Search Results - "Verwey, Nicolaas A."

Discriminative and prognostic potential of cerebrospinal fluid phosphoTau/tau ratio and neurofilaments for frontotemporal dementia subtypes by Pijnenburg, Yolande A.L, Verwey, Nicolaas A, van der Flier, Wiesje M, Scheltens, Philip, Teunissen, Charlotte E

“…Abstract Introduction A decreased cerebrospinal fluid (CSF) p-Tau181 to total tau ratio (p/t-tau) is a biomarker for frontotemporal lobar degeneration with…”
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The impact of tau-PET in a selected memory clinic cohort: rationale and design of the TAP-TAU study by Vermeiren, Marie R, Somsen, Joost, Luurtsema, Gert, Reesink, Fransje E, Verwey, Nicolaas A, Hempenius, Liesbeth, Tolboom, Nelleke, Biessels, Geert Jan, Biesbroek, J Matthijs, Vernooij, Meike W, Veldhuijzen van Zanten, Sophie E M, Seelaar, Harro, Coomans, Emma M, Teunissen, Charlotte E, Lemstra, Afina W, van Harten, Argonde C, Visser, Leonie N C, van der Flier, Wiesje M, van de Giessen, Elsmarieke, Ossenkoppele, Rik

“…Tau-PET is a diagnostic tool with high sensitivity and specificity for discriminating Alzheimer's disease (AD) dementia from other neurodegenerative disorders…”
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Cognitive correlates of cerebrospinal fluid biomarkers in frontotemporal dementia by Koedam, Esther L.G.E, van der Vlies, Annelies E, van der Flier, Wiesje M, Verwey, Nicolaas A, Koene, Ted, Scheltens, Philip, Blankenstein, Marinus A, Pijnenburg, Yolande A.L

“…Abstract Objective In this study we investigated the relationships between cerebrospinal fluid (CSF) biomarkers (tau and amyloid-β1-42 [Aβ1-42 ]) and cognition…”
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Amyloid-β(1-42), Total Tau, and Phosphorylated Tau as Cerebrospinal Fluid Biomarkers for the Diagnosis of Alzheimer Disease by MULDER, Cees, VERWEY, Nicolaas A, VAN DER FLIER, Wiesje M, BOUWMAN, Femke H, KOK, Astrid, VAN ELK, Evert J, SCHELTENS, Philip, BLANKENSTEIN, Marinus A

“…To improve ante mortem diagnostic accuracy of Alzheimer disease (AD), measurement of the biomarkers amyloid-beta(1-42) (Abeta42), total tau (Tau), and tau…”
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Cognitive Impairment in the Outpatient Setting: Experiences and Views of Medical Specialists by Visser, Fleur C.W., Barmentlo, Roos, Luttmer, Thomas, van Zeventer, Roos, van der Werff, Tim, Hempenius, Liesbeth, Verwey, Nicolaas A., van Munster, Barbara C.

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Quantification of amyloid-beta 40 in cerebrospinal fluid by Verwey, Nicolaas A., Veerhuis, Robert, Twaalfhoven, Harry A.M., Wouters, Dorine, Hoozemans, Jeroen J.M., Bollen, Yves J.M., Killestein, Joep, Bibl, Mirko, Wiltfang, Jens, Hack, C. Erik, Scheltens, Philip, Blankenstein, Marinus A.

“…Truncated forms and full-length forms of the amyloid-beta 40 (Aβ40) are key molecules in the pathogenesis of dementia, and are detectable in CSF. Reliable…”
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Serum amyloid p component as a biomarker in mild cognitive impairment and Alzheimer's disease by Verwey, Nicolaas A, Schuitemaker, Alie, van der Flier, Wiesje M, Mulder, Sandra D, Mulder, Cees, Hack, C Erik, Scheltens, Philip, Blankenstein, Marinus A, Veerhuis, Robert

“…Serum amyloid P component (SAP), present in amyloid-beta (Abeta) plaques in Alzheimer's disease (AD), may protect Abeta deposits against proteolysis, thereby…”
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Tau Rather than TDP-43 Proteins are Potential Cerebrospinal Fluid Biomarkers for Frontotemporal Lobar Degeneration Subtypes: A Pilot Study by Kuiperij, H Bea, Versleijen, Alexandra A M, Beenes, Marijke, Verwey, Nicolaas A, Benussi, Luisa, Paterlini, Anna, Binetti, Giuliano, Teunissen, Charlotte E, Raaphorst, Joost, Schelhaas, Helenius J, Küsters, Benno, Pijnenburg, Yolande A L, Ghidoni, Roberta, Verbeek, Marcel M

“…Frontotemporal dementia (FTD) is a heterogeneous disease both at the clinical, genetic, and pathobiological level. The underlying pathological spectrum (termed…”
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CSF biomarker levels in early and late onset Alzheimer's disease by Bouwman, Femke H, Schoonenboom, Niki S.M, Verwey, Nicolaas A, van Elk, Evert J, Kok, Astrid, Blankenstein, Marinus A, Scheltens, Philip, van der Flier, Wiesje M

“…Abstract Objective To compare CSF levels of beta-amyloid 1–42 (Aβ1–42 ), total tau (tau) and tau phosphorylated at threonine 181 (ptau-181) between AD patients…”
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Serial CSF sampling in Alzheimer's disease: specific versus non-specific markers by Kester, Maartje I, Scheffer, Peter G, Koel-Simmelink, Marleen J, Twaalfhoven, Harry, Verwey, Nicolaas A, Veerhuis, Robert, Twisk, Jos W, Bouwman, Femke H, Blankenstein, Marinus A, Scheltens, Philip, Teunissen, Charlotte, van der Flier, Wiesje M

“…Abstract In this longitudinal study we investigated change over time in cerebrospinal fluid (CSF) levels of amyloid-beta 40 and 42 (Aβ40 and Aβ42), total tau…”
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Microbleeds relate to altered amyloid-beta metabolism in Alzheimer's disease by Goos, Jeroen D.C, Teunissen, Charlotte E, Veerhuis, Robert, Verwey, Nicolaas A, Barkhof, Frederik, Blankenstein, Marinus A, Scheltens, Philip, van der Flier, Wiesje M

“…Abstract Cerebral microbleeds (MBs) may relate to amyloid in dementia. We selected 26 probable Alzheimer's disease (AD) patients with MBs, 26 age- and…”
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Young-onset dementia in memory clinics in the Netherlands: Study design and description of PRECODE-GP by van Gils, Aniek M, Rhodius-Meester, Hanneke F M, Leeuwis, Anna E, Handgraaf, Dédé, Bakker, Christian, Peetoom, Kirsten, Bouwman, Femke H, Pijnenburg, Yolande A L, Papma, Janne M, Hoogendoorn, Tanja-Anne, Schoonenboom, Niki, van Strien, Astrid, Verwey, Nicolaas A, Köhler, Sebastian, de Vugt, Marjolein E, van der Flier, Wiesje M

“…The disease trajectory and healthcare requirements of patients with young-onset dementia (YOD) differ from those of older patients. Accurate data about YOD is…”
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Cerebrospinal Fluid β-Amyloid and Tau Are Not Associated with Risk of Delirium: A Prospective Cohort Study in Older Adults with Hip Fracture by Witlox, Joost, Kalisvaart, Kees J., de Jonghe, Jos F.M., Verwey, Nicolaas A., van Stijn, Mireille F.M., Houdijk, Alexander P.J., Traast, Han S., MacLullich, Alasdair M.J., van Gool, Willem A., Eikelenboom, Piet

“…OBJECTIVES: To examine the association between cerebrospinal fluid (CSF) β‐amyloid (Aβ1–42), tau, and hyperphosphorylated tau (Ptau) and risk of delirium in…”
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Clinico-Pathological Correlations of the Frontal Lobe Syndrome: Results of a Large Brain Bank Study by Krudop, Welmoed A, Bosman, Sjanne, Geurts, Jeroen J G, Sikkes, Sietske A M, Verwey, Nicolaas A, Stek, Max L, Scheltens, Philip, Rozemuller, Annemieke J M, Pijnenburg, Yolande A L

“…A clinical frontal lobe syndrome (FLS) is generally attributed to functional or structural disturbances within frontal-subcortical circuits. We studied the…”
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Evaluation of plasma Aβ40 and Aβ42 as predictors of conversion to Alzheimer's disease in patients with mild cognitive impairment by Kester, Maartje I, Verwey, Nicolaas A, van Elk, Evert J, Scheltens, Philip, Blankenstein, Marinus A

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Progression from MCI to AD: Predictive value of CSF A beta 42 is modified by APOE genotype by Kester, Maartje I, Verwey, Nicolaas A, Van Elk, Evert J, Blankenstein, Marinus A, Scheltens, Philip, Van der Flier, Wiesje M

“…To study CSF biomarkers amyloid-beta 1-42 (A beta 42) and total tau (tau) in relation to APOE genotype in their ability to predict progression from mild…”
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Progression from MCI to AD: Predictive value of CSF Aβ42 is modified by APOE genotype by Kester, Maartje I, Verwey, Nicolaas A, van Elk, Evert J, Blankenstein, Marinus A, Scheltens, Philip, van der Flier, Wiesje M

“…Abstract Objective To study CSF biomarkers amyloid-beta 1–42 (Aβ42) and total tau (tau) in relation to APOE genotype in their ability to predict progression…”
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Immunohistochemical characterization of novel monoclonal antibodies against the N-terminus of amyloid β-peptide by Verwey, Nicolaas A., Hoozemans, Jeroen J.M., Korth, Carsten, van Royen, Marloes R., Prikulis, Ingrid, Wouters, Dorine, Twaalfhoven, Harry A.M., van Haastert, Elise S., Schenk, Dale, Scheltens, Philip, Rozemuller, Annemieke J.M., Blankenstein, Marinus A., Veerhuis, Robert

“…Abstract Amyloid β-peptide (Aβ) is a key molecule in Alzheimer's disease (AD). Reliable immunohistochemical (IHC) methods to detect Aβ and Aβ-associated…”
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Variability in longitudinal cerebrospinal fluid tau and phosphorylated tau measurements by Verwey, Nicolaas A, Bouwman, Femke H, van der Flier, Wiesje M, Veerhuis, Rob, Scheltens, Philip, Blankenstein, Marinus A

“…The influence of assay variation and duration of storage on changes in cerebrospinal fluid (CSF) levels of tau and phosphorylated (P)-tau with time was…”
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Relationship of cerebrospinal fluid biomarkers with in vivo [11C]PIB and [18F]FDDNP binding by van Berckel, Bart N.M, Tolboom, Nelleke, van der Flier, Wiesje M, Yaqub, Maqsood, Boellaard, Ronald, Verwey, Nicolaas A, Blankenstein, Marinus A, Luurtsema, Gert, Windhorst, Albert D, Lammertsma, Adriaan A, Scheltens, Philip

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