Search Results - "Vesely, D."

Cancer immunoediting: antigens, mechanisms, and implications to cancer immunotherapy by Vesely, Matthew D., Schreiber, Robert D.

“…Accumulated data from animal models and human cancer patients strongly support the concept that the immune system can identify and control nascent tumor cells…”
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Natural innate and adaptive immunity to cancer by Vesely, Matthew D, Kershaw, Michael H, Schreiber, Robert D, Smyth, Mark J

“…The immune system can identify and destroy nascent tumor cells in a process termed cancer immunosurveillance, which functions as an important defense against…”
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Paradoxical eruptions to targeted therapies in dermatology: A systematic review and analysis by Murphy, Michael J., Cohen, Jeffrey M., Vesely, Matthew D., Damsky, William

“…Antibody-based therapies that inhibit proinflammatory cytokine signaling are commonly used in dermatology. Paradoxically, these medications may induce or…”
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Demonstration of inflammation-induced cancer and cancer immunoediting during primary tumorigenesis by Swann, Jeremy B, Vesely, Matthew D, Silva, Anabel, Sharkey, Janelle, Akira, Shizuo, Schreiber, Robert D, Smyth, Mark J

“…Here we report the effects of loss of the Toll-like receptor-associated signaling adaptor myeloid-differentiation factor 88 (MyD88) on tumor induction in two…”
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Resistance Mechanisms to Anti-PD Cancer Immunotherapy by Vesely, Matthew D, Zhang, Tianxiang, Chen, Lieping

“…The transformative success of antibodies targeting the PD-1 (programmed death 1) B7-H1 (B7 homolog 1) pathway (anti-PD therapy) has revolutionized cancer…”
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Opposing Roles for IL-23 and IL-12 in Maintaining Occult Cancer in an Equilibrium State by TENG, Michele W. L, VESELY, Matthew D, DURET, Helene, MCLAUGHLIN, Nicole, TOWNE, Jennifer E, SCHREIBER, Robert D, SMYTH, Mark J

“…Cancer immunoediting, the process by which the immune system controls tumor growth and shapes tumor immunogenicity, consists of 3 stages: elimination,…”
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Treatment of cutaneous lupus with topical ruxolitinib cream by Park, Jonathan J., Little, Alicia J., Vesely, Matthew D.

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Pembrolizumab-induced lichenoid dermatitis treated with dupilumab by Park, Jonathan J., Park, Eunsuh, Damsky, William E., Vesely, Matthew D.

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Remission of severe atopic dermatitis with dupilumab and rescue tofacitinib therapy by Peterson, Danielle M., Vesely, Matthew D.

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Treatment of lichen sclerosus and hypertrophic scars with dupilumab by Peterson, Danielle M., Damsky, William E., Vesely, Matthew D.

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Successful treatment of alopecia totalis with ruxolitinib in a preadolescent patient by Peterson, Danielle M., Vesely, Matthew D.

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Clinical and research updates on the VISTA immune checkpoint: immuno-oncology themes and highlights by Noelle, Randolph J., Lines, J. Louise, Lewis, Lionel D., Martell, Robert E., Guillaudeux, Thierry, Lee, Sam W., Mahoney, Kathleen M., Vesely, Matthew D., Boyd-Kirkup, Jerome, Nambiar, Dhanya K., Scott, Andrew M.

“…Immune checkpoints limit the activation of the immune system and serve an important homeostatic function but can also restrict immune responses against tumors…”
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Redox-Sensitive Sulfenic Acid Modification Regulates Surface Expression of the Cardiovascular Voltage-Gated Potassium Channel Kv1.5 by Svoboda, Laurie K, Reddie, Khalilah G, Zhang, Lian, Vesely, Eileen D, Williams, Elizabeth S, Schumacher, Sarah M, OʼConnell, Ryan P, Shaw, Robin, Day, Sharlene M, Anumonwo, Justus M, Carroll, Kate S, Martens, Jeffrey R

“…RATIONALE:Kv1.5 (KCNA5) is expressed in the heart, where it underlies the IKur current that controls atrial repolarization, and in the pulmonary vasculature,…”
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Intermediate to Long-Term Follow-up of the Salto Talaris Fixed-Bearing Total Ankle Prosthesis by Vesely, Bryanna D., King, Matthew A., Scott, Aaron T.

“…Background Total ankle arthroplasty (TAA) remains a viable option for recalcitrant, end-stage ankle arthritis. Among the various Food and Drug Administration…”
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Onychodystrophy associated with dupilumab therapy for atopic dermatitis by Zubek, Amanda E., Vesely, Matthew D.

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HIF-1 regulates pathogenic cytotoxic T cells in lupus skin disease by Little, Alicia J, Chen, Ping-Min, Vesely, Matthew D, Khan, Rahanna N, Fiedler, Jacob, Garritano, James, Maisha, Fahrisa I, McNiff, Jennifer M, Craft, Joe

“…Cutaneous lupus erythematosus (CLE) is a disfiguring autoimmune skin disease characterized by an inflammatory infiltrate rich in T cells, which are strongly…”
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Up-regulated PLA2G10 in cancer impairs T cell infiltration to dampen immunity by Zhang, Tianxiang, Yu, Weiwei, Cheng, Xiaoxiao, Yeung, Jacky, Ahumada, Viviana, Norris, Paul C, Pearson, Mackenzie J, Yang, Xuan, van Deursen, Willemijn, Halcovich, Christina, Nassar, Ala, Vesely, Mathew D, Zhang, Yu, Zhang, Jianping, Ji, Lan, Flies, Dallas B, Liu, Linda, Langermann, Solomon, LaRochelle, William J, Humphrey, Rachel, Zhao, Dejian, Zhang, Qiuyu, Zhang, Jindong, Gu, Runxia, Schalper, Kurt A, Sanmamed, Miguel F, Chen, Lieping

“…T cells are often absent from human cancer tissues during both spontaneously induced immunity and therapeutic immunotherapy, even in the presence of a…”
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Amelanotic melanoma in a patient with Hermansky-Pudlak syndrome by Fan, Ryan, Johnston, Margaret S., Gowen, Michael F., Damsky, William, Odell, Ian, Clune, James, Vesely, Matthew D.

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Cytokine RNA In Situ Hybridization Permits Individualized Molecular Phenotyping in Biopsies of Psoriasis and Atopic Dermatitis by Wang, Alice, Fogel, Alexander L., Murphy, Michael J., Panse, Gauri, McGeary, Meaghan K., McNiff, Jennifer M., Bosenberg, Marcus, Vesely, Matthew D., Cohen, Jeffrey M., Ko, Christine J., King, Brett A., Damsky, William

“…Detection of individual cytokines in routine biopsies from patients with inflammatory skin diseases has the potential to personalize diagnosis and treatment…”
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Polycomb-dependent repression of the potassium channel-encoding gene KCNA5 promotes cancer cell survival under conditions of stress by Ryland, K E, Svoboda, L K, Vesely, E D, McIntyre, J C, Zhang, L, Martens, J R, Lawlor, E R

“…Relapse after clinical remission remains a leading cause of cancer-associated death. Although the mechanisms of tumor relapse are complex, the ability of…”
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