Search Results - "Vertommen, Jan"

Toward the establishment of standardized in vitro tests for lipid-based formulations, part 1: method parameterization and comparison of in vitro digestion profiles across a range of representative formulations by Williams, Hywel D, Sassene, Philip, Kleberg, Karen, Bakala-N'Goma, Jean-Claude, Calderone, Marilyn, Jannin, Vincent, Igonin, Annabel, Partheil, Anette, Marchaud, Delphine, Jule, Eduardo, Vertommen, Jan, Maio, Mario, Blundell, Ross, Benameur, Hassan, Carrière, Frédéric, Müllertz, Anette, Porter, Christopher J H, Pouton, Colin W

“…The Lipid Formulation Classification System Consortium is an industry-academia collaboration, established to develop standardized in vitro methods for the…”
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Toward the Establishment of Standardized In Vitro Tests for Lipid-Based Formulations, Part 3: Understanding Supersaturation Versus Precipitation Potential During the In Vitro Digestion of Type I, II, IIIA, IIIB and IV Lipid-Based Formulations by Williams, Hywel D., Sassene, Philip, Kleberg, Karen, Calderone, Marilyn, Igonin, Annabel, Jule, Eduardo, Vertommen, Jan, Blundell, Ross, Benameur, Hassan, Müllertz, Anette, Pouton, Colin W., Porter, Christopher J. H.

“…Purpose Recent studies have shown that digestion of lipid-based formulations (LBFs) can stimulate both supersaturation and precipitation. The current study has…”
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Antioxidant status and lipoprotein peroxidation in chronic fatigue syndrome by y Keenoy, Begoña Manuel, Moorkens, Greta, Vertommen, Jan, De Leeuw, Ivo

“…The aetiology and pathogenesis of the Chronic Fatigue Syndrome (CFS) are still largely unresolved. Accompanying metabolic disorders such as selective n-6 fatty…”
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Minimally-invasive and non-invasive continuous glucose monitoring systems: indications, advantages, limitations and clinical aspects by De Block, Christophe, Vertommen, Jan, Manuel-y-Keenoy, Begoña, Van Gaal, Luc

“…Accurate and reliable devices sensing glucose on a (near)-continuous basis may facilitate specific therapeutic adjustments that need to be made to avoid hypo-…”
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Postprandial glucose monitoring in type 1 diabetes mellitus: use of a continuous subcutaneous monitoring device by Manuel-y-Keenoy, Begoña, Vertommen, Jan, Abrams, Pascale, Van Gaal, Luc, De Leeuw, Ivo, Messeri, Dimitri, Poscia, Alessandro

“…Background Pre‐prandial glucose gives insufficient information on glycemic excursions throughout the day. We aimed to test a continuous subcutaneous…”
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Toward the Establishment of Standardized in Vitro Tests for Lipid-Based Formulations. 2. The Effect of Bile Salt Concentration and Drug Loading on the Performance of Type I, II, IIIA, IIIB, and IV Formulations during in Vitro Digestion by Williams, Hywel D, Anby, Mette U, Sassene, Philip, Kleberg, Karen, Bakala-N’Goma, Jean-Claude, Calderone, Marilyn, Jannin, Vincent, Igonin, Annabel, Partheil, Anette, Marchaud, Delphine, Jule, Eduardo, Vertommen, Jan, Maio, Mario, Blundell, Ross, Benameur, Hassan, Carrière, Frédéric, Müllertz, Anette, Pouton, Colin W, Porter, Christopher J. H

“…The LFCS Consortium was established to develop standardized in vitro tests for lipid-based formulations (LBFs) and to examine the utility of these tests to…”
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Toward the Establishment of Standardized In Vitro Tests for Lipid-Based Formulations. 5. Lipolysis of Representative Formulations by Gastric Lipase by Bakala-N’Goma, Jean-Claude, Williams, Hywel D., Sassene, Philip J., Kleberg, Karen, Calderone, Marilyn, Jannin, Vincent, Igonin, Annabel, Partheil, Anette, Marchaud, Delphine, Jule, Eduardo, Vertommen, Jan, Maio, Mario, Blundell, Ross, Benameur, Hassan, Müllertz, Anette, Pouton, Colin W., Porter, Christopher J. H., Carrière, Frédéric

“…Purpose Lipid-based formulations (LBF) are substrates for digestive lipases and digestion can significantly alter their properties and potential to support…”
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Toward the Establishment of Standardized In Vitro Tests for Lipid-Based Formulations, Part 6: Effects of Varying Pancreatin and Calcium Levels by Sassene, Philip, Kleberg, Karen, Williams, Hywel D., Bakala-N’Goma, Jean-Claude, Carrière, Frédéric, Calderone, Marilyn, Jannin, Vincent, Igonin, Annabel, Partheil, Anette, Marchaud, Delphine, Jule, Eduardo, Vertommen, Jan, Maio, Mario, Blundell, Ross, Benameur, Hassan, Porter, Christopher J. H., Pouton, Colin W., Müllertz, Anette

“…The impact of pancreatin and calcium addition on a wide array of lipid-based formulations (LBFs) during in vitro lipolysis, with regard to digestion rates and…”
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Toward the establishment of standardized in vitro tests for lipid-based formulations, part 4: proposing a new lipid formulation performance classification system by Williams, Hywel D, Sassene, Philip, Kleberg, Karen, Calderone, Marilyn, Igonin, Annabel, Jule, Eduardo, Vertommen, Jan, Blundell, Ross, Benameur, Hassan, Müllertz, Anette, Porter, Christopher J H, Pouton, Colin W

“…The Lipid Formulation Classification System Consortium looks to develop standardized in vitro tests and to generate much-needed performance criteria for…”
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Epidural neostigmine and clonidine improves the quality of combined spinal epidural analgesia in labour: A randomised, double-blind controlled trial by Boogmans, Thomas, Vertommen, Jan, Valkenborgh, Tom, Devroe, Sarah, Roofthooft, Eva, Van de Velde, Marc

“…BACKGROUNDIn labour analgesia, the combination of epidural clonidine and neostigmine as adjuvants to local anaesthetics and opioids is under investigation to…”
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The effects of the addition of sufentanil to 0.125% bupivacaine on the quality of analgesia during labor and on the incidence of instrumental deliveries by VERTOMMEN, J. D, VENDERMEULEN, E, VAN ASSCHE, A. F, VAN AKEN, H, VAES, L, SOETENS, M, VAN STEENBERGE, A, MOURISSE, P, WILLAERT, J, NOORDUIN, H, DEVLIEGER, H

“…In a double-blinded, randomized, prospective multi-center study of 695 women, we investigated whether epidural injection of sufentanil added to 0.125%…”
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Hemodynamic Effects of Intravenous Isoproterenol Versus Saline in the Parturient by Marcus, Marco A. E, Vertommen, Jan D, Van Aken, Hugo, Wouters, Patrick F, Van Assche, Andre, Spitz, Bernard

“…The use of epinephrine as a test dose for epidural analgesia in obstetrics remains controversial.Isoproterenol as a test dose may be efficacious in the…”
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Toward the Establishment of Standardized In Vitro Tests for Lipid-Based Formulations, Part 3: Understanding Supersaturation Versus Precipitation Potential During the In Vitro Digestion of Type I, II, IIIA, IIIB and IV Lipid-Based Formulations: Recent Advances in Lipid-Based Formulation Technology by WILLIAMS, Hywel D, SASSENE, Philip, POUTON, Colin W, PORTER, Christopher J. H, KLEBERG, Karen, CALDERONE, Marilyn, IGONIN, Annabel, JULE, Eduardo, VERTOMMEN, Jan, BLUNDELL, Ross, BENAMEUR, Hassan, MÜLLERTZ, Anette

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Impact of Vitamin E supplementation on lipoprotein peroxidation and composition in Type 1 diabetic patients treated with Atorvastatin by Manuel-y-Keenoy, Begoña, Vinckx, Marleen, Vertommen, Jan, van Gaal, Luc, de Leeuw, Ivo

“…Objective: To investigate the impact of Vitamin E on lipids and peroxidation during statin treatment. Research Design and Methods: T1DM patients with high…”
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Evolution of Serum α-Tocopherol in the Postprandial and Postabsorptive Phases in Type 1 Diabetes Mellitus by MANUEL-Y-KEENOY, BEGOÑA, VAN CAMPENHOUT, ANN, VERTOMMEN, JAN, VAN GAAL, LUC, DE LEEUW, IVO

“…: Blood glucose, lipids, α‐tocopherol, and malondialdehyde were monitored in type 1 diabetes mellitus patients for 8 hours after a standard fat‐rich breakfast…”
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Effects of long-term supplementation with moderate pharmacologic doses of vitamin E are saturable and reversible in patients with type 1 diabetes by ENGELEN, Wendy, KEENOY, Begona Manuel Y, VERTOMMEN, Jan, DE LEEUW, Ivo

“…Vitamin E supplementation has been proposed as adjunctive therapy to counteract the increased LDL oxidation in diabetes and thus prevent or delay…”
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Effects of Atorvastatin on LDL sub-fractions and peroxidation in type 1 diabetic patients: a randomised double-blind placebo-controlled study by Manuel-y-Keenoy, Begoña, Van Campenhout, Christel, Vertommen, Jan, De Leeuw, Ivo

“…Background Patients with diabetes have an increased risk of both developing and dying from cardiovascular disease, and, currently, more aggressive…”
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Postprandial glucose monitoring in type 1 diabetes mellitus: use of a continuous subcutaneous monitoring device: Current applications of continuous glucose monitoring by MANUEL-Y-KEENOY, Begona, VERTOMMEN, Jan, ABRAMS, Pascale, VAN GAAL, Luc, DE LEEUW, Ivo, MESSERI, Dimitri, POSCIA, Alessandro

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Effects of long-term supplementation with moderate pharmacologic doses of vitamin E are saturable and reversible in patients with type 1 diabetes123 by Engelen, Wendy, Keenoy, Begoña Manuel y, Vertommen, Jan, De Leeuw, Ivo

“…Vitamin E supplementation has been proposed as adjunctive therapy to counteract the increased LDL oxidation in diabetes and thus prevent or delay…”
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The in vitro oxidizability of lipoprotein particles in obese and non-obese subjects by Van Gaal, Luc F, Vertommen, Jan, De Leeuw, Ivo H

“…There exists much evidence suggesting a major role for the oxidized low density lipoprotein (LDL) and VLDL particles in the pathogenesis of atherosclerosis…”
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