Search Results - "Veyrat‐Durebex, C"
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Lipidomics Reveals Cerebrospinal-Fluid Signatures of ALS
Published in Scientific reports (15-12-2017)“…Amyotrophic lateral sclerosis (ALS), the commonest adult-onset motor neuron disorder, is characterized by a survival span of only 2–5 years after onset…”
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A ferroptosis–based panel of prognostic biomarkers for Amyotrophic Lateral Sclerosis
Published in Scientific reports (27-02-2019)“…Accurate patient stratification into prognostic categories and targeting Amyotrophic Lateral Sclerosis (ALS)-associated pathways may pave the way for promising…”
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3
Chronic mTOR inhibition by rapamycin induces muscle insulin resistance despite weight loss in rats
Published in British journal of pharmacology (01-04-2012)“…BACKGROUND AND PURPOSE mTOR inhibitors are currently used as immunosuppressants in transplanted patients and as promising anti‐cancer agents. However,…”
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Biological follow-up in amyotrophic lateral sclerosis: decrease in creatinine levels and increase in ferritin levels predict poor prognosis
Published in European journal of neurology (01-10-2015)“…Background and purpose Amyotrophic lateral sclerosis (ALS) is a fatal disorder of the motor neuron system, with a median survival of 2 to 4 years and a wide…”
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New case of bilateral pheochromocytomas involving the homozygous TMEM127 mutation
Published in Clinical genetics (01-08-2018)Get full text
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Deficiency in the NADPH oxidase 4 predisposes towards diet-induced obesity
Published in International Journal of Obesity (01-12-2012)“…OBJECTIVE: NADPH oxidase 4 (NOX4) is a reactive oxygen species (ROS) producing NADPH oxidase that regulates redox homeostasis in diverse insulin-sensitive cell…”
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Biomarkers in amyotrophic lateral sclerosis: combining metabolomic and clinical parameters to define disease progression
Published in European journal of neurology (01-02-2016)“…Background and purpose The objectives of this study were to define the metabolomic profile of cerebrospinal fluid in amyotrophic lateral sclerosis (ALS)…”
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A Multiplatform Metabolomics Approach to Characterize Plasma Levels of Phenylalanine and Tyrosine in Phenylketonuria
Published in JIMD Reports, Volume 32 (01-01-2017)“…Background: Different pathophysiological mechanisms have been described in phenylketonuria (PKU) but the indirect metabolic consequences of metabolic disorders…”
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Validation of plasma amino acid profile using UHPLC-mass spectrometer (QDa) as a screening method in a metabolic disorders reference centre: Performance and accreditation concerns
Published in Clinical biochemistry (01-06-2021)“…Amino acid (AA) analysis in plasma is essential for diagnosis and monitoring of inborn errors of metabolism (IEM). The efficacy of patient management is…”
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Behavioral, Hormonal, Inflammatory, and Metabolic Effects Associated with FGF21-Pathway Activation in an ALS Mouse Model
Published in Neurotherapeutics (01-01-2021)“…In amyotrophic lateral sclerosis (ALS), motor neuron degeneration occurs simultaneously with systemic metabolic dysfunction and neuro-inflammation. The…”
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Regulation of the Pituitary Growth Hormone-Releasing Hormone Receptor in Ageing Male and Female LOU Rats: New Insights into Healthy Ageing
Published in Journal of neuroendocrinology (01-11-2005)“…Ageing is characterised by a decrease of somatotroph functionality, involving growth hormone‐releasing hormone receptor (GHRH‐R). The present study was…”
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Age-related changes in nociception and effect of morphine in the Lou rat
Published in European journal of pain (01-09-2000)“…Little is known about how the ageing process affects pain sensitivity and a relevant animal model is therefore required. The effect of age on pain reactivity…”
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Author Correction: A ferroptosis–based panel of prognostic biomarkers for Amyotrophic Lateral Sclerosis
Published in Scientific reports (19-02-2020)“…An amendment to this paper has been published and can be accessed via a link at the top of the paper…”
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Advances in Cellular Models to Explore the Pathophysiology of Amyotrophic Lateral Sclerosis
Published in Molecular neurobiology (01-04-2014)“…Amyotrophic lateral sclerosis (ALS), the most common adult-onset motor neuron disorder, is fatal for most patients less than 3 years from when the first…”
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The LOU/c/jall rat as an animal model of healthy aging?
Published in The journals of gerontology. Series A, Biological sciences and medical sciences (01-08-2002)“…We propose the LOU/c/jall rat as a possible model for research into aging. Physiological and behavioral data have been collected over the past 5 years, using…”
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P1035 Une exposition périnatale à une diète hyperlipidique peut altérer la tolérance au glucose à l’âge adulte, indépendamment des niveaux circulants de leptine
Published in Diabetes & metabolism (26-03-2013)“…Introduction De récentes études suggèrent que l’alimentation reçue en période périnatale peut avoir une influence prépondérante sur le métabolisme énergétique…”
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P1046 Présence d’adipocytes bruns dans le tissu adipeux blanc et son rôle dans la résistance à l’obésité et la sensibilité à l’insuline
Published in Diabetes & metabolism (26-03-2013)“…Introduction Le tissu adipeux brun (BAT), caractérisé par l’expression de la protéine découplante de type 1 (UCP1) a récemment été décrit comme métaboliquement…”
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P264 - Métabolisme des lipides et thermogenèse chez le rat Lou/C, un modèle de résistance au développement de l’obésité : implication de la protéine découplante 1 (UCP1) dans le tissu adipeux blanc
Published in Diabetes & metabolism (2011)“…Introduction De précédents travaux ont décrit le rat Lou/C, souche dérivée du Wistar, comme un modèle de résistance au développement de l’obésité avec l’âge et…”
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Dietary Self-Selection Can Compensate an Age-Related Decrease of Rat Liver 20 S Proteasome Activity Observed With Standard Diet
Published in The journals of gerontology. Series A, Biological sciences and medical sciences (01-05-1998)“…Aged Lou female rats (33 months) submitted to a self-selection regimen showed a decrease in protein intake (down to 11% of the total intake), whereas mature…”
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Age-related changes in adaptive mechanisms of macronutrient self-selection: evidence for a sexual dimorphism
Published in Mechanisms of ageing and development (15-07-1998)“…The effect of aging on patterns of food intake and nutrient selection was investigated using a longitudinal study. Male ( n=10) and female ( n=10) Wistar–Lou…”
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