Search Results - "Vestal, D. J."

Inhibition of VSV and EMCV replication by the interferon-induced GTPase, mGBP-2 : differential requirement for wild-type GTP binding domain by CARTER, C. C, GORBACHEVA, V. Y, VESTAL, D. J

“…Interferons (IFNs) exert their anti-viral activities through the induction of anti-viral proteins. One member of the guanylate binding protein (GBP) family of…”
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Targeted disruption of the PU.1 gene results in multiple hematopoietic abnormalities by McKercher, S. R., Torbett, B. E., Anderson, K. L., Henkel, G. W., Vestal, D. J., Baribault, H., Klemsz, M., Feeney, A. J., Wu, G. E., Paige, C. J., Maki, R. A.

“…PU.1 is a member of the ets family of transcription factors and is expressed exclusively in cells of the hematopoietic lineage. Mice homozygous for a…”
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Glycosyl Phosphatidylinositol-Anchored T-Cadherin Mediates Calcium-Dependent, Homophilic Cell Adhesion by Vestal, Deborah J., Ranscht, Barbara

“…Cadherins are a family of cell adhesion molecules that exhibit calcium-dependent, homophilic binding. Their function depends on both an HisAlaVal sequence in…”
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Different subcellular localizations for the related interferon-induced GTPases, MuGBP-1 and MuGBP-2: implications for different functions? by Vestal, D J, Gorbacheva, V Y, Sen, G C

“…The guanylate-binding proteins (GBPs) are a family of 65-67-kDa proteins induced by both type I and type II interferons (IFN). Members of the GBP family of…”
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Purification and functional characterization of integrin alpha v beta 5. An adhesion receptor for vitronectin by Smith, J W, Vestal, D J, Irwin, S V, Burke, T A, Cheresh, D A

“…We have purified a novel member of the integrin gene family from placenta that serves as a vitronectin receptor. This integrin is composed of the alpha v…”
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Prenylation of an interferon-gamma-induced GTP-binding protein: the human guanylate binding protein, huGBP1 by Nantais, David E., Schwemmle, Martin, Stickney, John T., Vestal, Deborah J., Buss, Janice E.

“…Interferons (IFN) and lipopolysaccharide (LPS) cause multiple changes in isoprenoid‐modified proteins in murine macrophages, the most dramatic being the…”
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The guanylate-binding proteins (GBPs): proinflammatory cytokine-induced members of the dynamin superfamily with unique GTPase activity by Vestal, Deborah J

“…The guanylate-binding proteins (GBPs) were first identified in the late 1970s, and within a short period of time, investigators were aware that GBPs possessed…”
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cDNA sequence of the human integrin beta 5 subunit by McLean, J W, Vestal, D J, Cheresh, D A, Bodary, S C

“…A novel integrin receptor involved in cell adhesion to the matrix protein vitronectin has recently been described from a human lung epithelial-derived cell…”
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T-cadherin 2: molecular characterization, function in cell adhesion, and coexpression with T-cadherin and N-cadherin by Sacristán, M P, Vestal, D J, Dours-Zimmermann, M T, Ranscht, B

“…Cadherins are integral membrane glycoproteins that mediate calcium-dependent, homophilic cell-cell adhesion and are implicated in controlling tissue…”
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Induction of a prenylated 65-kd protein in macrophages by interferon or lipopolysaccharide by Vestal, D J, Maki, R A, Buss, J E

“…Treatment of murine bone marrow-derived macrophages with interferon-gamma (IFN-gamma) and/or lipopolysaccharide (LPS) resulted in changes in the abundance of a…”
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The interferon (IFN)-induced GTPase, mGBP-2. Role in IFN-gamma-induced murine fibroblast proliferation by Gorbacheva, Victoria Y, Lindner, Daniel, Sen, Ganes C, Vestal, Deborah J

“…To investigate the function of mGBP-2, a member of the interferon (IFN)-induced guanylate-binding protein family of GTPases, NIH 3T3 fibroblasts were generated…”
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DRBP76, a Double-stranded RNA-binding Nuclear Protein, Is Phosphorylated by the Interferon-induced Protein Kinase, PKR by Patel, R C, Vestal, D J, Xu, Z, Bandyopadhyay, S, Guo, W, Erme, S M, Williams, B R, Sen, G C

“…The interferon-induced double-stranded RNA-activated protein kinase PKR is the prototype of a class of double-stranded (dsRNA)-binding proteins (DRBPs) which…”
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A rapid redistribution of the transferrin receptor to the cell surface of HL-60 cells and K562 cells upon treatment with dimethyl sulfoxide due to slowing of endocytosis by Vestal, D J, Davis, B H, Enns, C A

“…Treatment of two human leukemia cell lines with 1.25% dimethyl sulfoxide at 37 degrees C results in a rapid increase in the number of transferrin receptors on…”
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In silico genomic analysis of the human and murine guanylate-binding protein (GBP) gene clusters by Olszewski, Maureen A, Gray, John, Vestal, Deborah J

“…The guanylate-binding proteins (GBPs) were among the first interferon (IFN)-stimulated genes (ISGs) discovered, but until recently, little was known about…”
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Murine GBP-2: a new IFN-gamma-induced member of the GBP family of GTPases isolated from macrophages by Vestal, D J, Buss, J E, McKercher, S R, Jenkins, N A, Copeland, N G, Kelner, G S, Asundi, V K, Maki, R A

“…We have cloned a new member of the interferon (IFN)-induced guanylate-binding protein (GBP) family of GTPases, murine GBP-2 (mGBP-2), from bone marrow-derived…”
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Rat p67 GBP Is Induced by Interferon-γ and Isoprenoid-Modified in Macrophages by Vestal, Deborah J., Buss, Janice E., Kelner, Gregory S., Maciejewski, Dominique, Asundi, Vinod K., Maki, Richard A.

“…The guanylate binding proteins, GBPs, are a family of interferon-induced GTP-binding proteins that include the rat p67. We report here that rat p67, for which…”
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Role of GTP binding, isoprenylation, and the C-terminal α-helices in the inhibition of cell spreading by the interferon-induced GTPase, mouse guanylate-binding protein-2 by Balasubramanian, Sujata, Messmer-Blust, Angela F, Jeyaratnam, Jonathan A, Vestal, Deborah J

“…Interferon-γ pre-exposure inhibits Rac activation by either integrin engagement or platelet-derived growth factor treatment. Interferon-γ does this by inducing…”
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Purification and functional characterization of integrin αvβ5. An adhesion receptor for vitronectin by SMITH, J. W, VESTAL, D. J, IRWIN, S. V, BURKE, T. A, CHERESH, D. A

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T-cadherin 2: Molecular characterization, function in cell adhesion, and coexpression with T-cadherin and N-cadherin by Sacristan, M P, Vestal, D J, Dours-Zimmermann, M T, Ranscht, B

“…Cadherins are integral membrane glycoproteins that mediate calcium-dependent, homophilic cell-cell adhesion and are implicated in controlling tissue…”
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Purification and functional characterization of integrin alpha sub(v) beta sub(5). An adhesion receptor for vitronectin by Smith, J W, Vestal, D J, Irwin, S V, Burke, T A, Cheresh, DA

“…We have purified a novel member of the integrin gene family from placenta that serves as a vitronectin receptor. This integrin is composed of the alpha sub(v)…”
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