Search Results - "Vertongen, Pascale"

Role of Scaffolds, Subchondral, Intra-Articular Injections of Fresh Autologous Bone Marrow Concentrate Regenerative Cells in Treating Human Knee Cartilage Lesions: Different Approaches and Different Results by Hernigou, Jacques, Vertongen, Pascale, Rasschaert, Joanne, Hernigou, Philippe

“…The value of bone marrow aspirate concentrates for treatment of human knee cartilage lesions is unclear. Most of the studies were performed with…”
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Induction of Stearoyl-CoA 9-Desaturase 1 Protects Human Mesenchymal Stromal Cells Against Palmitic Acid-Induced Lipotoxicity and Inflammation by Dalla Valle, Antoine, Vertongen, Pascale, Spruyt, Delphine, Lechanteur, Jessica, Suain, Valérie, Gaspard, Nathalie, Brion, Jean-Pierre, Gangji, Valérie, Rasschaert, Joanne

“…In bone diseases such as osteonecrosis and osteoporosis, a shift toward a preferential differentiation of mesenchymal stromal cells (MSC) into adipocytes at…”
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Binding characteristics of [ 3H]ucb 30889 to levetiracetam binding sites in rat brain by Gillard, Michel, Fuks, Bruno, Michel, Philippe, Vertongen, Pascale, Massingham, Roy, Chatelain, Pierre

“…Levetiracetam (2 S-(2-oxo-1-pyrrolidinyl)butanamide, KEPPRA®), a novel antiepileptic drug, has been shown to bind to a specific binding site located in brain…”
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Contribution of the Carboxyl Terminus of the VPAC1 Receptor to Agonist-induced Receptor Phosphorylation, Internalization, and Recycling by Langlet, Christelle, Langer, Ingrid, Vertongen, Pascale, Gaspard, Nathalie, Vanderwinden, Jean-Marie, Robberecht, Patrick

“…When exposed to vasoactive intestinal peptide (VIP), the human wild type VPAC1 receptor expressed in Chinese hamster ovary (CHO) cells is rapidly…”
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Two Basic Residues of the h-VPAC1 Receptor Second Transmembrane Helix Are Essential for Ligand Binding and Signal Transduction by Solano, Rosa Maria, Langer, Ingrid, Perret, Jason, Vertongen, Pascale, Juarranz, Maria Guillerma, Robberecht, Patrick, Waelbroeck, Magali

“…We mutated the vasoactive intestinal peptide (VIP) Asp3 residue and two VPAC1receptor second transmembrane helix basic residues (Arg188and Lys195). VIP had a…”
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Development of high affinity selective VIP1 receptor agonists by Gourlet, P, Vandermeers, A, Vertongen, P, Rathe, J, De Neef, P, Cnudde, J, Waelbroeck, M, Robberecht, P

“…The biological effects of VIP are mediated by at least two VIP receptors: the VIP1 and the VIP2 receptors that were cloned in rat, human and mice. As the mRNA…”
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Autoradiographic Visualization of the Receptor Subclasses for Vasoactive Intestinal Polypeptide (VIP) in Rat Brain by Vertongen, Pascale, Schiffmann, Serge N, Gourlet, Philippe, Robberecht, Patrick

“…Vertongen, P., S. N. Schiffmann, P. Gourlet and P. Robberecht. Autoradiographic visualization of the receptor subclasses for Vasoactive Intestinal Polypeptide…”
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Autoradiographic Visualization of the Receptor Subclasses for Vasoactive Intestinal Polypeptide (VIP) in Rat Brain by VERTONGEN, PASCALE, SCHIFFMANN, SERGE N., GOURLET, PHILIPPE, ROBBERECHT, PATRICK

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Osteonecrosis of the Femoral Head: Lipotoxicity Exacerbation in MSC and Modifications of the Bone Marrow Fluid by Gillet, Celine, Dalla Valle, Antoine, Gaspard, Nathalie, Spruyt, Delphine, Vertongen, Pascale, Lechanteur, Jessica, Rigutto, Sabrina, Dragan, Elena-Raluca, Heuschling, Audrey, Gangji, Valerie, Rasschaert, Joanne

“…Osteonecrosis of the femoral head (ON) is a multifactorial bone disease that can evolve to a progressive destruction of the hip joint. Different pathogenic…”
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Analysis of the glucagon receptor first extracellular loop by the substituted cysteine accessibility method by Roberts, David J., Vertongen, Pascale, Waelbroeck, Magali

“…[Display omitted] ► SCAM of the first glucagon receptor extracellular loop (197–224). ► TM2 continues to position 202, TM3 from 215 ► Most side chains…”
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Effects of press-fit biphasic (collagen and HA/βTCP) scaffold with cell-based therapy on cartilage and subchondral bone repair knee defect in rabbits by Hernigou, Jacques, Vertongen, Pascale, Chahidi, Esfandiar, Kyriakidis, Theofylaktos, Dehoux, Jean-Paul, Crutzen, Magalie, Boutry, Sébastien, Larbanoix, Lionel, Houben, Sarah, Gaspard, Nathalie, Koulalis, Dimitrios, Rasschaert, Joanne

“…Introduction Human spontaneous osteonecrosis of the knee (SPONK) is still challenging as the current treatments do not allow the production of hyaline…”
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Differential alternative splicing of PACAP receptor in pituitary cell subpopulations by Vertongen, Pascale, Velkeniers, Brigitte, Hooghe-Peters, Elisabeth, Robberecht, Patrick

“…The capability of rat pituitary cells to express receptors for pituitary adenylate cyclase activating polypeptide (PACAP) and VIP was evaluated by binding…”
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Mutational and Cysteine Scanning Analysis of the Glucagon Receptor N-terminal Domain by Prévost, Martine, Vertongen, Pascale, Raussens, Vincent, Roberts, David Jonathan, Cnudde, Johnny, Perret, Jason, Waelbroeck, Magali

“…The glucagon receptor belongs to the B family of G-protein coupled receptors. Little structural information is available about this receptor and its…”
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The Long-Acting Vasoactive Intestinal Polypeptide Agonist RO 25-1553 Is Highly Selective of the VIP 2 Receptor Subclass by Gourlet, Philippe, Vertongen, Pascale, Vandermeers, Andre, Vandermeers-piret, Marie-Claire, Rathe, Jean, De Neef, Philippe, Waelbroeck, Magali, Robberecht, Patrick

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Characterization of [3H]ucb 30889 binding to synaptic vesicle protein 2A in the rat spinal cord by Lambeng, Nathalie, Gillard, Michel, Vertongen, Pascale, Fuks, Bruno, Chatelain, Pierre

“…The novel antiepileptic drug levetiracetam ((2S-(2-oxo-1-pyrrolidinyl)butanamide, KEPPRA®) possesses a specific binding site in brain, which has very recently…”
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Expression of vascular endothelial growth factor (VEGF) and VEGF receptors in human neuroblastomas by Langer, Ingrid, Vertongen, Pascale, Perret, Jason, Fontaine, Jeanine, Atassi, Ghanem, Robberecht, Patrick

“…Background Vascular endothelial growth factor (VEGF) is a specific endothelial cell mitogen that stimulates angiogenesis and plays a crucial role in tumor…”
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Localization and photoaffinity labelling of the levetiracetam binding site in rat brain and certain cell lines by Fuks, Bruno, Gillard, Michel, Michel, Philippe, Lynch, Berkley, Vertongen, Pascale, Leprince, Pierre, Klitgaard, Henrik, Chatelain, Pierre

“…Levetiracetam (2 S-(2-oxo-1-pyrrolidinyl)butanamide, KEPPRA®), a novel antiepileptic drug, has been shown to bind to a specific binding site located in the…”
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Motilin and erythromycin-A share a common binding site in the third transmembrane segment of the motilin receptor by Xu, Luo, Depoortere, Inge, Vertongen, Pascale, Waelbroeck, Magali, Robberecht, Patrick, Peeters, Theo L.

“…The motilin receptor (MTLR) represents a clinically useful pharmacological target, as agonists binding to the MTLR have gastroprokinetic properties. In order…”
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A Small Sequence in the Third Intracellular Loop of the VPAC1 Receptor Is Responsible for Its Efficient Coupling to the Calcium Effector by Langer, Ingrid, Vertongen, Pascale, Perret, Jason, Waelbroeck, Magali, Robberecht, Patrick

“…The stimulatory effect of VIP on intracellular calcium concentration ([Ca2+]i) has been investigated in Chinese hamster ovary cells stably transfected with the…”
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Ac His1 [D-Phe2, K15, R16, L27] VIP (3-7)/GRF (8-27) - a VPAC1 receptor antagonist: is an inverse agonist on two constitutively active truncated VPAC1 receptors by VERTONGEN, Pascale, LANGLET, Christelle, LANGER, Ingrid, GASPARD, Nathalie, ROBBERECHT, Patrick

“…C-terminally truncated human VPAC(1) receptors were constructed and stably transfected in Chinese hamster ovary (CHO) cells. Selected clones expressing…”
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