Search Results - "Via, E"

High Persister Mutants in Mycobacterium tuberculosis by Torrey, Heather L, Keren, Iris, Via, Laura E, Lee, Jong Seok, Lewis, Kim

“…Mycobacterium tuberculosis forms drug-tolerant persister cells that are the probable cause of its recalcitrance to antibiotic therapy. While genetically…”
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Absolute Quantitative MALDI Imaging Mass Spectrometry: A Case of Rifampicin in Liver Tissues by Chumbley, Chad W, Reyzer, Michelle L, Allen, Jamie L, Marriner, Gwendolyn A, Via, Laura E, Barry, Clifton E, Caprioli, Richard M

“…Matrix-assisted laser desorption/ionization (MALDI) imaging mass spectrometry (IMS) elucidates molecular distributions in thin tissue sections. Absolute…”
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Tuberculosis drugs' distribution and emergence of resistance in patient's lung lesions: A mechanistic model and tool for regimen and dose optimization by Strydom, Natasha, Gupta, Sneha V, Fox, William S, Via, Laura E, Bang, Hyeeun, Lee, Myungsun, Eum, Seokyong, Shim, TaeSun, Barry, 3rd, Clifton E, Zimmerman, Matthew, Dartois, Véronique, Savic, Radojka M

“…The sites of mycobacterial infection in the lungs of tuberculosis (TB) patients have complex structures and poor vascularization, which obstructs drug…”
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Host-directed therapy of tuberculosis based on interleukin-1 and type I interferon crosstalk by Mayer-Barber, Katrin D., Andrade, Bruno B., Oland, Sandra D., Amaral, Eduardo P., Barber, Daniel L., Gonzales, Jacqueline, Derrick, Steven C., Shi, Ruiru, Kumar, Nathella Pavan, Wei, Wang, Yuan, Xing, Zhang, Guolong, Cai, Ying, Babu, Subash, Catalfamo, Marta, Salazar, Andres M., Via, Laura E., Barry III, Clifton E., Sher, Alan

“…Active tuberculosis has been linked to excessive type I interferon induction whereas interleukin-1 may have protective effects; here it is shown that…”
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Voxel-based meta-analysis of regional white-matter volume differences in autism spectrum disorder versus healthy controls by Radua, J, Via, E, Catani, M, Mataix-Cols, D

“…We conducted a meta-analysis of voxel-based morphometry (VBM) studies in autism spectrum disorder (ASD) to clarify the changes in regional white-matter volume…”
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Common and distinct patterns of grey-matter volume alteration in major depression and bipolar disorder: evidence from voxel-based meta-analysis by Wise, T, Radua, J, Via, E, Cardoner, N, Abe, O, Adams, T M, Amico, F, Cheng, Y, Cole, J H, de Azevedo Marques Périco, C, Dickstein, D P, Farrow, T F D, Frodl, T, Wagner, G, Gotlib, I H, Gruber, O, Ham, B J, Job, D E, Kempton, M J, Kim, M J, Koolschijn, P C M P, Malhi, G S, Mataix-Cols, D, McIntosh, A M, Nugent, A C, O'Brien, J T, Pezzoli, S, Phillips, M L, Sachdev, P S, Salvadore, G, Selvaraj, S, Stanfield, A C, Thomas, A J, van Tol, M J, van der Wee, N J A, Veltman, D J, Young, A H, Fu, C H, Cleare, A J, Arnone, D

“…Finding robust brain substrates of mood disorders is an important target for research. The degree to which major depression (MDD) and bipolar disorder (BD) are…”
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Microenvironments in tuberculous granulomas are delineated by distinct populations of macrophage subsets and expression of nitric oxide synthase and arginase isoforms by Mattila, Joshua T, Ojo, Olabisi O, Kepka-Lenhart, Diane, Marino, Simeone, Kim, Jin Hee, Eum, Seok Yong, Via, Laura E, Barry, 3rd, Clifton E, Klein, Edwin, Kirschner, Denise E, Morris, Jr, Sidney M, Lin, Philana Ling, Flynn, Joanne L

“…Macrophages in granulomas are both antimycobacterial effector and host cell for Mycobacterium tuberculosis, yet basic aspects of macrophage diversity and…”
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Anti-vascular endothelial growth factor treatment normalizes tuberculosis granuloma vasculature and improves small molecule delivery by Datta, Meenal, Via, Laura E., Kamoun, Walid S., Liu, Chong, Chen, Wei, Seano, Giorgio, Weiner, Danielle M., Schimel, Daniel, England, Kathleen, Martin, John D., Gao, Xing, Xu, Lei, Barry, Clifton E., Jain, Rakesh K.

“…Tuberculosis (TB) causes almost 2 million deaths annually, and an increasing number of patients are resistant to existing therapies. Patients who have TB…”
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Linezolid for Treatment of Chronic Extensively Drug-Resistant Tuberculosis by Lee, Myungsun, Lee, Jongseok, Carroll, Matthew W, Choi, Hongjo, Min, Seonyeong, Song, Taeksun, Via, Laura E, Goldfeder, Lisa C, Kang, Eunhwa, Jin, Boyoung, Park, Hyeeun, Kwak, Hyunkyung, Kim, Hyunchul, Jeon, Han-Seung, Jeong, Ina, Joh, Joon Sung, Chen, Ray Y, Olivier, Kenneth N, Shaw, Pamela A, Follmann, Dean, Song, Sun Dae, Lee, Jong-Koo, Lee, Dukhyoung, Kim, Cheon Tae, Dartois, Veronique, Park, Seung-Kyu, Cho, Sang-Nae, Barry, Clifton E

“…There are limited therapeutic options for extensively drug-resistant tuberculosis. In this study from South Korea, linezolid was shown to have some activity in…”
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Plasticity of the Mycobacterium tuberculosis respiratory chain and its impact on tuberculosis drug development by Beites, Tiago, O’Brien, Kathryn, Tiwari, Divya, Engelhart, Curtis A., Walters, Shaun, Andrews, Jenna, Yang, Hee-Jeong, Sutphen, Michelle L., Weiner, Danielle M., Dayao, Emmanuel K., Zimmerman, Matthew, Prideaux, Brendan, Desai, Prashant V., Masquelin, Thierry, Via, Laura E., Dartois, Véronique, Boshoff, Helena I., Barry, Clifton E., Ehrt, Sabine, Schnappinger, Dirk

“…The viability of Mycobacterium tuberculosis ( Mtb ) depends on energy generated by its respiratory chain. Cytochrome bc1-aa3 oxidase and type-2 NADH…”
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High-Sensitivity MALDI-MRM-MS Imaging of Moxifloxacin Distribution in Tuberculosis-Infected Rabbit Lungs and Granulomatous Lesions by Prideaux, Brendan, Dartois, Véronique, Staab, Dieter, Weiner, Danielle M, Goh, Anne, Via, Laura E, Barry, Clifton E, Stoeckli, Markus

“…MALDI-MSI is a powerful technology for localizing drug and metabolite distributions in biological tissues. To enhance our understanding of tuberculosis (TB)…”
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Storage lipid studies in tuberculosis reveal that foam cell biogenesis is disease-specific by Guerrini, Valentina, Prideaux, Brendan, Blanc, Landry, Bruiners, Natalie, Arrigucci, Riccardo, Singh, Sukhwinder, Ho-Liang, Hsin Pin, Salamon, Hugh, Chen, Pei-Yu, Lakehal, Karim, Subbian, Selvakumar, O'Brien, Paul, Via, Laura E, Barry, 3rd, Clifton E, Dartois, Véronique, Gennaro, Maria Laura

“…Foam cells are lipid-laden macrophages that contribute to the inflammation and tissue damage associated with many chronic inflammatory disorders. Although foam…”
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The within-host population dynamics of Mycobacterium tuberculosis vary with treatment efficacy by Trauner, Andrej, Liu, Qingyun, Via, Laura E, Liu, Xin, Ruan, Xianglin, Liang, Lili, Shi, Huimin, Chen, Ying, Wang, Ziling, Liang, Ruixia, Zhang, Wei, Wei, Wang, Gao, Jingcai, Sun, Gang, Brites, Daniela, England, Kathleen, Zhang, Guolong, Gagneux, Sebastien, Barry, 3rd, Clifton E, Gao, Qian

“…Combination therapy is one of the most effective tools for limiting the emergence of drug resistance in pathogens. Despite the widespread adoption of…”
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Neutrophils are the predominant infected phagocytic cells in the airways of patients with active pulmonary TB by Eum, Seok-Yong, Kong, Ji-Hye, Hong, Min-Sun, Lee, Ye-Jin, Kim, Jin-Hee, Hwang, Soo-Hee, Cho, Sang-Nae, Via, Laura E, Barry, 3rd, Clifton E

“…The exact role of neutrophils in the pathogenesis of TB is poorly understood. Recent evidence suggests that neutrophils are not simply scavenging phagocytes in…”
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Pharmacokinetic Evaluation of the Penetration of Antituberculosis Agents in Rabbit Pulmonary Lesions by KJELLSSON, Maria C, VIA, Laura E, GOH, Anne, WEINER, Danielle, KANG MIN LOW, KERN, Steven, PILLAI, Goonaseelan, BARRY, Clifton E, DARTOIS, Véronique

“…OA  Classifications Services AAC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Evaluation of a Rapid Molecular Drug-Susceptibility Test for Tuberculosis by Xie, Yingda L, Chakravorty, Soumitesh, Armstrong, Derek T, Hall, Sandra L, Via, Laura E, Song, Taeksun, Yuan, Xing, Mo, Xiaoying, Zhu, Hong, Xu, Peng, Gao, Qian, Lee, Myungsun, Lee, Jongseok, Smith, Laura E, Chen, Ray Y, Joh, Joon Sung, Cho, YoungSoo, Liu, Xin, Ruan, Xianglin, Liang, Lili, Dharan, Nila, Cho, Sang-Nae, Barry, Clifton E, Ellner, Jerrold J, Dorman, Susan E, Alland, David

“…Increasing drug resistance in Mycobacterium tuberculosis complicates the management of tuberculosis. Development of a point-of-care test to determine drug…”
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The wide utility of rabbits as models of human diseases by Esteves, Pedro J., Abrantes, Joana, Baldauf, Hanna-Mari, BenMohamed, Lbachir, Chen, Yuxing, Christensen, Neil, González-Gallego, Javier, Giacani, Lorenzo, Hu, Jiafen, Kaplan, Gilla, Keppler, Oliver T., Knight, Katherine L., Kong, Xiang-Peng, Lanning, Dennis K., Le Pendu, Jacques, de Matos, Ana Lemos, Liu, Jia, Liu, Shuying, Lopes, Ana M., Lu, Shan, Lukehart, Sheila, Manabe, Yukari C., Neves, Fabiana, McFadden, Grant, Pan, Ruimin, Peng, Xuwen, de Sousa-Pereira, Patricia, Pinheiro, Ana, Rahman, Masmudur, Ruvoën-Clouet, Natalie, Subbian, Selvakumar, Tuñón, Maria Jesús, van der Loo, Wessel, Vaine, Michael, Via, Laura E., Wang, Shixia, Mage, Rose

“…Studies using the European rabbit Oryctolagus cuniculus contributed to elucidating numerous fundamental aspects of antibody structure and diversification…”
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Automated quantitative assay of fibrosis characteristics in tuberculosis granulomas by Song, Li, Zhang, Ding, Wang, Hankun, Xia, Xuan, Huang, Weifeng, Gonzales, Jacqueline, Via, Laura E, Wang, Decheng

“…Granulomas, the pathological hallmark of ( ) infection, are formed by different cell populations. Across various stages of tuberculosis conditions, most…”
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Mathematical model of oxygen, nutrient, and drug transport in tuberculosis granulomas by Datta, Meenal, Kennedy, McCarthy, Siri, Saeed, Via, Laura E, Baish, James W, Xu, Lei, Dartois, Véronique, Barry, 3rd, Clifton E, Jain, Rakesh K

“…Physiological abnormalities in pulmonary granulomas-pathological hallmarks of tuberculosis (TB)-compromise the transport of oxygen, nutrients, and drugs. In…”
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Tuberculous Granulomas Are Hypoxic in Guinea Pigs, Rabbits, and Nonhuman Primates by Via, Laura E, Lin, P. Ling, Ray, Sonja M, Carrillo, Jose, Allen, Shannon Sedberry, Eum, Seok Yong, Taylor, Kimberly, Klein, Edwin, Manjunatha, Ujjini, Gonzales, Jacqueline, Lee, Eun Gae, Park, Seung Kyu, Raleigh, James A, Cho, Sang Nae, McMurray, David N, Flynn, JoAnne L, Barry, Clifton E. III

“…Understanding the physical characteristics of the local microenvironment in which Mycobacterium tuberculosis resides is an important goal that may allow the…”
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