Search Results - "Vertel, B M"
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cDNA cloning of chick cartilage chondroitin sulfate (aggrecan) core protein and identification of a stop codon in the aggrecan gene associated with the chondrodystrophy, nanomelia
Published in The Journal of biological chemistry (05-11-1993)“…We previously reported the cloning and sequencing of a 1.5-kilobase cDNA which encoded a portion of the chondroitin sulfate domain from the chick cartilage…”
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Topography of glycosylation and UDP-xylose production
Published in The Journal of biological chemistry (25-05-1993)“…In order to define the location and organization of the numerous reactions involved in polysaccharide assembly during synthesis of proteoglycans and…”
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The chondrodystrophy, nanomelia : biosynthesis and processing of the defective aggrecan precursor
Published in Biochemical journal (01-07-1994)“…The lethal chicken mutation nanomelia leads to severe skeletal defects because of a deficiency of aggrecan, which is the largest aggregating chondroitin…”
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4
Xylosylation is an endoplasmic reticulum to Golgi event
Published in The Journal of biological chemistry (25-05-1993)“…The subcellular site of xylosylation, the first carbohydrate modification of the core protein that initiates glycosaminoglycan chain synthesis, was…”
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Aggrecan from start to finish
Published in Journal of bone and mineral metabolism (01-01-2000)Get full text
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Precursors of Chondroitin Sulfate Proteoglycan Are Segregated within a Subcompartment of the Chondrocyte Endoplasmic Reticulum
Published in The Journal of cell biology (01-10-1989)“…Immunocytochemical methods were used at the levels of light and electron microscopy to examine the intracellular compartments of chondrocytes involved in…”
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Nanomelic chondrocytes synthesize, but fail to translocate, a truncated aggrecan precursor
Published in Journal of cell science (01-03-1993)“…Cartilage extracellular matrix (ECM) is composed primarily of type II collagen and large, link stabilized aggregates of hyaluronic acid and chondroitin sulfate…”
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Nanomelic chondrocytes synthesize a glycoprotein related to chondroitin sulfate proteoglycan core protein
Published in The Journal of biological chemistry (25-11-1988)“…Chicken embryos homozygous for the autosomal recessive gene nanomelia exhibit cartilage defects, synthesize low levels of cartilage chondroitin sulfate…”
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Translation and Characterization of Messenger RNAs in Differentiating Chicken Cartilage
Published in Proceedings of the National Academy of Sciences - PNAS (01-10-1979)“…Total RNA, prepared from chicken limb bud cultures undergoing differentiation to cartilage, has been translated in a wheat germ cell-free protein-synthesizing…”
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The ins and outs of aggrecan
Published in Trends in Cell Biology (01-12-1995)“…Aggrecan is a large and highly complex macromolecule, uniquely structured to fill space in the extracellular matrix (ECM) of cartilage. Lethal…”
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Book Review Journal Article -
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Simultaneous localization of type II collagen and core protein of chondroitin sulfate proteoglycan in individual chondrocytes [Chickens, antigens, antibodies]
Published in Proceedings of the National Academy of Sciences - PNAS (01-03-1979)“…In order to investigate the coordinated synthesis of matrix components by individual chondrocytes, specific antibodies to type I collagen, type II collagen,…”
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Extracellular Matrix Formation by Chondrocytes in Monolayer Culture
Published in The Journal of cell biology (01-07-1981)“…In previous studies were have reported on the secretion and extracellular deposition of type II collagen and fibronectin and chondroitin sulfate proteoglycan…”
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Intracellular localization of engineered proteoglycans
Published in Methods in molecular biology (Clifton, N.J.) (2001)Get more information
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Stimulation and Inhibition of Myoblast Differentiation by Hormones
Published in In Vitro (01-12-1984)“…The growth and differentiation of L6 myoblasts are subject to control by two proteins secreted by cells of the Buffalo rat liver line. The first of these, rat…”
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The Biochemically and Immunologically Distinct CSPG of Notochord Is a Product of the Aggrecan Gene
Published in Developmental biology (01-10-1995)“…Using the monoclonal antibody S103L, which reacts specifically with an epitope in the chondroitin sulfate-rich domain of the chick cartilage chondroitin…”
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Intracellular features of type II procollagen and chondroitin sulfate proteoglycan synthesis in chondrocytes
Published in Journal of cellular biochemistry (1985)“…The intracellular compartments of chondrocytes involved in the synthesis and processing of type II procollagen and chondroitin sulfate proteoglycan (CSPG)…”
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Cell-free translation of messenger RNA for chondroitin sulphate proteoglycan core protein in rat cartilage
Published in Biochemical journal (01-01-1984)“…Total RNA was extracted from the cartilage tissues rat Swarm chondrosarcoma, neonatal-rat breastplate and embryonic-chicken sterna and translated in wheat-germ…”
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Immunofluorescence studies on cartilage matrix synthesis. The synthesis of link protein, chondroitin sulfate proteoglycan monomer and type II collagen
Published in Experimental cell research (01-01-1985)“…A comparison of the synthesis and deposition of fibrous type II collagen and the constituents of chondroitin sulfate proteoglycan (CSPG) aggregates, CSPG…”
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Aggrecan Domains Expected to Traffic through the Exocytic Pathway Are Misdirected to the Nucleus
Published in Experimental cell research (15-02-2001)“…In this article, we report the misdirected targeting of expressed aggrecan domains. Aggrecan, the chondroitin sulfate (CS) proteoglycan of cartilage, normally…”
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