Search Results - "Verweij, Paul"

Azole resistance in Aspergillus fumigatus: a growing public health concern by Vermeulen, Edith, Lagrou, Katrien, Verweij, Paul E

“…PURPOSE OF REVIEWReports from the end of the 2000s forced the medical community to take azole resistance in Aspergillus fumigatus into account. Not only…”
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Fungal Fog in Viral Storms: Necessity for Rigor in Aspergillosis Diagnosis and Research by Feys, Simon, Hoenigl, Martin, Gangneux, Jean-Pierre, Verweij, Paul E, Wauters, Joost

“…Fungal superinfections in patients with severe viral pneumonia, such as inuenza or COVID-19, are often underdiagnosed due to variations in diagnostic…”
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Azole Resistance in Aspergillus fumigatus: Can We Retain the Clinical Use of Mold-Active Antifungal Azoles? by Verweij, Paul E., Chowdhary, Anuradha, Melchers, Willem J.G., Meis, Jacques F.

“…Azole resistance in Aspergillus fumigatus has emerged as a global health problem. Although the number of cases of azole-resistant aspergillosis is still…”
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Tackling the emerging threat of antifungal resistance to human health by Fisher, Matthew C., Alastruey-Izquierdo, Ana, Berman, Judith, Bicanic, Tihana, Bignell, Elaine M., Bowyer, Paul, Bromley, Michael, Brüggemann, Roger, Garber, Gary, Cornely, Oliver A., Gurr, Sarah. J., Harrison, Thomas S., Kuijper, Ed, Rhodes, Johanna, Sheppard, Donald C., Warris, Adilia, White, P. Lewis, Xu, Jianping, Zwaan, Bas, Verweij, Paul E.

“…Invasive fungal infections pose an important threat to public health and are an under-recognized component of antimicrobial resistance, an emerging crisis…”
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Pharmacokinetics and Pharmacodynamics of Posaconazole by Chen, Lu, Krekels, Elke H. J., Verweij, Paul. E., Buil, Jochem B., Knibbe, Catherijne A. J., Brüggemann, Roger J. M.

“…Posaconazole is typically used for preventing invasive yeast and mold infections such as invasive aspergillosis in high-risk immunocompromised patients. The…”
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Clinical implications of globally emerging azole resistance in Aspergillus fumigatus by Meis, Jacques F., Chowdhary, Anuradha, Rhodes, Johanna L., Fisher, Matthew C., Verweij, Paul E.

“…Aspergillus fungi are the cause of an array of diseases affecting humans, animals and plants. The triazole antifungal agents itraconazole, voriconazole,…”
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Defining and managing COVID-19-associated pulmonary aspergillosis: the 2020 ECMM/ISHAM consensus criteria for research and clinical guidance by Koehler, Philipp, Bassetti, Matteo, Chakrabarti, Arunaloke, Chen, Sharon C A, Colombo, Arnaldo Lopes, Hoenigl, Martin, Klimko, Nikolay, Lass-Flörl, Cornelia, Oladele, Rita O, Vinh, Donald C, Zhu, Li-Ping, Böll, Boris, Brüggemann, Roger, Gangneux, Jean-Pierre, Perfect, John R, Patterson, Thomas F, Persigehl, Thorsten, Meis, Jacques F, Ostrosky-Zeichner, Luis, White, P Lewis, Verweij, Paul E, Cornely, Oliver A

“…Severe acute respiratory syndrome coronavirus 2 causes direct damage to the airway epithelium, enabling aspergillus invasion. Reports of COVID-19-associated…”
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Aspergillus fumigatus and pan-azole resistance: who should be concerned? by Wiederhold, Nathan P., Verweij, Paul E.

“…Although clinical outcomes in the treatment of aspergillosis have markedly improved with the availability of newer triazoles, the development of resistance to…”
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Fungal infections should be part of the core outcome set for COVID-19 by Verweij, Paul E, Alanio, Alexandre

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COVID-19-associated Pulmonary Aspergillosis by van Arkel, Andreas L E, Rijpstra, Tom A, Belderbos, Huub N A, van Wijngaarden, Peter, Verweij, Paul E, Bentvelsen, Robbert G

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Invasive pulmonary aspergillosis complicating severe influenza: epidemiology, diagnosis and treatment by Vanderbeke, Lore, Spriet, Isabel, Breynaert, Christine, Rijnders, Bart J.A, Verweij, Paul E, Wauters, Joost

“…PURPOSE OF REVIEWBacterial super-infection of critically ill influenza patients is well known, but in recent years, more and more reports describe invasive…”
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Discovery and characterization of novel Aspergillus fumigatus mycoviruses by Zoll, Jan, Verweij, Paul E, Melchers, Willem J G

“…In the last few years, increasing numbers of viruses infecting fungi have been identified. In this study, we used an in silico approach for the analysis of…”
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Molecular Diagnosis of Invasive Aspergillosis and Detection of Azole Resistance by a Newly Commercialized PCR Kit by Dannaoui, Eric, Gabriel, Frédéric, Gaboyard, Manuel, Lagardere, Gaëlle, Audebert, Lucile, Quesne, Gilles, Godichaud, Sandrine, Verweij, Paul E, Accoceberry, Isabelle, Bougnoux, Marie-Elisabeth

“…is the main species responsible for aspergillosis in humans. The diagnosis of aspergillosis remains difficult, and the rapid emergence of azole resistance in…”
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Triazole fungicides can induce cross-resistance to medical triazoles in Aspergillus fumigatus by Snelders, Eveline, Camps, Simone M T, Karawajczyk, Anna, Schaftenaar, Gijs, Kema, Gert H J, van der Lee, Henrich A, Klaassen, Corné H, Melchers, Willem J G, Verweij, Paul E

“…Azoles play an important role in the management of Aspergillus diseases. Azole resistance is an emerging global problem in Aspergillus fumigatus, and may…”
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Molecular mechanisms of acquired antifungal drug resistance in principal fungal pathogens and EUCAST guidance for their laboratory detection and clinical implications by Rogers, Thomas R, Verweij, Paul E, Castanheira, Mariana, Dannaoui, Eric, White, P Lewis, Arendrup, Maiken Cavling

“…Abstract The increasing incidence and changing epidemiology of invasive fungal infections continue to present many challenges to their effective management…”
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ESCMID COVID-19 living guidelines: drug treatment and clinical management by Bartoletti, Michele, Azap, Ozlem, Barac, Aleksandra, Bussini, Linda, Ergonul, Onder, Krause, Robert, Paño-Pardo, José Ramón, Power, Nicholas R., Sibani, Marcella, Szabo, Balint Gergely, Tsiodras, Sotirios, Verweij, Paul E., Zollner-Schwetz, Ines, Rodríguez-Baño, Jesús

“…In January 2021, the ESCMID Executive Committee decided to launch a new initiative to develop ESCMID guidelines on several COVID-19-related issues, including…”
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The fading boundaries between patient and environmental routes of triazole resistance selection in Aspergillus fumigatus by Buil, Jochem B, Hare, Rasmus K, Zwaan, Bas J, Arendrup, Maiken C, Melchers, Willem J G, Verweij, Paul E

“…Alternatively, patients may inhale inherently triazole-resistant A. fumigatus spores, supported by the fact that in every case with a wild-type A. fumigatus…”
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Azole resistance in Aspergillus fumigatus : a side-effect of environmental fungicide use? by Verweij, Paul E, Dr, Snelders, Eveline, MSc, Kema, Gert HJ, PhD, Mellado, Emilia, PhD, Melchers, Willem JG, PhD

“…Summary Invasive aspergillosis due to multi-azole-resistant Aspergillus fumigatus has emerged in the Netherlands since 1999, with 6·0–12·8% of patients…”
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Triazole resistance surveillance in Aspergillus fumigatus by Resendiz Sharpe, Agustin, Lagrou, Katrien, Meis, Jacques F, Chowdhary, Anuradha, Lockhart, Shawn R, Verweij, Paul E

“…Abstract Triazole resistance is an increasing concern in the opportunistic mold Aspergillus fumigatus. Resistance can develop through exposure to azole…”
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Voriconazole Resistance and Mortality in Invasive Aspergillosis: A Multicenter Retrospective Cohort Study by Lestrade, Pieter P, Bentvelsen, Robbert G, Schauwvlieghe, Alexander F A D, Schalekamp, Steven, van der Velden, Walter J F M, Kuiper, Ed J, van Paassen, Judith, van der Hoven, Ben, van der Lee, Henrich A, Melchers, Willem J G, de Haan, Anton F, van der Hoeven, Hans L, Rijnders, Bart J A, van der Beek, Martha T, Verweij, Paul E

“…Abstract Background Triazole resistance is an increasing problem in invasive aspergillosis (IA). Small case series show mortality rates of 50%–100% in patients…”
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