Search Results - "Vervliet, T"

Bcl-2 proteins and calcium signaling: complexity beneath the surface by Vervliet, T, Parys, J B, Bultynck, G

“…Antiapoptotic Bcl-2-family members are well known for their ‘mitochondrial’ functions as critical neutralizers of proapoptotic Bcl-2-family members, including…”
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Selective regulation of IP3-receptor-mediated Ca2+ signaling and apoptosis by the BH4 domain of Bcl-2 versus Bcl-Xl by Monaco, G, Decrock, E, Akl, H, Ponsaerts, R, Vervliet, T, Luyten, T, De Maeyer, M, Missiaen, L, Distelhorst, C W, De Smedt, H, Parys, J B, Leybaert, L, Bultynck, G

“…Antiapoptotic B-cell lymphoma 2 (Bcl-2) targets the inositol 1,4,5-trisphosphate receptor (IP 3 R) via its BH4 domain, thereby suppressing IP 3 R Ca 2+ -flux…”
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IP3R2 levels dictate the apoptotic sensitivity of diffuse large B-cell lymphoma cells to an IP3R-derived peptide targeting the BH4 domain of Bcl-2 by Akl, H, Monaco, G, La Rovere, R, Welkenhuyzen, K, Kiviluoto, S, Vervliet, T, Molgó, J, Distelhorst, C W, Missiaen, L, Mikoshiba, K, Parys, J B, De Smedt, H, Bultynck, G

“…Disrupting inositol 1,4,5-trisphosphate (IP 3 ) receptor (IP 3 R)/B-cell lymphoma 2 (Bcl-2) complexes using a cell-permeable peptide (stabilized TAT-fused IP 3…”
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A deep phenotyping study in mouse and iPSC models to understand the role of oligodendroglia in optic neuropathy in Wolfram syndrome by Ahuja, K, Vandenabeele, M, Nami, F, Lefevere, E, Van Hoecke, J, Bergmans, S, Claes, M, Vervliet, T, Neyrinck, K, Burg, T, De Herdt, D, Bhaskar, P, Zhu, Y, Looser, Z J, Loncke, J, Gsell, W, Plaas, M, Agostinis, P, Swinnen, J V, Van Den Bosch, L, Bultynck, G, Saab, A S, Wolfs, E, Chai, Y C, Himmelreich, U, Verfaillie, C, Moons, L, De Groef, L

“…Wolfram syndrome (WS) is a rare childhood disease characterized by diabetes mellitus, diabetes insipidus, blindness, deafness, neurodegeneration and eventually…”
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Neuroprotective properties of anti-apoptotic BCL-2 proteins in 5xFAD mouse model of Alzheimer’s disease by Chernyuk, D., Callens, M., Polozova, M., Gordeev, A., Chigriai, M., Rakovskaya, A., Ilina, A., Pchitskaya, E., Van den Haute, C., Vervliet, T., Bultynck, G., Bezprozvanny, I.

“…Alzheimer's disease (AD) is the most common cause of dementia. An early feature of the AD pathology is the dysregulation of intracellular Ca2+ signaling in…”
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Bax Inhibitor-1 is a novel IP3 receptor-interacting and -sensitizing protein by Kiviluoto, S, Schneider, L, Luyten, T, Vervliet, T, Missiaen, L, De Smedt, H, Parys, J B, Methner, A, Bultynck, G

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Ryanodine Receptors in Autophagy: Implications for Neurodegenerative Diseases? by Vervliet, Tim

“…Intracellular Ca signaling is important in the regulation of several cellular processes including autophagy. The endoplasmic reticulum (ER) is the main and…”
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Bax Inhibitor-1 is a novel IP sub(3) receptor-interacting and -sensitizing protein by Kiviluoto, S, Schneider, L, Luyten, T, Vervliet, T, Missiaen, L, De Smedt, H, Parys, J B, Methner, A, Bultynck, G

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Selective regulation of IP sub(3)-receptor-mediated Ca super(2+) signaling and apoptosis by the BH4 domain of Bcl-2 versus Bcl-Xl by Monaco, G, Decrock, E, Akl, H, Ponsaerts, R, Vervliet, T, Luyten, T, De Maeyer, M, Missiaen, L, Distelhorst, C W, De Smedt, H, Parys, J B, Leybaert, L, Bultynck, G

“…Antiapoptotic B-cell lymphoma 2 (Bcl-2) targets the inositol 1,4,5-trisphosphate receptor (IP sub(3)R) via its BH4 domain, thereby suppressing IP sub(3)R Ca…”
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IP sub(3)R2 levels dictate the apoptotic sensitivity of diffuse large B-cell lymphoma cells to an IP sub(3)R-derived peptide targeting the BH4 domain of Bcl-2 by Akl, H, Monaco, G, La Rovere, R, Welkenhuyzen, K, Kiviluoto, S, Vervliet, T, Molgo, J, Distelhorst, C W, Missiaen, L, Mikoshiba, K, Parys, J B, De Smedt, H, Bultynck, G

“…Disrupting inositol 1,4,5-trisphosphate (IP sub(3)) receptor (IP sub(3)R)/B-cell lymphoma 2 (Bcl-2) complexes using a cell-permeable peptide (stabilized…”
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