Search Results - "Vezina, P."

Sensitization of midbrain dopamine neuron reactivity and the self-administration of psychomotor stimulant drugs by Vezina, Paul

“…Psychostimulant drugs like amphetamine are readily self-administered by humans and laboratory animals by virtue of their actions on dopamine (DA) neurons in…”
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Transient co-expression for fast and high-yield production of antibodies with human-like N-glycans in plants by Vézina, Louis-P, Faye, Loïc, Lerouge, Patrice, D'Aoust, Marc-André, Marquet-Blouin, Estelle, Burel, Carole, Lavoie, Pierre-Olivier, Bardor, Muriel, Gomord, Véronique

“…Plant-based transient expression is potentially the most rapid and cost-efficient system for the production of recombinant pharmaceutical proteins, but safety…”
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Exposure to nicotine and sensitization of nicotine-induced behaviors by Vezina, P., McGehee, D.S., Green, W.N.

“…Evidence for an important link between sensitization of midbrain dopamine (DA) neuron reactivity and enhanced self-administration of amphetamine and cocaine…”
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Unpredictable saccharin reinforcement enhances locomotor responding to amphetamine by Singer, B.F., Scott-Railton, J., Vezina, P.

“…► Drug-naïve rats were trained to self-administer saccharin. ► Saccharin reinforcement was either predictable or unpredictable. ► Unpredictable saccharin…”
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D1 dopamine receptor activation is necessary for the induction of sensitization by amphetamine in the ventral tegmental area by Vezina, P

“…Repeated intermittent exposure to amphetamine produces long-term enhancements in the ability of this drug to produce locomotion and increase extracellular…”
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Inhibiting cyclin-dependent kinase 5 in the nucleus accumbens enhances the expression of amphetamine-induced locomotor conditioning by Singer, B.F., Forneris, J., Vezina, P.

“…•The formation of drug-context associations contributes to addiction.•Inhibiting NAcc Cdk5 enhances the expression of amphetamine-induced conditioning.•This…”
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Preclinical and clinical development of plant-made virus-like particle vaccine against avian H5N1 influenza by Landry, Nathalie, Ward, Brian J, Trépanier, Sonia, Montomoli, Emanuele, Dargis, Michèle, Lapini, Giulia, Vézina, Louis-P

“…The recent swine H1N1 influenza outbreak demonstrated that egg-based vaccine manufacturing has an Achille's heel: its inability to provide a large number of…”
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Transient viral-mediated overexpression of a-calcium/calmodulin-dependent protein kinase II in the nucleus accumbens shell leads to long-lasting functional upregulation of a-amino-3-hydroxyl-5-methyl-4-isoxazole-propionate receptors: dopamine type-1 receptor and protein kinase A dependence by Singer, B F, Loweth, JA, Neve, R L, Vezina, P

“…AbstractCalcium-calmodulin-dependent protein kinase II (CaMKII) activity is necessary for the long-lasting expression of locomotor sensitization and enhanced…”
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Transient viral-mediated overexpression of α-calcium/calmodulin-dependent protein kinase II in the nucleus accumbens shell leads to long-lasting functional upregulation of α-amino-3-hydroxyl-5-methyl-4-isoxazole-propionate receptors: dopamine type-1 receptor and protein kinase A dependence by Singer, B. F., Loweth, J. A., Neve, R. L., Vezina, P.

“…Calcium/calmodulin‐dependent protein kinase II (CaMKII) activity is necessary for the long‐lasting expression of locomotor sensitization and enhanced…”
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S7 LONG-LASTING CHANGES IN DOPAMINE AND GLUTAMATE TRANSMISSION AND DRUG TAKING by Vezina, P

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The production of hemagglutinin-based virus-like particles in plants: a rapid, efficient and safe response to pandemic influenza by D'Aoust, Marc-André, Couture, Manon M-J, Charland, Nathalie, Trépanier, Sonia, Landry, Nathalie, Ors, Frédéric, Vézina, Louis-P

“…During the last decade, the spectre of an influenza pandemic of avian origin has led to a revision of national and global pandemic preparedness plans and has…”
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Human antibody response to N-glycans present on plant-made influenza virus-like particle (VLP) vaccines by Ward, Brian J, Landry, Nathalie, Trépanier, Sonia, Mercier, Geneviève, Dargis, Michèle, Couture, Manon, D’Aoust, Marc-André, Vézina, Louis-P

“…Abstract Background Plant-made biotherapeutics are gathering momentum and some plant glycoproteins are allergens. Glycans with core β1-2xylose and α1,3fucose…”
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Induction of locomotor sensitization by amphetamine requires the activation of NMDA receptors in the rat ventral tegmental area by Vezina, P, Queen, A L

“…The activation of NMDA receptors in the rat ventral tegmental area has been proposed to be necessary for the induction of locomotor sensitization by…”
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Radiofrequency of the soft palate for sleep-disordered breathing: A 6-year follow-up study by De Kermadec, H, Blumen, M.-B, Engalenc, D, Vezina, J.-P, Chabolle, F

“…Abstract Objective To determine the long-term (> 3 years) outcome of patients suffering from simple snoring or non-severe obstructive sleep apnea syndrome…”
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MsCYS1, a developmentally-regulated cystatin from alfalfa by Rivard, Daniel, Girard, Cécile, Anguenot, Raphaël, Vézina, Louis-P., Trépanier, Sonia, Michaud, Dominique

“…Several roles have been attributed to cystatins in plants, ranging from the regulation of host [endogenous] cysteine proteases to the inhibition of herbivorous…”
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Locomotor response to novelty predicts a rat's propensity to self-administer nicotine by SUTO, Nobuyoshi, AUSTIN, Jennifer D, VEZINA, Paul

“…A positive correlation between responding to novelty and propensity to subsequently self-administer a drug has been reported for opioids and psychomotor…”
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Amphetamine administered to the ventral tegmental area sensitizes rats to the locomotor effects of nucleus accumbens amphetamine by Perugini, M, Vezina, P

“…This experiment investigated whether pre-exposure to injections of amphetamine into the ventral tegmental area (VTA) sensitizes the locomotor response to a…”
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Previous exposure to amphetamine increases incentive to obtain the drug: long-lasting effects revealed by the progressive ratio schedule by Lorrain, D.S, Arnold, G.M, Vezina, P

“…The present experiment tested whether previous exposure to amphetamine would enhance rats’ predisposition to self-administer a high dose of the drug under…”
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Plant‐produced Der p 2‐bearing bioparticles activate Th1/Treg‐related activation patterns in dendritic cells irrespective of the allergic background by Busold, Stefanie, Aglas, Lorenz, Menage, Charlotte, Desgagnés, Réjean, Faye, Loïc, Fitchette, Anne‐Catherine, Jong, Esther C., Martel, Caroline, Stigler, Maria, Catala‐Stordeur, Virginie, Tropper, Guy, Auger, Lydia, Morel, Bertrand, Versteeg, Serge A., Vézina, Louis‐P, Gomord, Véronique, Layhadi, Janice A., Shamji, Mohamed, Geijtenbeek, Teunis B. H., Ree, Ronald

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Cerebrospinal fluid otorrhoea: a rare presentation of Langerhans' cell histiocytosis of the temporal bone by Vezina, J-P, Audet, N, Fradet, G

“…To report a case of Langerhans cell histiocytosis of the temporal bone presenting with cerebrospinal fluid fistula. A Caucasian woman presented to a tertiary…”
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