Search Results - "Veverová, Kateřina"

Identification and potential clinical applications of novel autophagy/mitophagy proteins in the biofluids of Alzheimer’s disease patients by Zhang, Jianying, Wang, He-Ling, Veverová, Kateřina, Vyhnálek, Martin, Fang, Evandro Fei

“…•Elevated PINK1 and reduced TFEB in CSF and serum samples of AD patients.•Correlations were found between levels of PINK1, TFEB, and clinical indicators of…”
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Evaluation of Differential Diagnostics Potential of Uniform Data Set 2 Neuropsychology Battery Using Alzheimer’s Disease Biomarkers by Čihák, Martin, Horáková, Hana, Vyhnálek, Martin, Veverová, Kateřina, Matušková, Veronika, Laczó, Jan, Hort, Jakub, Nikolai, Tomáš

“…Abstract Objective This study aims to evaluate the efficacy of the Uniform Data Set (UDS) 2 battery in distinguishing between individuals with mild cognitive…”
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Alterations of human CSF and serum-based mitophagy biomarkers in the continuum of Alzheimer disease by Veverová, Kateřina, Laczó, Jan, Katonová, Alžběta, Horáková, Hana, Matušková, Veronika, Angelucci, Francesco, Laczó, Martina, Nedelská, Zuzana, Hort, Jakub, Wang, He-Ling, Zhang, Jianying, Shi, Liu, Fei Fang, Evandro, Vyhnálek, Martin

“…Defective mitophagy is consistently found in postmortem brain and iPSC-derived neurons from Alzheimer disease (AD) patients. However, there is a lack of…”
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Compromised autophagy and mitophagy in brain ageing and Alzheimer’s diseases by Caponio, Domenica, Veverová, Kateřina, Zhang, Shi-qi, Shi, Liu, Wong, Garry, Vyhnalek, Martin, Fang, Evandro F.

“…Alzheimer’s disease (AD) is one of the most persistent and devastating neurodegenerative disorders of old age, and is characterized clinically by an insidious…”
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Alzheimer’s Disease Severity Is Associated with an Imbalance in Serum Levels of Enzymes Regulating Plasmin Synthesis by Angelucci, Francesco, Veverova, Katerina, Katonová, Alžbeta, Piendel, Lydia, Vyhnalek, Martin, Hort, Jakub

“…Alzheimer’s disease (AD) is a central nervous system (CNS) disease characterized by loss of memory, cognitive functions, and neurodegeneration. Plasmin is an…”
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Serum PAI-1/BDNF Ratio Is Increased in Alzheimer’s Disease and Correlates with Disease Severity by Angelucci, Francesco, Veverova, Katerina, Katonová, Alžbeta, Vyhnalek, Martin, Hort, Jakub

“…We previously demonstrated that serum levels of plasminogen activator inhibitor-1 (PAI-1), which inhibits both the tissue plasminogen activator (tPA) and…”
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Moderating effect of cognitive reserve on brain integrity and cognitive performance by Nelson, Monica E., Veal, Britney M., Andel, Ross, Martinkova, Julie, Veverova, Katerina, Horakova, Hana, Nedelska, Zuzana, Laczó, Jan, Vyhnalek, Martin, Hort, Jakub

“…Background Dementia syndrome is one of the most devastating conditions in older adults. As treatments to stop neurodegeneration become available, accurate and…”
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Mild behavioral impairment in early Alzheimer's disease and its association with APOE and BDNF risk genetic polymorphisms by Matuskova, Veronika, Veverova, Katerina, Jester, Dylan J, Matoska, Vaclav, Ismail, Zahinoor, Sheardova, Katerina, Horakova, Hana, Cerman, Jiri, Laczó, Jan, Andel, Ross, Hort, Jakub, Vyhnalek, Martin

“…Mild behavioral impairment (MBI) has been commonly reported in early Alzheimer's disease (AD) but rarely using biomarker-defined samples. It is also unclear…”
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CSF neurogranin levels as a biomarker in Alzheimer's disease and frontotemporal lobar degeneration: a cross-sectional analysis by Jurasova, Vanesa, Andel, Ross, Katonova, Alzbeta, Veverova, Katerina, Zuntychova, Terezie, Horakova, Hana, Vyhnalek, Martin, Kolarova, Tereza, Matoska, Vaclav, Blennow, Kaj, Hort, Jakub

“…There is initial evidence suggesting that biomarker neurogranin (Ng) may distinguish Alzheimer's disease (AD) from other neurodegenerative diseases. Therefore,…”
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Plasminogen activator inhibitor‐1 serum levels in frontotemporal lobar degeneration by Angelucci, Francesco, Veverova, Katerina, Katonová, Alžbeta, Vyhnalek, Martin, Hort, Jakub

“…Plasminogen activator inhibitor‐1 (PAI‐1) impedes brain plasmin synthesis. Reduced plasmin activity facilitates cumulation of amyloid beta (Aβ) in Alzheimer's…”
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Specific memory binding indexes and their potential to discriminate between Alzheimer´s disease biomarker‐positive and biomarker‐negative older adults with amnestic mild cognitive impairment by Horakova, Hana, Mazancova, Adela Fendrych, Matuskova, Veronika, Veverova, Katerina, Laczó, Jan, Hort, Jakub, Vyhnalek, Martin

“…Background The Memory Binding Test (MBT) and Face‐Name Associative Memory Exam (FNAME‐12) are challenging tests based on relational memory binding paradigm…”
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Differentiation of clinically diagnosed patients with aMCI and dementia from cognitively unimpaired older adults using plasma and serum p‐tau 181 and NfL by Jurasova, Vanesa, Veverova, Katerina, Angelucci, Francesco, Katonova, Alzbeta, Vyhnalek, Martin, Andel, Ross, Hort, Jakub

“…Background Blood‐based biomarkers give the possibility of having a less invasive, more acceptable to patients, and cost‐ and time‐efficient screening tool…”
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The molar ratio between PAI‐1 and BDNF is increased in Alzheimer’s disease patients with full dementia and negatively correlates with MMSE score by Angelucci, Francesco, Veverova, Katerina, Katonova, Alzbeta, Jurasova, Vanesa, Vyhnalek, Martin, Andel, Ross, Hort, Jakub, Sheardova, Katerina

“…Background In a previous study, we demonstrated that the enzyme plasminogen activator inhibitor‐1 (PAI‐1), which inhibits plasmin synthesis in the central…”
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Levels of Mitophagy Biomarkers Differ Between Individuals With Alzheimer’s disease and Frontotemporal Lobar Degeneration by Katonova, Alzbeta, Veverova, Katerina, Horakova, Hana, Angelucci, Francesco, Laczó, Jan, Hort, Jakub, Shi, Liu, Fang, Evandro Fei, Vyhnalek, Martin

“…Background Reduced removal of dysfunctional mitochondria has been implicated in the pathogenesis of many neurodegenerative diseases, including Alzheimer’s…”
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Mitophagy biomarkers are changed in the continuum of Alzheimer’s disease by Veverova, Katerina, Katonova, Alzbeta, Horakova, Hana, Angelucci, Francesco, Laczó, Jan, Hort, Jakub, Shi, Liu, Fang, Evandro Fei, Vyhnalek, Martin

“…Background Autophagy is a cellular self “garbage clearance ”system through which cells eliminate and recycle dysfunctional cytoplasmatic components, such as…”
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Plasma protein profiling reveals novel specific biomarkers reflecting the multifactorial nature of Alzheimer´s disease continuum by Bellomo, Giovanni, in ’t Veld, Sjors G.J.G., Doecke, James D, Quesada, Carlos, Vermunt, Lisa, Alcolea, Daniel, Halbgebauer, Steffen, Mattsson‐Carlgren, Niklas, Veverova, Katerina, Boonkamp, Lynn, Hok‐A‐Hin, Yanaika S., Fowler, Christopher J, Fortea, Juan, Gaetani, Lorenzo, Toja, Andrea, Pijnenburg, Yolande A.L., Lemstra, Afina W., van der Flier, Wiesje M., Hort, Jakub, Otto, Markus, Hansson, Oskar, Masters, Colin L, Lleó, Alberto, Parnetti, Lucilla, Teunissen, Charlotte E., del Campo, Marta

“…Background Plasma‐based biomarkers able to depict the molecular diversity associated to Alzheimer´s disease (AD) are needed to better track disease progression…”
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Plasma pTau181 and biomarker combinations to identify Alzheimer´s disease at any stage along the AD continuum compared with both controls and non‐AD dementia by Doecke, James D, Bellomo, Giovanni, Vermunt, Lisa, Alcolea, Daniel, Halbgebauer, Steffen, in ’t Veld, Sjors G.J.G., Mattsson‐Carlgren, Niklas, Veverova, Katerina, Fowler, Christopher J, Boonkamp, Lynn, Koel‐Simmerlink, Marleen, Hussainali, Zulaiga, Ruiters, Daimy N., Gaetani, Lorenzo, Toja, Andrea, Fortea, Juan, Pijnenburg, Yolande A.L., Lemstra, Afina W., van der Flier, Wiesje M., Hort, Jakub, Otto, Markus, Hansson, Oskar, Parnetti, Lucilla, Masters, Colin L, Lleó, Alberto, del Campo, Marta, Teunissen, Charlotte E.

“…Background The latest generation of plasma biomarkers (phosphorylated Tau181 (pTau181), Glial fibrillary acidic protein (GFAP), Neurofilament light (NFL) and…”
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Meeting Summary of The NYO3 5th NO-Age/AD Meeting and the 1st Norway–UK Joint Meeting on Aging and Dementia: Recent Progress on the Mechanisms and Interventional Strategies by Wang, He-Ling, Siow, Richard, Schmauck-Medina, Tomas, Zhang, Jianying, Sandset, Per Morten, Filshie, Clare, Lund, Øystein, Partridge, Linda, Bergersen, Linda Hildegard, Juel Rasmussen, Lene, Palikaras, Konstantinos, Sotiropoulos, Ioannis, Storm-Mathisen, Jon, Rubinsztein, David C, Spillantini, Maria Grazia, De Zeeuw, Chris I, Watne, Leiv Otto, Vyhnalek, Martin, Veverova, Katerina, Liang, Kristina Xiao, Tavernarakis, Nektarios, Bohr, Vilhelm A, Yokote, Koutaro, Saarela, Janna, Nilsen, Hilde, Gonos, Efstathios S, Scheibye-Knudsen, Morten, Chen, Guobing, Kato, Hisaya, Selbæk, Geir, Fladby, Tormod, Nilsson, Per, Simonsen, Anne, Aarsland, Dag, Lautrup, Sofie, Ottersen, Ole Petter, Cox, Lynne S, Fang, Evandro F

“…Abstract Unhealthy aging poses a global challenge with profound healthcare and socioeconomic implications. Slowing down the aging process offers a promising…”
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