Search Results - "Veselenak, Ronald L"

Virus-specific immune memory at peripheral sites of herpes simplex virus type 2 (HSV-2) infection in guinea pigs by Xia, Jingya, Veselenak, Ronald L, Gorder, Summer R, Bourne, Nigel, Milligan, Gregg N

“…Despite its importance in modulating HSV-2 pathogenesis, the nature of tissue-resident immune memory to HSV-2 is not completely understood. We used genital…”
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Development and Utilization of a Custom PCR Array Workflow: Analysis of Gene Expression in Mycoplasma genitalium and Guinea Pig (Cavia porcellus) by Veselenak, Ronald L, Miller, Aaron L, Milligan, Gregg N, Bourne, Nigel, Pyles, Richard B

“…Transcriptome analysis is a powerful tool for evaluating molecular pathways central to maturation of specific biological processes and disease states…”
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Use of a Guinea pig-specific transcriptome array for evaluation of protective immunity against genital chlamydial infection following intranasal vaccination in Guinea pigs by Wali, Shradha, Gupta, Rishein, Veselenak, Ronald L, Li, Yansong, Yu, Jieh-Juen, Murthy, Ashlesh K, Cap, Andrew P, Guentzel, M Neal, Chambers, James P, Zhong, Guangming, Rank, Roger G, Pyles, Richard B, Arulanandam, Bernard P

“…Guinea pigs have been used as a second animal model to validate putative anti-chlamydial vaccine candidates tested in mice. However, the lack of guinea…”
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Inhibition of Hepatitis C Virus Replicon RNA Synthesis by PSI-352938, a Cyclic Phosphate Prodrug of β-d-2′-Deoxy-2′-α-Fluoro-2′-β-C-Methylguanosine by LAM, Angela M, ESPIRITU, Christine, VESELENAK, Ronald L, GANAPATI REDDY, P, CHANG, Wonsuk, JINFA DU, NAGARATHNAM, Dhanapalan, SOFIA, Michael J, OTTO, Michael J, FURMAN, Phillip A, MURAKAMI, Eisuke, ZENNOU, Veronique, BANSAL, Shalini, MICOLOCHICK STEUER, Holly M, CONGRONG NIU, KEILMAN, Meg, HAIYING BAO, BOURNE, Nigel

“…Classifications Services AAC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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A Vaxfectin® -adjuvanted HSV-2 plasmid DNA vaccine is effective for prophylactic and therapeutic use in the guinea pig model of genital herpes by Veselenak, Ronald L, Shlapobersky, Mark, Pyles, Richard B, Wei, Qun, Sullivan, Sean M, Bourne, Nigel

“…Highlights ► Vaxfectin-gD2/UL46/UL47 DNA vaccine effective against genital herpes in guinea pigs. ► Prophylactic immunization prevents primary and recurrent…”
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The Fibroblast Growth Factor 14·Voltage-gated Sodium Channel Complex Is a New Target of Glycogen Synthase Kinase 3 (GSK3) by Shavkunov, Alexander S., Wildburger, Norelle C., Nenov, Miroslav N., James, Thomas F., Buzhdygan, Tetyana P., Panova-Elektronova, Neli I., Green, Thomas A., Veselenak, Ronald L., Bourne, Nigel, Laezza, Fernanda

“…The FGF14 protein controls biophysical properties and subcellular distribution of neuronal voltage-gated Na+ (Nav) channels through direct binding to the…”
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Transcriptional Analysis of the Guinea Pig Mucosal Immune Response to Intravaginal Infection with Herpes Simplex Virus Type 2 by Veselenak, Ronald L., Milligan, Gregg N., Miller, Aaron L., Pyles, Richard B., Bourne, Nigel

“…Genital herpes infection in guinea pigs closely models human infection but tools for immune characterization are limited. Immunity to HSV infection at the…”
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Activity and the metabolic activation pathway of the potent and selective hepatitis C virus pronucleotide inhibitor PSI-353661 by Furman, Phillip A., Murakami, Eisuke, Niu, Congrong, Lam, Angela M., Espiritu, Christine, Bansal, Shalini, Bao, Haiying, Tolstykh, Tatiana, Micolochick Steuer, Holly, Keilman, Meg, Zennou, Veronique, Bourne, Nigel, Veselenak, Ronald L., Chang, Wonsuk, Ross, Bruce S., Du, Jinfa, Otto, Michael J., Sofia, Michael J.

“…PSI-353661, a phosphoramidate prodrug of 2′-deoxy-2′-fluoro-2′- C-methylguanosine-5′-monophosphate, is a highly active inhibitor of genotype 1a, 1b, and 2a HCV…”
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In vivo evaluation of antiviral efficacy against genital herpes using mouse and guinea pig models by Valencia, Frances, Veselenak, Ronald L, Bourne, Nigel

“…Both the guinea pig and mouse are important animal models for the study of genital herpes. The murine model has been used extensively to evaluate vaccines and…”
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Mutations conferring resistance to SCH6, a novel hepatitis C virus NS3/4A protease inhibitor. Reduced RNA replication fitness and partial rescue by second-site mutations by Yi, MinKyung, Tong, Xiao, Skelton, Angela, Chase, Robert, Chen, Tong, Prongay, Andrew, Bogen, Stephane L, Saksena, Anil K, Njoroge, F George, Veselenak, Ronald L, Pyles, Richard B, Bourne, Nigel, Malcolm, Bruce A, Lemon, Stanley M

“…Drug resistance is a major issue in the development and use of specific antiviral therapies. Here we report the isolation and characterization of hepatitis C…”
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Screening for hepatitis C virus antiviral activity with a cell-based secreted alkaline phosphatase reporter replicon system by Bourne, Nigel, Pyles, Richard B., Yi, MinKyung, Veselenak, Ronald L., Davis, Melissa M., Lemon, Stanley M.

“…We describe a phased screening system for discovery of compounds with antiviral activity against hepatitis C virus (HCV). The primary assay utilizes…”
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Mutations Conferring Resistance to SCH6, a Novel Hepatitis C Virus NS3/4A Protease Inhibitor by Yi, MinKyung, Tong, Xiao, Skelton, Angela, Chase, Robert, Chen, Tong, Prongay, Andrew, Bogen, Stephane L., Saksena, Anil K., Njoroge, F. George, Veselenak, Ronald L., Pyles, Richard B., Bourne, Nigel, Malcolm, Bruce A., Lemon, Stanley M.

“…Drug resistance is a major issue in the development and use of specific antiviral therapies. Here we report the isolation and characterization of hepatitis C…”
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Virus-Specific Immune Memory at Peripheral Sites of Herpes Simplex Virus Type 2 by Xia, Jingya, Veselenak, Ronald L, Gorder, Summer R, Bourne, Nigel, Milligan, Gregg N

“…Despite its importance in modulating HSV-2 pathogenesis, the nature of tissue-resident immune memory to HSV-2 is not completely understood. We used genital…”
Get full text

A VaxfectinARG-adjuvanted HSV-2 plasmid DNA vaccine is effective for prophylactic and therapeutic use in the guinea pig model of genital herpes by Veselenak, Ronald L, Shlapobersky, Mark, Pyles, Richard B, Wei, Qun, Sullivan, Sean M, Bourne, Nigel

“…Here we describe studies in the guinea pig model of genital herpes to evaluate a novel plasmid DNA (pDNA) vaccine encoding the HSV-2 glycoprotein D and UL46…”
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Virus-Specific Immune Memory at Peripheral Sites of Herpes Simplex Virus Type 2 (HSV-2) Infection in Guinea Pigs: e114652 by Xia, Jingya, Veselenak, Ronald L, Gorder, Summer R, Bourne, Nigel, Milligan, Gregg N

“…Despite its importance in modulating HSV-2 pathogenesis, the nature of tissue-resident immune memory to HSV-2 is not completely understood. We used genital…”
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Use of a Guinea Pig-Specific Transcriptome Array for Evaluation of Protective Immunity against Genital Chlamydial Infection following Intranasal Vaccination in Guinea Pigs: e114261 by Wali, Shradha, Gupta, Rishein, Veselenak, Ronald L, Li, Yansong, Yu, Jieh-Juen, Murthy, Ashlesh K, Cap, Andrew P, Guentzel, M Neal, Chambers, James P, Zhong, Guangming

“…Guinea pigs have been used as a second animal model to validate putative anti-chlamydial vaccine candidates tested in mice. However, the lack of guinea…”
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Mutations Conferring Resistance to SCH6, a Novel Hepatitis C Virus NS3/4A Protease Inhibitor: Reduced DNA Replication Fitness and Partial Rescue by Second-Site Mutations by Yi, MinKyung, Tong, Xiao, Skelton, Angela, Chase, Robert, Chen, Tong, Prongay, Andrew, Bogen, Stephane L., Saksena, Anil K., Njoroge, F. George, Veselenak, Ronald L., Pyles, Richard B., Bourne, Nigel, Malcolm, Bruce A., Lemon, Stanley M.

“…Drug resistance is a major issue in the development and use of specific antiviral therapies. Here we report the isolation and characterization of hepatitis C…”
Get full text