Search Results - "Vessillier, S"

Cytokine release assays for the prediction of therapeutic mAb safety in first-in man trials — Whole blood cytokine release assays are poorly predictive for TGN1412 cytokine storm by Vessillier, S., Eastwood, D., Fox, B., Sathish, J., Sethu, S., Dougall, T., Thorpe, S.J., Thorpe, R., Stebbings, R.

“…The therapeutic monoclonal antibody (mAb) TGN1412 (anti-CD28 superagonist) caused near-fatal cytokine release syndrome (CRS) in all six volunteers during a…”
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Oxygen tension modulates the effects of TNFα in compressed chondrocytes by Tilwani, R. K., Vessillier, S., Pingguan-Murphy, B., Lee, D. A., Bader, D. L., Chowdhury, T. T.

“…Objective and design Oxygen tension and biomechanical signals are factors that regulate inflammatory mechanisms in chondrocytes. We examined whether low oxygen…”
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C-type natriuretic peptide signalling drives homeostatic effects in human chondrocytes by Peake, N.J., Bader, D.L., Vessillier, S., Ramachandran, M., Salter, D.M., Hobbs, A.J., Chowdhury, T.T.

“…Signals induced by mechanical loading and C-type natriuretic peptide (CNP) represent chondroprotective routes that may potentially prevent osteoarthritis (OA)…”
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α5β1 integrin mediates compression-induced inhibition of catabolic effects induced by fibronectin fragments in an oxygen-dependent manner by Parker, E, Vessillier, S, Abas, W. Wan, Bader, D.L, Pinguaan-Murphy, B, Chowdhury, T.T

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Reference reagents for a better harmonisation of Cytokine Release Assays by Vessillier, S.

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Latent cytokines: development of novel cleavage sites and kinetic analysis of their differential sensitivity to MMP-1 and MMP-3 by Vessillier, Sandrine, Adams, Gill, Chernajovsky, Yuti

“…We have engineered a latent mouse interferon β (mIFNβ) using the latency associated peptide (LAP) of transforming growth factor β1 (TGF-β1) to protect the…”
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1045 - Immunotherapy: LENTISTIM VECTOR PLATFORM: SIMULTANEOUS TRANSDUCTION AND ACTIVATION OF T LYMPHOCYTES FOR IMPROVED CAR T CELL IN VIVO FUNCTION by Labbé, R., Takeuchi, Y., Vessillier, S., Rafiq, Q.A.

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Gene Editing/Gene Therapies: LENTIVIRAL VECTOR PLATFORM DEVELOPMENT FOR IMPROVED CHIMERIC ANTIGEN RECEPTOR T CELL APPLICATIONS by Labbé, R., Takeuchi, Y., Vessillier, S., Rafiq, Q.A.

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Immunotherapy: LENTISTIM VECTOR PLATFORM: SIMULTANEOUS TRANSDUCTION AND ACTIVATION OF T LYMPHOCYTES FOR IMPROVED CAR T CELL IN VIVO FUNCTION by Labbé, R., Takeuchi, Y., Vessillier, S., Rafiq, Q.A.

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Overproduction and Biochemical Characterization of the Chryseobacterium meningosepticum BlaB Metallo-β-Lactamase by VESSILLIER, Sandrine, DOCQUIER, Jean-Denis, RIVAL, Sandrine, FRERE, Jean-Marie, GALLENI, Moreno, AMICOSANTE, Gianfranco, ROSSOLINI, Gian Maria, FRANCESCHINI, Nicola

“…Classifications Services AAC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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Meropenem stability to β-lactamase hydrolysis and comparative in vitro activity against several β-lactamase-producing Gram-negative strains by Franceschini, N., Segatore, B., Perilli, M., Vessillier, S., Franchino, L., Amicosante, G.

“…The interaction between meropenem and class A, B, C and D β-lactamases was studied by a spectrophotometric method. Class A, C and D β-lactamases were unable to…”
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Oxygen tension modulates the effects of TNF[alpha] in compressed chondrocytes by Tilwani, R K, Vessillier, S, Pingguan-murphy, B, Lee, D A, Bader, D L, Chowdhury, T T

“…Objective and design Oxygen tension and biomechanical signals are factors that regulate inflammatory mechanisms in chondrocytes. We examined whether low oxygen…”
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Targeting cytokines to inflammation sites by Vessillier, Sandrine, Chernajovsky, Yuti, Adams, Gill, Dreja, Hanna

“…To increase the half-life of a cytokine and target its activation specifically to disease sites, we have engineered a latent cytokine using the…”
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Methods for targeting biologicals to specific disease sites by Nissim, Ahuva, Gofur, Yarunnessa, Vessillier, Sandrine, Adams, Gill, Chernajovsky, Yuti

“…Cytokines are mediators of cell communication. Their therapeutic use requires frequent high doses to achieve effective local biological levels. However, the…”
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Meropenem stability to [beta]-lactamase hydrolysis and comparative in vitro activity against several [beta]-lactamase-producing Gram-negative strains by Franceschini, N, Segatore, B, Perilli, M, Vessillier, S, Franchino, L, Amicosante, G

“…The interaction between meropenem and class A, B, C and D [beta]-lactamases was studied by a spectrophotometric method. Class A, C and D [beta]-lactamases were…”
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Capillary electrophoresis in the assay of the hydrolysis of glycine-containing peptides by a protease from Pseudomonas aeruginosa by Vessillier, Sandrine, Bernillon, Jacques, Saulnier, Joëlle, Wallach, Jean

“…A rapid and simple capillary zone electrophoresis (CZE) method for measuring the activity of a minor protease from Pseudomonas aeruginosa is described. When…”
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Development of new molecules, vectors and cells for therapy of arthritis by Chernajovsky, Yuti, Vessillier, Sandrine, Adams, Gill, Gofur, Yarunessa, Cristina Subang, M., Annenkov, Alex, Favorov, Peter, Daly, Gordon, Gould, David

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Hydrolysis of glycine‐containing elastin pentapeptides by LasA, a metalloelastase from Pseudomonas aeruginosa by Vessillier, Sandrine, Delolme, Frédéric, Bernillon, Jacques, Saulnier, Joëlle, Wallach, Jean

“…Pseudomonas aeruginosa is an opportunistic pathogen that causes severe infections in vulnerable hosts. It may produce various virulence factors including…”
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