Search Results - "Vi, Nancy"
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A gene co-expression network in whole blood of schizophrenia patients is independent of antipsychotic-use and enriched for brain-expressed genes
Published in PloS one (27-06-2012)“…Despite large-scale genome-wide association studies (GWAS), the underlying genes for schizophrenia are largely unknown. Additional approaches are therefore…”
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Integrative gene–tissue microarray-based approach for identification of human disease biomarkers: application to amyotrophic lateral sclerosis
Published in Human molecular genetics (15-08-2010)“…Advances in genomics and proteomics permit rapid identification of disease-relevant genes and proteins. Challenges include biological differences between…”
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Novel Cell and Tissue Acquisition System (CTAS): microdissection of live and frozen brain tissues
Published in PloS one (24-07-2012)“…We developed a novel, highly accurate, capillary based vacuum-assisted microdissection device CTAS-Cell and Tissue Acquisition System, for efficient isolation…”
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Puromycin-sensitive aminopeptidase (PSA/NPEPPS) impedes development of neuropathology in hPSA/TAUP301L double-transgenic mice
Published in Human molecular genetics (01-05-2011)Get full text
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Puromycin-sensitive aminopeptidase (PSA/NPEPPS) impedes development of neuropathology in hPSA/TAU(P301L) double-transgenic mice
Published in Human molecular genetics (01-05-2011)“…Accumulation of neurotoxic hyperphosphorylated TAU protein is a major pathological hallmark of Alzheimer disease and other neurodegenerative dementias…”
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Novel Cell and Tissue Acquisition System
Published in PloS one (24-07-2012)“…We developed a novel, highly accurate, capillary based vacuum-assisted microdissection device CTAS - Cell and Tissue Acquisition System, for efficient…”
Get full text
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Predicting epilepsy with peripheral blood transcriptome biomarkers during early latent period
Published in The FASEB journal (01-04-2010)“…Status epilepticus (SE) is a common cause of hippocampal neurodegeneration and synaptic reorganization that may or may not lead to the development of epilepsy…”
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CTAS: a novel low‐cost capillary‐based cell and tissue acquisition system
Published in The FASEB journal (01-04-2010)“…Heterogeneity in tissue samples and cell cultures is a limiting factor that hinders sound cell‐specific molecular studies of disease and health both for gene…”
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Puromycin-sensitive aminopeptidase (PSA/NPEPPS) impedes development of neuropathology in hPSA/TAU super(P301L) double-transgenic mice
Published in Human molecular genetics (01-05-2011)“…Accumulation of neurotoxic hyperphosphorylated TAU protein is a major pathological hallmark of Alzheimer disease and other neurodegenerative dementias…”
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Puromycin Sensitive Aminopeptidase (PSA/NPEPPS) has neuroprotective effect in the mouse model of TAU induced neurodegeneration
Published in The FASEB journal (01-04-2010)“…Previously we identified PSA as a novel modifier of TAU‐induced neurodegeneration with effects via direct proteolysis of TAU protein. To investigate PSA's…”
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P3‐205: Effect of puromycin sensitive aminopeptidase overexpression on TAU protein metabolism in vivo
Published in Alzheimer's & dementia (01-07-2009)Get full text
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Effect of puromycin sensitive aminopeptidase overexpression on TAU protein metabolism in vivo
Published in Alzheimer's & dementia (01-07-2009)Get full text
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