Search Results - "Vetrugno, Vito"

Trapping Prion Protein in the Endoplasmic Reticulum Impairs PrPC Maturation and Prevents PrPSc Accumulation by Cardinale, Alessio, Filesi, Ilaria, Vetrugno, Vito, Pocchiari, Maurizio, Sy, Man-Sun, Biocca, Silvia

“…The conversion of the normal cellular prion protein (PrPC) into the abnormal scrapie isoform (PrPSc) is a key feature of prion diseases. The pathogenic…”
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Accumulation and aberrant composition of cholesteryl esters in Scrapie-infected N2a cells and C57BL/6 mouse brains by Vascellari, Sarah, Banni, Sebastiano, Vacca, Claudia, Vetrugno, Vito, Cardone, Franco, Di Bari, Michele A, La Colla, Paolo, Pani, Alessandra

“…Cholesterol changes have been described in prion-cell models and in experimental rodent scrapie; yet, the pattern of this association is still controversial…”
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Transmission of sporadic Creutzfeldt-Jakob disease by blood transfusion: risk factor or possible biases by Puopolo, Maria, Ladogana, Anna, Vetrugno, Vito, Pocchiari, Maurizio

“…BACKGROUND: The occurrence of transfusion transmissions of variant Creutzfeldt‐Jakob disease (CJD) cases has reawakened attention to the possible similar risk…”
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Scrapie infectivity is quickly cleared in tissues of orally-infected farmed fish by Ingrosso, Loredana, Novoa, Beatriz, Valle, Andrea Z Dalla, Cardone, Franco, Aranguren, Raquel, Sbriccoli, Marco, Bevivino, Simona, Iriti, Marcello, Liu, Quanguo, Vetrugno, Vito, Lu, Mei, Faoro, Franco, Ciappellano, Salvatore, Figueras, Antonio, Pocchiari, Maurizio

“…Scrapie and bovine spongiform encephalopathy (BSE) belongs to the group of animal transmissible spongiform encephalopathy (TSE). BSE epidemic in the UK and…”
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In reply by Puopolo, Maria, Ladogana, Anna, Vetrugno, Vito, Pocchiari, Maurizio

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In reply by Puopolo, Maria, Ladogana, Anna, Vetrugno, Vito, Pocchiari, Maurizio

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In reply by Puopolo, Maria, Ladogana, Anna, Vetrugno, Vito, Pocchiari, Maurizio

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Safety of milk and milk derivatives in relation to BSE: the lactoferrin example by Vetrugno, Vito

“…Bovine Spongiform Encephalopathy (BSE) belongs to Transmissible Spongiform Encephalopathies (TSEs) or Prion diseases. BSE is a feed borne infection of cattle…”
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Management of notifications of donors with Creutzfeldt-Jakob disease (post-donation information) by Calizzani, Gabriele, Vaglio, Stefania, Vetrugno, Vito, Delbò, Marisa, Pani, Luca, Grazzini, Giuliano

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Oral pravastatin prolongs survival time of scrapie-infected mice by Vetrugno, Vito, Di Bari, Michele Angelo, Nonno, Romolo, Puopolo, Maria, D'Agostino, Claudia, Pirisinu, Laura, Pocchiari, Maurizio, Agrimi, Umberto

“…Statins are potent inhibitors of HMG–CoA (3-hydroxy-3-methylglutaryl coenzyme A) reductase in the cholesterol-biosynthesis pathway. They are either lipophilic…”
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KDEL-tagged anti-prion intrabodies impair PrP lysosomal degradation and inhibit scrapie infectivity by Vetrugno, Vito, Cardinale, Alessio, Filesi, Ilaria, Mattei, Sonia, Sy, Man-Sun, Pocchiari, Maurizio, Biocca, Silvia

“…Transmissible spongiform encephalopathy or prion diseases are fatal neurodegenerative disorders characterized by the conversion of the cellular prion protein…”
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Regulation of intrinsic prion protein by growth factors and tnf-α: the role of intracellular reactive oxygen species by Sauer, Heinrich, Wefer, Katrin, Vetrugno, Vito, Pocchiari, Maurizio, Gissel, Cornelia, Sachinidis, Agapios, Hescheler, Jürgen, Wartenberg, Maria

“…Function and regulation of the intrinsic prion protein (PrP c) are largely unknown. In the present study the regulation of PrP c expression by growth factors…”
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Molecular diagnostics of transmissible spongiform encephalopathies by Ingrosso, Loredana, Vetrugno, Vito, Cardone, Franco, Pocchiari, Maurizio

“…Clinical criteria for the diagnosis of sporadic, iatrogenic and variant Creutzfeldt–Jakob diseases are now available and show an excellent sensitivity and…”
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Expression of wild-type and V210I mutant prion protein in human neuroblastoma cells by Vetrugno, Vito, Malchow, Michaela, Liu, Quan-guo, Marziali, Giovanna, Battistini, Angela, Pocchiari, Maurizio

“…The conversion of the host-encoded prion protein (PrPc) into the insoluble, protease-resistant isoform (PrPsc) is the main pathogenic mechanism of…”
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