant mice as experimental models for Parkinson's disease
Published in Parkinsonism & related disorders (2008)“…Abstract Engrailed genes are homeodomain-containing transcription factors necessary for the development and maintenance of mesencephalic dopaminergic neurons…”
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Glial cells are affected more than interneurons by the loss of Engrailed 2 gene in the mouse cerebellum
Published in Journal of anatomy (01-04-2024)“…Glial cells play a pivotal role in the inflammatory processes, which are common features of several neurodevelopmental and neurodegenerative disorders. Their…”
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5
Morphological alterations of the reticular thalamic nucleus in Engrailed‐2 knockout mice
Published in Journal of anatomy (01-05-2020)“…The reticular thalamic nucleus (Rt) is a sheet of neurons that surrounds the dorsal thalamus laterally, along its dorso‐ventral and rostro‐caudal axes. It…”
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Melanocortin receptor 4 as a new target in melanoma therapy: Anticancer activity of the inhibitor ML00253764 alone and in association with B-raf inhibitor vemurafenib
Published in Biochemical pharmacology (01-01-2024)“…The aim of our study is to investigate in vitro and in vivo MC4R as a novel target in melanoma using the selective antagonist ML00253764 (ML) alone and in…”
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Pharmacological Strategies for Bipolar Disorders in Acute Phases and Chronic Management with a Special Focus on Lithium, Valproic Acid, and Atypical Antipsychotics
Published in Current neuropharmacology (01-01-2023)“…Bipolar disorders (BDs) are a heterogeneous group of severe affective disorders generally described by the alternation of (hypo)manic, depressive, and mixed…”
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Recovery from experimental parkinsonism by intrastriatal application of erythropoietin or EPO-releasing neural precursors
Published in Neuropharmacology (01-06-2017)“…An extensive literature has shown a powerful neuroprotective action of Erythropoietin (EPO) both in vivo and in vitro. This study shows that EPO, whether…”
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6-Hydroxydopamine lesion in the ventral tegmental area fails to reduce extracellular dopamine in the cerebral cortex
Published in Journal of neuroscience research (15-05-2008)“…Dopamine and noradrenaline are both involved in modulation of superior cognitive functions that are mainly dependent on frontal cortex activity. Experimental…”
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Serotonin abnormalities in Engrailed-2 knockout mice: New insight relevant for a model of Autism Spectrum Disorder
Published in Neurochemistry international (01-08-2015)“…•Engrailed 2 knockout mice, new insight relevant for Autism Spectrum Disorder.•Serotonin system alterations in En2 knockout mice are in agreement with…”
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Pharmacological Strategies for Bipolar Disorders in Acute Phases and Chronic Management with a Special Focus on Lithium, Valproic Acid, and Atypical Antipsychotics
Published in Current neuropharmacology (2022)“…Bipolar disorders (BDs) are a heterogeneous group of severe affective disorders generally described by the alternation of (hypo)manic, depressive, and mixed…”
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12
Fluorescent light induces neurodegeneration in the rodent nigrostriatal system but near infrared LED light does not
Published in Brain research (01-05-2017)“…Highlights • Fluorescent light causes degeneration of dopamine neurons in substantia nigra. • Light at 710 nm does not cause degeneration of dopamine neurons…”
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Clarifying CLARITY: Quantitative Optimization of the Diffusion Based Delipidation Protocol for Genetically Labeled Tissue
Published in Frontiers in neuroscience (25-04-2016)“…Tissue clarification has been recently proposed to allow deep tissue imaging without light scattering. The clarification parameters are somewhat arbitrary and…”
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Bright light exposure reduces TH-positive dopamine neurons: implications of light pollution in Parkinson's disease epidemiology
Published in Scientific reports (06-03-2013)“…This study explores the effect of continuous exposure to bright light on neuromelanin formation and dopamine neuron survival in the substantia nigra …”
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15
Acetaldehyde and parkinsonism: role of CYP450 2E1
Published in Frontiers in behavioral neuroscience (21-06-2013)“…The present review update the relationship between acetaldehyde (ACE) and parkinsonism with a specific focus on the role of P450 system and CYP 2E1 isozyme…”
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Apomorphine offers new insight into dopaminergic neuron vulnerability in mesencephalic cultures
Published in Neuropharmacology (01-10-2008)“…The mechanism by which the dopamine neurons of the substantia nigra pars compacta degenerate in Parkinson's disease, is partly unknown. Dopamine could be…”
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Involvement of cytochrome P450 2E1 in the 1‐methyl‐4‐phenyl‐1,2,3,6‐tetrahydropyridine‐induced mouse model of Parkinson's disease
Published in Journal of neurochemistry (01-10-2004)“…Elucidation of the biochemical steps leading to the 1‐methyl‐4‐phenyl‐1,2,3,6‐tetrahydropyridine (MPTP)‐induced degeneration of the nigrostriatal dopamine (DA)…”
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18
Ethanol intake and ethanol-induced locomotion and locomotor sensitization in Cyp2e1 knockout mice
Published in Pharmacogenetics and genomics (01-03-2009)“…OBJECTIVESIt has been shown that acetaldehyde is an active metabolite of ethanol with central actions that modulate behavior. Catalase has been proposed as the…”
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Role of CYP2E1 in the mouse model of MPTP toxicity
Published in Parkinsonism & related disorders (2008)“…Abstract It has been shown that diethyldithiocarbamate (DDC) potentiates 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) toxicity in mice as a result of…”
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Cytochrome p450 and parkinsonism: protective role of CYP2E1
Published in Functional neurology (2001)Get more information
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