Search Results - "Veselovsky, A. V"

Renalase, a new secretory enzyme responsible for selective degradation of catecholamines: Achievements and unsolved problems by Medvedev, A. E, Veselovsky, A. V, Fedchenko, V. I

“…Renalase is a recently discovered secretory enzyme responsible for selective degradation of blood catecholamines. The review summarizes literature data on…”
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Lipid peroxidation, carbohydrate hydrolysis, and Amadori-Maillard reaction at early stages of dry seed aging by Veselovsky, V. A, Veselova, T. V

“…Processes underlying aging of air-dry seeds were investigated. Naturally aged seeds of pea (Pisum sativum L.), cucumber (Cucumis sativus L.), and buckwheat…”
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Protein-protein interactions: mechanisms and modification by drugs by Veselovsky, A. V., Ivanov, Yu. D., Ivanov, A. S., Archakov, A. I., Lewi, P., Janssen, P.

“…Protein–protein interactions form the proteinaceous network, which plays a central role in numerous processes in the cell. This review highlights the main…”
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Electrochemical Analysis of the Interaction between DNA and Abiraterone D4A Metabolite by Shumyantseva, V. V., Berezhnova, A. V., Agafonova, L. E., Bulko, T. V., Veselovsky, A. V.

“…The electroanalytical characteristics of double-stranded DNA (dsDNA) and the complex of dsDNA with the anticancer drug metabolite, abiraterone D4A, in the…”
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Ligand–Receptor Binding Kinetics in Drug Design by Borisov, D. V., Veselovsky, A.V.

“…Traditionally, the thermodynamic affinity is considered as the main criterion for the development of new drugs. In most cases these thermodynamic affinity…”
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The search for potential hypotensive peptides in the amino acid sequence of human renalase and their identification in proteolytic fragments of this protein by Fedchenko, V I, Veselovsky, A V, Kopylov, A T, Medvedev, A E

“…Renalase (RNLS) is a secretory protein discovered in 2005. It plays an important role in the regulation of blood pressure. Studies by two independent…”
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Interaction of Abiraterone and Its Pharmacologically Active Metabolite D4A with Cytochrome P450 2C9 (CYP2C9) by Masamrekh, R. A., Kuzikov, A. V., Filippova, T. A., Sherbakov, K. A., Veselovsky, A. V., Shumyantseva, V. V.

“…We studied the interaction of the antitumor agent abiraterone and its pharmacologically active metabolite D4A, which is promising for use as an agent for the…”
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Identification of functional regions in the Rhodospirillum rubrum L-asparaginase by site-directed mutagenesis by Pokrovskaya, M V, Aleksandrova, S S, Pokrovsky, V S, Veselovsky, A V, Grishin, D V, Abakumova, O Yu, Podobed, O V, Mishin, A A, Zhdanov, D D, Sokolov, N N

“…Site-directed mutagenesis of Rhodospirillum rubrum L-asparaginase (RrA) was performed in order to identify sites of the protein molecule important for its…”
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An improved and extended dual-index multiplexed 16S rRNA sequencing for the Illumina HiSeq and MiSeq platform by Larin, A K, Klimina, K M, Veselovsky, V A, Olekhnovich, E I, Morozov, M D, Boldyreva, D I, Yunes, R A, Manolov, A I, Fedorov, D E, Pavlenko, A V, Galeeva, Y S, Starikova, E V, Ilina, E N

“…Recent advancements in next-generation sequencing (NGS) technology have ushered in significant improvements in sequencing speed and data throughput, thereby…”
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Gut Microbiome as a Predictor of the Anti-PD-1 Therapy Success: Metagenomic Data Analysis by Fedorov, D. E., Pavlenko, A. V., Olekhnovich, E. I., Klimina, K. M., Pokataev, I. A., Manolov, A. I., Konanov, D. N., Veselovsky, V. A., Ilina, E. N.

“…— Anti-PD-1 immunotherapy has a large impact on cancer treatment but the rate of positive treatment outcomes is 40–45% and depends on many factors. One of the…”
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Determination of Amino Acid Residues Responsible for Specific Interaction of Protein Kinases with Small Molecule Inhibitors by Karasev, D. A., Veselovsky, A. V., Lagunin, A. A., Filimonov, D. A., Sobolev, B. N.

“…Identifying amino acid positions that determine the specific interaction of proteins with small molecule ligands, is required for search of pharmaceutical…”
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Evaluation of the Levels of Metabolites in Feces of Patients with Inflammatory Bowel Diseases by Zhgun, E. S., Kislun, Y. V., Kalachniuk, T. N., Veselovsky, V. A., Urban, A. S., Tikhonova, P. O., Pavlenko, A. V., Ilchenko, G. N., Ilina, E. N.

“…— Inflammatory bowel diseases (IBD), which include ulcerative colitis (UC) and Crohn’s disease (CD), are chronic intestinal inflammatory disorders with only…”
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Electrochemical oxidation of thrombin on carbon screen printed electrodes by Suprun, E. V., Zharkova, M. S., Veselovsky, A. V., Archakov, A. I., Shumyantseva, V. V.

“…The electrochemical oxidation of thrombin on the surface of carbon screen printed electrodes was studied. The electrochemical activity of thrombin was…”
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New inhibitors of 5-lipoxygenase catalytic activity based on 2-(3-methylphenyl)propanoic acid and 4-substituted morpholine derivatives by Khayrullina, V. R., Taipov, I. A., Veselovsky, A. V., Shcherbinin, D. S., Gerchikov, A. Ya

“…New potential inhibitors of 5-lipoxygenase (5-LOX) based on the structure of 2-(3-benzoylphenyl)propanoic acid (an active component of the nonsteroidal…”
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Computer-aided design and discovery of protein-protein interaction inhibitors as agents for anti-HIV therapy by Veselovsky, A.V., Zharkova, M.S., Poroikov, V.V., Nicklaus, M.C.

“…Protein-protein interactions (PPI) are involved in most of the essential processes that occur in organisms. In recent years, PPI have become the object of…”
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Comparative Genomics of the Escherichia coli Strains АВ1157, АВ2463, АВ2494, and АВ1885 by Smirnov, G. B., Bodoev, I. N., Makarova, A. P., Butusova, T. B., Veselovsky, V. A., Gulyaev, A. S., Shitikov, E. A., Ilina, E. N.

“…Whole genome sequencing of the Escherichia coli strain АВ1157 and its mutants AB1885 uvrB5 , AB2463 recA13 , and AB2494 lexA1 , which have deficient DNA…”
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Bacterial TEM-Type Serine Beta-Lactamases: Structure and Analysis of Mutations by Grigorenko, V. G., Rubtsova, M. Yu, Uporov, I. V., Ishtubaev, I. V., Andreeva, I. P., Shcherbinin, D. S., Veselovsky, A. V., Egorov, A. M.

“…Beta-lactamases (EC 3.5.2.6) represent a superfamily containing more than 2000 members: it includes genetically and functionally different bacterial enzymes…”
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Computer modelling of monoamine oxidases by Veselovsky, A. V., Ivanov, A. S., Medvedev, A. E.

“…The article summarized results of long-term studies on active site structures of monoamine oxidase (MAO) performed in the Institute of Biomedical Chemistry…”
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Identification of Functional Regions in the Rhodospirillum rubruml-Asparaginase by Site-Directed Mutagenesis by Pokrovskaya, M. V., Aleksandrova, S. S., Pokrovsky, V. S., Veselovsky, A. V., Grishin, D. V., Abakumova, O. Yu, Podobed, O. V., Mishin, A. A., Zhdanov, D. D., Sokolov, N. N.

“…Site-directed mutagenesis of Rhodospirillum rubrum l -asparaginase (RrA) was performed in order to identify sites of the protein molecule important for its…”
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The history of renalase from amine oxidase to α-NAD(P)H-oxidase/anomerase by Severina, I. S., Fedchenko, V. I., Veselovsky, A. V., Medvedev, A. E.

“…Renalase is a recently discovered secretory protein, which plays a certain (still poorly understood) role in regulation of blood pressure. The review…”
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